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Featured 5 Star Serra Mesa Hotels

Fully refundableReserve now, pay when you stay
The price is $338 per night from Mar 23 to Mar 24
$338
includes taxes & fees
Mar 23 - Mar 24
Stay at this 5-star luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...

Fully refundableReserve now, pay when you stay
The price is $315 per night from Mar 23 to Mar 24
$315
includes taxes & fees
Mar 23 - Mar 24
Stay at this 5-star luxury hotel in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful ...

Fully refundableReserve now, pay when you stay
The price is $771 per night from Apr 5 to Apr 6
$771
includes taxes & fees
Apr 5 - Apr 6
Stay at this 5-star luxury hotel in San Diego. Enjoy free WiFi, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
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Fully refundableReserve now, pay when you stay
The price is $564 per night from Apr 8 to Apr 9
$564
includes taxes & fees
Apr 8 - Apr 9
Stay at this 5-star luxury hotel in La Jolla. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...

Fully refundableReserve now, pay when you stay
The price is $547 per night from Mar 11 to Mar 12
$547
includes taxes & fees
Mar 11 - Mar 12
Stay at this 5-star luxury hotel in Del Mar. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...

Fully refundableReserve now, pay when you stay
The price is $486 per night from Mar 18 to Mar 19
$486
includes taxes & fees
Mar 18 - Mar 19
Stay at this 5-star luxury hotel in Rancho Santa Fe. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our ...

The price is $1,067 per night from Mar 12 to Mar 13
$1,067
includes taxes & fees
Mar 12 - Mar 13
Stay at this 5-star luxury resort in Coronado. Enjoy free WiFi, 3 outdoor pools, and 7 restaurants. Popular attractions Petco Park and USS Midway Museum are ...

Fully refundableReserve now, pay when you stay
The price is $1,033 per night from Mar 11 to Mar 12
$1,033
includes taxes & fees
Mar 11 - Mar 12
Book a stay at this spa resort in Rancho Santa Fe. Enjoy 2 outdoor pools, a full-service spa, and 2 restaurants. Popular attractions Del Mar Racetrack and Del ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Serra Mesa Hotels
- The Dana on Mission Bay
- San Diego Marriott La Jolla
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
- San Diego Mission Bay Resort
- Comfort Inn Sea World Area
- Wyndham San Diego Bayside
- Inn By The Sea La Jolla
- Omni San Diego Hotel
- The Little Italy Hotel Downtown San Diego
- Humphreys Half Moon Inn
- Sheraton San Diego Resort
- Hard Rock Hotel San Diego
Top Attractions in Serra Mesa
- Hotels near Stadium Golf Center & Batting Cages (1.51 mi)
- Hotels near San Diego Zoo (4.68 mi)
- Hotels near Mission Bay (5.38 mi)
- Hotels near San Ysidro Border Crossing (18.98 mi)
- Hotels near San Diego Convention Center (6.8 mi)
- Hotels near Balboa Park (4.91 mi)
- Hotels near Mission Beach (7 mi)
- Hotels near San Diego State University (4.48 mi)
- Hotels near Marine Corps Recruit Depot (5.5 mi)
- Hotels near Port of San Diego (6.24 mi)
- Hotels near Petco Park (6.69 mi)
- Hotels near Hotel del Coronado (8.73 mi)
- Hotels near Hotel Circle (3.63 mi)
- Hotels near B Street Cruise Ship Terminal (6.25 mi)
- Hotels near Mission Beach Boardwalk (7.16 mi)
- Hotels near Naval Base San Diego (8.71 mi)
- Hotels near Naval Base Coronado (8.09 mi)
- Hotels near La Jolla Cove (8.42 mi)
- Hotels near USS Midway Museum (6.51 mi)
- Hotels near Coronado Beach (8.69 mi)
Nearby Cities
- San Diego Hotels (6.16 mi)
- Carlsbad Hotels (27.42 mi)
- La Jolla Hotels (7.98 mi)
- Coronado Hotels (8.48 mi)
- Del Mar Hotels (12.93 mi)
- Encinitas Hotels (18.44 mi)
- Chula Vista Hotels (11.68 mi)
- Escondido Hotels (22.05 mi)
- Cardiff-by-the-Sea Hotels (17.11 mi)
- Coronado Island Hotels (8.08 mi)
- El Cajon Hotels (10.25 mi)
- Solana Beach Hotels (15.09 mi)
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Car Rentals Near Serra Mesa
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