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Featured 4 Star Serra Mesa Hotels
Fully refundableReserve now, pay when you stay
The price is $257 per night from Mar 23 to Mar 24
$257
includes taxes & fees
Mar 23 - Mar 24
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Fully refundableReserve now, pay when you stay
The price is $277 per night from Apr 3 to Apr 4
$277
includes taxes & fees
Apr 3 - Apr 4
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Fully refundableReserve now, pay when you stay
The price is $281 per night from Mar 16 to Mar 17
$281
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...
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Fully refundableReserve now, pay when you stay
The price is $171 per night from Mar 16 to Mar 17
$171
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Fully refundableReserve now, pay when you stay
The price is $222 per night from Mar 23 to Mar 24
$222
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
Fully refundableReserve now, pay when you stay
The price is $322 per night from Apr 2 to Apr 3
$322
includes taxes & fees
Apr 2 - Apr 3
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
Fully refundableReserve now, pay when you stay
The price is $171 per night from Mar 14 to Mar 15
$171
includes taxes & fees
Mar 14 - Mar 15
Stay at this 4-star business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Fully refundableReserve now, pay when you stay
The price is $278 per night from Mar 15 to Mar 16
$278
includes taxes & fees
Mar 15 - Mar 16
Stay at this 4-star beach hotel in Coronado. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Fully refundableReserve now, pay when you stay
The price is $306 per night from Mar 27 to Mar 28
$306
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Fully refundableReserve now, pay when you stay
The price is $232 per night from Mar 13 to Mar 14
$232
includes taxes & fees
Mar 13 - Mar 14
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Fully refundableReserve now, pay when you stay
The price is $181 per night from Mar 14 to Mar 15
$181
includes taxes & fees
Mar 14 - Mar 15
Book a stay at this business-friendly hotel in San Diego. Enjoy 2 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Fully refundableReserve now, pay when you stay
The price is $202 per night from Mar 16 to Mar 17
$202
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Serra Mesa Hotels
- The Dana on Mission Bay
- San Diego Marriott La Jolla
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
- San Diego Mission Bay Resort
- Comfort Inn Sea World Area
- Wyndham San Diego Bayside
- Inn By The Sea La Jolla
- Omni San Diego Hotel
- The Little Italy Hotel Downtown San Diego
- Humphreys Half Moon Inn
- Sheraton San Diego Resort
- Hard Rock Hotel San Diego
Top Attractions in Serra Mesa
- Hotels near Stadium Golf Center & Batting Cages (1.51 mi)
- Hotels near San Diego Zoo (4.68 mi)
- Hotels near Mission Bay (5.38 mi)
- Hotels near San Ysidro Border Crossing (18.98 mi)
- Hotels near San Diego Convention Center (6.8 mi)
- Hotels near Balboa Park (4.91 mi)
- Hotels near Mission Beach (7 mi)
- Hotels near San Diego State University (4.48 mi)
- Hotels near Marine Corps Recruit Depot (5.5 mi)
- Hotels near Port of San Diego (6.24 mi)
- Hotels near Petco Park (6.69 mi)
- Hotels near Hotel del Coronado (8.73 mi)
- Hotels near Hotel Circle (3.63 mi)
- Hotels near B Street Cruise Ship Terminal (6.25 mi)
- Hotels near Mission Beach Boardwalk (7.16 mi)
- Hotels near Naval Base San Diego (8.71 mi)
- Hotels near Naval Base Coronado (8.09 mi)
- Hotels near La Jolla Cove (8.42 mi)
- Hotels near USS Midway Museum (6.51 mi)
- Hotels near Coronado Beach (8.69 mi)
Nearby Cities
- San Diego Hotels (6.16 mi)
- Carlsbad Hotels (27.42 mi)
- La Jolla Hotels (7.98 mi)
- Coronado Hotels (8.48 mi)
- Del Mar Hotels (12.93 mi)
- Encinitas Hotels (18.44 mi)
- Chula Vista Hotels (11.68 mi)
- Escondido Hotels (22.05 mi)
- Cardiff-by-the-Sea Hotels (17.11 mi)
- Coronado Island Hotels (8.08 mi)
- El Cajon Hotels (10.25 mi)
- Solana Beach Hotels (15.09 mi)
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