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Independent in Central San Diego

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Featured Central San Diego Independent

Lafayette Hotel & Club
Lafayette Hotel & Club
4 out of 5
2223 El Cajon Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Lafayette Hotel & Club
Handlery Hotel
Handlery Hotel
3.5 out of 5
950 Hotel Cir N, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Handlery Hotel
California Suites Hotel
California Suites Hotel
2 out of 5
5415 Clairemont Mesa Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
California Suites Hotel
The Atwood Hotel San Diego - SeaWorld/Zoo
The Atwood Hotel San Diego - SeaWorld/Zoo
3 out of 5
1201 Hotel Circle South, Mission Valley, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf hotel in San Diego. Enjoy free WiFi, a 24-hour front desk, and a snack bar/deli. Our guests praise the pool and the restaurant in our ...
The Atwood Hotel San Diego - SeaWorld/Zoo
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
4 out of 5
875 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Legacy Resort Hotel & Spa
E-Z 8 Motel Old Town
E-Z 8 Motel Old Town
2.5 out of 5
4747 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
E-Z 8 Motel Old Town
Pleasant Inn
Pleasant Inn
2.5 out of 5
5550 Clairemont Mesa Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
Riverleaf Inn Mission Valley
Riverleaf Inn Mission Valley
2.5 out of 5
San Diego
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
Riverleaf Inn Mission Valley
Old Town Western Inn & Suites
Old Town Western Inn & Suites
2.5 out of 5
3889 Arista St, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the clean ...
Old Town Western Inn & Suites
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 out of 5
819 University Ave, San Diego, CA
Stay at this aparthotel in San Diego. Enjoy free WiFi, parking (surcharge), and laundry facilities. Popular attractions San Diego Zoo and Balboa Park are located ...
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Abpopa Hillcrest
Abpopa Hillcrest
3 out of 5
3776 Fourth Ave, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
Abpopa Hillcrest
Berkshire Motor Hotel
Berkshire Motor Hotel
2.5 out of 5
2502 El Cajon Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Berkshire Motor Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Independent hotels in Central San Diego

You’ve already taken the guesswork out of your next vacation. You know you want a Independent hotel in Central San Diego. What can you say? You like their style, they’re in a good part of Central San Diego, and they never let you down. New bar in town? You’re the first one to check it out. Spiciest item on the menu? You can take the heat. But even the best gamblers hedge their bets. No matter how crazy good your trip is, you want something familiar waiting for you at the end of the day.

All in a name

We all have favorites. There’s nothing wrong with knowing what you like. You like to stay at Independent near , Central San Diego to do the tourist thing (because sometimes it is fun) and then hit up the places that aren’t on the map. And no matter what fun you get into, you have Independent hotels with their comfy beds and thoughtful amenities waiting to tuck you in.

As you like it

Have a price you want to stick to, so you can paint the town red? Maybe, it’s all about the hotel features. Who couldn’t use a hot tub? Pick your pleasure by:

  • Hotwire Hot Rate: Grab the Independent hotel in Central San Diego at an absolute steal. After you book it, we’ll tell you the hotel name. You might nab that 4-star hotel for a 2-star price.
  • Price: How low can we go? Quite low in fact. Check out our prices per night, starting at $84.
  • Amenities: Grab a cocktail at the lounge and maybe wander upstairs to the rooftop terrace—all the stuff that makes a great vacay.

You’ve already done the hard part—figuring out where you want to stay. Now it’s time to use the money you saved to let the real fun begin. Underground shows? Off-beat attractions? Rooftop escapes? The choice is yours. The only thing wonderfully predictable about this trip is the Independent room you’ll be staying in.