Hotels Near
Little Italy

Check Last Minute Little Italy Hotel Deals

Tonight Nov 2 - Nov 3Next weekend Nov 7 - Nov 9

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Little Italy Hotels

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St, San Diego, CA
Fully refundable
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8/10 Very Good! (1,145 reviews)
Balcony view and healthy breakfast! Excellent customer service!

Reviewed on Oct 28, 2025

Courtyard by Marriott San Diego Downtown Little Italy
Hilton Garden Inn San Diego Downtown/Bayside

Hilton Garden Inn San Diego Downtown/Bayside

3.5 out of 5
2137 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (1,176 reviews)
Clean room. Very nice staff

Reviewed on Oct 28, 2025

Hilton Garden Inn San Diego Downtown/Bayside
Urban Boutique Hotel

Urban Boutique Hotel

3 out of 5
1654 Columbia Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,281 reviews)
The staff was absolutely lovely and very helpful the entire length of our stay. The room was clean, cute & very comfortable. We could not have picked a better spot, staying around the corner from the main plaza in Little Italy was the perfect vibe for a romantic trip, not to mention a short walk ...

Reviewed on Oct 26, 2025

Urban Boutique Hotel
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

2.5 out of 5
San Diego
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (2,217 reviews)
Clean, close to public transit, a park, and harbor front, super restaurants walking distance, pleasant staff, great free breakfast

Reviewed on Oct 29, 2025

Hampton Inn San Diego-Downtown
La Pensione Hotel

La Pensione Hotel

3 out of 5
606 West Date Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
8.6/10 Excellent! (1,919 reviews)
Clean room and nice view of the street. Exceptional staff at all times. Tookcare of any and every issue that I had, which were few. When I return to San Diego I already know where I'm staying.

Reviewed on Oct 28, 2025

La Pensione Hotel
Porto Vista Hotel Downtown

Porto Vista Hotel Downtown

3.5 out of 5
1835 Columbia St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
6.6/10 (1,184 reviews)
Very kind personal

Reviewed on Oct 27, 2025

Porto Vista Hotel Downtown
Homewood Suites by Hilton San Diego Downtown/Bayside

Homewood Suites by Hilton San Diego Downtown/Bayside

3.5 out of 5
2137 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,026 reviews)
Our room was clean, front desk staff was not that helpful… pool area is small.

Reviewed on Oct 27, 2025

Homewood Suites by Hilton San Diego Downtown/Bayside
Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel

2.5 out of 5
1736 State St, San Diego, CA
Stay at this aparthotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Port of San Diego and USS Midway Museum ...
8/10 Very Good! (97 reviews)
The staff was very courteous and helpful. Rom was small, but very clean and met the needs that we had. I was a little disappointed. I could not check in earlier, but it all worked out.

Reviewed on Oct 31, 2025

Little Italy Inn - Limited Service Apart Hotel
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8/10 Very Good! (2,107 reviews)
Didn’t use the pool but area very well maintained Only negative comment Saturday morning went to the front desk to have only our beds made . Came back to the hotel at 7:00 pm beds were not made very disappointing I did call when I came back to my room the front desk so the supervisor of my housekeeper ...

Reviewed on Oct 28, 2025

Hilton San Diego Mission Valley
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Mission ...
9/10 Wonderful! (207 reviews)
A nice, clean Hampton Inn. Everything that you would expect

Reviewed on Oct 27, 2025

Hampton Inn & Suites by Hilton San Diego SeaWorld
Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,003 reviews)
The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel.

Reviewed on Oct 22, 2025

Pendry San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...
8.8/10 Excellent! (3,029 reviews)
Staff was great. My only two complaint is. The main lobby is over powering with some type of air freshener. And also our balcony door did not lock. It is very noisy at night but you are in down town where all the night life is. It’s a nice stay for sure.

Reviewed on Oct 26, 2025

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Little Italy

San Diego is a city that has a lot going on, but you have your sights set on Little Italy. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Little Italy has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Little Italy hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Little Italy underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Little Italy city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Little Italy cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Little Italy at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $122
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Little Italy hotel you want, book it, and never look back. Because your great escape is ahead of you.