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Featured Little Italy Family Hotels

Homewood Suites by Hilton San Diego Downtown/Bayside
2137 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our ...

Residence Inn by Marriott San Diego Downtown
1747 Pacific Hwy, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...

Urban Boutique Hotel
1654 Columbia Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a 24-hour front desk, and a 24-hour business center. Our guests praise the helpful ...

Hilton Garden Inn San Diego Downtown/Bayside
2137 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff ...

Harborview Inn & Suites San Diego Harbor
550 West Grape St, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...

Hampton Inn San Diego-Downtown
San Diego
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...

Porto Vista Hotel Downtown
1835 Columbia St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...

The Pacific
1655 Pacific Hwy, San Diego, CA
Stay at this hotel in San Diego. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Popular attractions Port of San Diego and USS Midway Museum ...

The Little Italy Hotel Downtown San Diego
1646 Front St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...

Motel 6 San Diego Airport - Harbor
2353 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this motel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...

La Pensione Hotel
606 West Date Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Little Italy

Homewood Suites by Hilton San Diego Downtown/Bayside
2137 Pacific Highway, San Diego, CA
Stay at this 3.5-star hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our ...
8.4/10 Very Good! (1,002 reviews)
Great location, very helpful people!
"Everything was good.. family upstairs was a little noisy but Nicholas handled it. Also one of the elevators was out so little bit of waiting but otherwise we really enjoyed our stay!!"
Reviewed on Mar 16, 2025

Hilton Garden Inn San Diego Downtown/Bayside
2137 Pacific Highway, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,049 reviews)
"Just a couple blocks from the Bayfront. Easy to get to the airport and most attractions! Staff was great with our little one. We would definitely stay again."
Reviewed on Mar 23, 2025

The Pacific
1655 Pacific Hwy, San Diego, CA
Stay at this hotel in San Diego. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Popular attractions Port of San Diego and USS Midway Museum ...
6/10 (396 reviews)
"We never went to The Pacific!! We got a text from Expedia telling us the Pacific was closed due to renovations and we were booked at Motel 6 Chula Vista. We paid $50. to take us there only to find out we did not have a reservation. So Expedia has our $274. and we have no accommodations. We rebooked ..."
Reviewed on Oct 8, 2022
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Little Italy

Hampton Inn San Diego-Downtown
San Diego
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...

Hilton Garden Inn San Diego Downtown/Bayside
2137 Pacific Highway, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff ...

Homewood Suites by Hilton San Diego Downtown/Bayside
2137 Pacific Highway, San Diego, CA
Stay at this 3.5-star hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Beach Hotels in Little Italy
- Hotels with a Pool in Little Italy
- Apartment Hotel in Little Italy
- Historic Hotels in Little Italy
- Hotels with Hot Tubs in Little Italy
- Hotels with Free Parking in Little Italy
- Romantic Hotels in Little Italy
- Luxury Hotels in Little Italy
- Pet-friendly Hotels in Little Italy
- Resorts & Hotels with Spas in Little Italy
Top Points of Interests in Little Italy
- Hotels near Waterfront Park
- Hotels near Maritime Museum of San Diego
- Hotels near Star of India
- Hotels near Our Lady of the Rosary Catholic Church
- Hotels near Firehouse Museum
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Petco Park
- Hotels near Mission Beach
- Hotels near San Diego State University
- Hotels near Hotel Circle
- Hotels near Marine Corps Recruit Depot
- Hotels near Port of San Diego
- Hotels near Naval Base San Diego
- Hotels near Coronado Beach
- Hotels near USS Midway Museum
- Hotels near University of San Diego
Cities near Little Italy
- San Diego Hotels (0.81 mi)
- La Jolla Hotels (9.5 mi)
- Coronado Hotels (2.77 mi)
- Del Mar Hotels (16.99 mi)
- Chula Vista Hotels (7.69 mi)
- Coronado Island Hotels (2.45 mi)
- El Cajon Hotels (13.01 mi)
- Solana Beach Hotels (19.31 mi)
- Southern California Hotels (78.28 mi)
- National City Hotels (5.24 mi)
- La Mesa Hotels (9.06 mi)
- Rancho Santa Fe Hotels (20.51 mi)
- Imperial Beach Hotels (10.26 mi)
- Poway Hotels (18.21 mi)
- San Ysidro Hotels (14.03 mi)
- Santee Hotels (13.85 mi)
- Bonita Hotels (9.09 mi)
- Spring Valley Hotels (10.06 mi)
- Lakeside Hotels (17.08 mi)
- San Diego Coast Hotels (8.3 mi)
Car Rentals Near Little Italy
- Car rentals in San Diego
- Car rentals in La Jolla
- Car rentals in Coronado
- Car rentals in Del Mar
- Car rentals in Chula Vista
- Car rentals in Coronado Island
- Car rentals in El Cajon
- Car rentals in Solana Beach
- Car rentals in Southern California
- Car rentals in National City
- Car rentals in La Mesa
- Car rentals in Rancho Santa Fe
- Car rentals in Imperial Beach
- Car rentals in Poway
- Car rentals in San Ysidro
- Car rentals in Santee
Top Family Hotel Destinations
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- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
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- Birmingham Family Hotels
Top Booked Hotels in Little Italy
- The Little Italy Hotel Downtown San Diego
- Hampton Inn San Diego-Downtown
- La Pensione Hotel
- Homewood Suites by Hilton San Diego Downtown/Bayside
- Hilton Garden Inn San Diego Downtown/Bayside
- San Diego Marriott La Jolla
- The Dana on Mission Bay
- Wyndham San Diego Bayside
- San Diego Mission Bay Resort
- Best Western Seven Seas
- Paradise Point Resort & Spa
- Comfort Inn Sea World Area
- Humphreys Half Moon Inn
- Handlery Hotel
- Loews Coronado Bay Resort