Search for Cheap Deals onLuxury Hotels in Little Italy
Check Last Minute Little Italy Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured Luxury Little Italy

Harborview Inn & Suites San Diego Harbor
550 West Grape St, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...

Urban Boutique Hotel
1654 Columbia Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a 24-hour front desk, and a 24-hour business center. Our guests praise the helpful ...

Motel 6 San Diego Airport - Harbor
2353 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this motel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...

La Pensione Hotel
606 West Date Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...

Porto Vista Hotel Downtown
1835 Columbia St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...

Hampton Inn San Diego-Downtown
San Diego
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...

The Pacific
1655 Pacific Hwy, San Diego, CA
Stay at this hotel in San Diego. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Popular attractions Port of San Diego and USS Midway Museum ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Little Italy
- Beach Hotels in Little Italy
- Hotels with a Pool in Little Italy
- Apartment Hotel in Little Italy
- Family Hotels in Little Italy
- Historic Hotels in Little Italy
- Hotels with Hot Tubs in Little Italy
- Hotels with Free Parking in Little Italy
- Romantic Hotels in Little Italy
- Pet-friendly Hotels in Little Italy
- Resorts & Hotels with Spas in Little Italy
Top Points of Interests in Little Italy
- Hotels near Waterfront Park
- Hotels near Maritime Museum of San Diego
- Hotels near Star of India
- Hotels near Our Lady of the Rosary Catholic Church
- Hotels near Firehouse Museum
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Mission Beach
- Hotels near Petco Park
- Hotels near San Diego State University
- Hotels near Hotel Circle
- Hotels near Naval Base San Diego
- Hotels near USS Midway Museum
- Hotels near Marine Corps Recruit Depot
- Hotels near Port of San Diego
- Hotels near Coronado Beach
- Hotels near Hotel del Coronado
Cities near Little Italy
- San Diego Hotels (0.81 mi)
- La Jolla Hotels (9.5 mi)
- Del Mar Hotels (16.99 mi)
- Coronado Hotels (2.77 mi)
- Chula Vista Hotels (7.69 mi)
- Coronado Island Hotels (2.45 mi)
- El Cajon Hotels (13.01 mi)
- Solana Beach Hotels (19.31 mi)
- Southern California Hotels (78.28 mi)
- National City Hotels (5.24 mi)
- La Mesa Hotels (9.06 mi)
- Rancho Santa Fe Hotels (20.51 mi)
- Imperial Beach Hotels (10.26 mi)
- Poway Hotels (18.21 mi)
- San Ysidro Hotels (14.03 mi)
- Santee Hotels (13.85 mi)
- Spring Valley Hotels (10.06 mi)
- Lakeside Hotels (17.08 mi)
- Bonita Hotels (9.09 mi)
- San Diego Coast Hotels (8.3 mi)
Car Rentals Near Little Italy
- Car rentals in San Diego
- Car rentals in La Jolla
- Car rentals in Del Mar
- Car rentals in Coronado
- Car rentals in Chula Vista
- Car rentals in Coronado Island
- Car rentals in El Cajon
- Car rentals in Solana Beach
- Car rentals in Southern California
- Car rentals in National City
- Car rentals in La Mesa
- Car rentals in Rancho Santa Fe
- Car rentals in Imperial Beach
- Car rentals in Poway
- Car rentals in San Ysidro
- Car rentals in Santee
Top Luxury Hotel Destinations
- Amarillo Luxury Hotels
- Sioux Falls Luxury Hotels
- Fort Wayne Luxury Hotels
- South Padre Island Luxury Hotels
- Cheyenne Luxury Hotels
- Corpus Christi Luxury Hotels
- Gettysburg Luxury Hotels
- Fresno Luxury Hotels
- Fayetteville Luxury Hotels
- Springfield Luxury Hotels
- Flagstaff Luxury Hotels
- Tuscaloosa Luxury Hotels
- Toledo Luxury Hotels
- Traverse City Luxury Hotels
- Twin Falls Luxury Hotels
- Scranton Luxury Hotels
- Columbia Luxury Hotels
- Catalina Island Luxury Hotels
- Shreveport Luxury Hotels
- Tallahassee Luxury Hotels
Top Booked Hotels in Little Italy
- Urban Boutique Hotel
- La Pensione Hotel
- Hilton Garden Inn San Diego Downtown/Bayside
- Homewood Suites by Hilton San Diego Downtown/Bayside
- The Dana on Mission Bay
- Omni San Diego Hotel
- Hard Rock Hotel San Diego
- Hyatt Regency Mission Bay Spa and Marina
- Comfort Inn Sea World Area
- Wyndham San Diego Bayside
- Sheraton Mission Valley San Diego Hotel