Hotels Near
Little Italy

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Little Italy Hotels

The Little Italy Hotel Downtown San Diego
The Little Italy Hotel Downtown San Diego
4 out of 5
1646 Front St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,026 reviews)
"All good"

Reviewed on Jun 28, 2025

The Little Italy Hotel Downtown San Diego
La Pensione Hotel
La Pensione Hotel
3 out of 5
606 West Date Street, San Diego, CA
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
8.4/10 Very Good! (1,766 reviews)
"Cute room and hotel. Was able to use the parking under the hotel which was convenient. Reminds you of an older classy hotel. Coffee shop was great!"

Reviewed on Jun 30, 2025

La Pensione Hotel
Little Italy Inn - Limited Service Apart Hotel
Little Italy Inn - Limited Service Apart Hotel
2.5 out of 5
1736 State St, San Diego, CA
Stay at this aparthotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Port of San Diego and USS Midway Museum ...
8.6/10 Excellent! (8 reviews)
"This was the first time staying in Little Italy and I enjoyed the experience. The place, including the kitchen was spotless. I enjoyed being able to cook my own meals 😁"

Reviewed on Jun 21, 2025

Little Italy Inn - Limited Service Apart Hotel
Hampton Inn San Diego-Downtown
Hampton Inn San Diego-Downtown
2.5 out of 5
San Diego
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,994 reviews)
"Su ubicación es muy céntrica y el staff fue muy amable."

Reviewed on Jun 30, 2025

Hampton Inn San Diego-Downtown
Homewood Suites by Hilton San Diego Downtown/Bayside
Homewood Suites by Hilton San Diego Downtown/Bayside
3.5 out of 5
2137 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our ...
8.4/10 Very Good! (1,007 reviews)
"The property was spacious and provided games for the kids, I like that it is family friendly."

Reviewed on Jun 25, 2025

Homewood Suites by Hilton San Diego Downtown/Bayside
Urban Boutique Hotel
Urban Boutique Hotel
3 out of 5
1654 Columbia Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and ...
8.4/10 Very Good! (1,183 reviews)
"The staff were really friendly and helpful, especially Macie! She went above and beyond to fix my IPhone!! Thank you Macie , I really appreciate you doing that!! Liked the location. It’s in the center of Little Italy, very convenient. The room has a nice view and comfortable bed. Just one thing I ..."

Reviewed on Jun 23, 2025

Urban Boutique Hotel
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,716 reviews)
"we had a bay view which was excellent"

Reviewed on Jul 2, 2025

Wyndham San Diego Bayside
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
4 out of 5
333 W Harbor Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,723 reviews)
"Excellent"

Reviewed on Jul 3, 2025

Marriott Marquis San Diego Marina
Handlery Hotel
Handlery Hotel
3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,840 reviews)
Greed
"Paying 24 dollars a night for parking is a total rip off!! They are making some serious cash charging that. Greedy owners!!"

Reviewed on Jun 29, 2025

Handlery Hotel
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,790 reviews)
"Great experience and great location"

Reviewed on Jun 27, 2025

Manchester Grand Hyatt San Diego
San Diego Marriott La Jolla
San Diego Marriott La Jolla
4 out of 5
4240 La Jolla Village Dr, La Jolla, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
8.4/10 Very Good! (1,871 reviews)
"Great location and very comfortable hotel"

Reviewed on Jul 1, 2025

San Diego Marriott La Jolla
DoubleTree by Hilton San Diego - Del Mar
DoubleTree by Hilton San Diego - Del Mar
4 out of 5
11915 El Camino Real, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
7.8/10 Good! (1,203 reviews)
"Good stay"

Reviewed on Jun 29, 2025

DoubleTree by Hilton San Diego - Del Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Little Italy

San Diego is a city that has a lot going on, but you have your sights set on Little Italy. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Little Italy has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Little Italy hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Little Italy underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Little Italy city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Little Italy cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Little Italy at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Little Italy hotel you want, book it, and never look back. Because your great escape is ahead of you.