Hotels Near
Little Italy

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Featured Little Italy Hotels

The Little Italy Hotel Downtown San Diego

The Little Italy Hotel Downtown San Diego

4 out of 5
1646 Front St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,004 reviews)
"Great property"

Reviewed on Jul 15, 2025

The Little Italy Hotel Downtown San Diego
Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel

2.5 out of 5
1736 State St, San Diego, CA
Stay at this aparthotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Port of San Diego and USS Midway Museum ...
7.6/10 Good! (16 reviews)
Convenient location
"The location is great, right in the heart of little Italy, and walking distance to a lot of places. The room itself was clean, but quite small. The air conditioner really struggled to keep up, and the power went off and back on at least 5x while we were in the room over a 2 night stay."

Reviewed on Jul 2, 2025

Little Italy Inn - Limited Service Apart Hotel
Hilton Garden Inn San Diego Downtown/Bayside

Hilton Garden Inn San Diego Downtown/Bayside

3.5 out of 5
2137 Pacific Highway, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,063 reviews)
"Loved the lounge area"

Reviewed on Jul 15, 2025

Hilton Garden Inn San Diego Downtown/Bayside
La Pensione Hotel

La Pensione Hotel

3 out of 5
606 West Date Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
8.4/10 Very Good! (1,784 reviews)
"Quiet."

Reviewed on Jul 14, 2025

La Pensione Hotel
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

2.5 out of 5
San Diego
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (2,027 reviews)
"Wonderful location and friendly staff. The parking garage fills up and has small spaces. They are working on 2 of the 3 elevators so we had to use the stairs most of the time. The stairs are accessed by walking through the employee areas, which confused the guests. It will be a nice place to stay ..."

Reviewed on Jul 14, 2025

Hampton Inn San Diego-Downtown
Urban Boutique Hotel

Urban Boutique Hotel

3 out of 5
1654 Columbia Street, San Diego, CA
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and ...
8.4/10 Very Good! (1,204 reviews)
"Great staff, very accommodating. No problem with room amenities."

Reviewed on Jul 13, 2025

Urban Boutique Hotel
Homewood Suites by Hilton San Diego Downtown/Bayside

Homewood Suites by Hilton San Diego Downtown/Bayside

3.5 out of 5
2137 Pacific Highway, San Diego, CA
Stay at this 3.5-star hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,005 reviews)
"Did not like the mandatory parking fee."

Reviewed on Jul 2, 2025

Homewood Suites by Hilton San Diego Downtown/Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,870 reviews)
Nice place great value
"Great spot for the price point. A bit dayed but clean. Nice pool and pool bar and grounds are nice. A great value"

Reviewed on Jul 14, 2025

Handlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,735 reviews)
"Such a beautiful hotel !"

Reviewed on Jul 15, 2025

Wyndham San Diego Bayside
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,751 reviews)
"Overall a good experience. Room doors bang loudly."

Reviewed on Jul 14, 2025

Marriott Marquis San Diego Marina
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
8.8/10 Excellent! (2,762 reviews)
"Great"

Reviewed on Jul 14, 2025

Manchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,568 reviews)
"Love The Dana! We have stayed 2 times now. Very clean. Great service and food/drinks. 10 min walk to the beach. Love the staff and variety at the gift shop. Convenient shuttle to Sea World. 15 min drive to San Diego Zoo. Definitely coming back!"

Reviewed on Jul 12, 2025

The Dana on Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Little Italy

San Diego is a city that has a lot going on, but you have your sights set on Little Italy. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Little Italy has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Little Italy hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Little Italy underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Little Italy city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Little Italy cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Little Italy at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $100
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Little Italy hotel you want, book it, and never look back. Because your great escape is ahead of you.