Search Cheap Flights to
La Mesa

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La Mesa Flights as Low as $72

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Aug 30 - Thu, Sep 4
SFO
San Francisco Intl.
SAN
San Diego Intl.
$72 Roundtrip, found 4 hours ago
$72
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, Aug 30 from San Francisco Intl. to San Diego Intl., returning Thu, Sep 4, priced at $72 found 4 hours ago
Frontier Airlines
Sat, Oct 18 - Sat, Oct 18
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$74 Roundtrip, found 2 days ago
$74
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Oct 18 from Sky Harbor Intl. to San Diego Intl., returning Sat, Oct 18, priced at $74 found 2 days ago
Frontier Airlines
Sat, Aug 30 - Thu, Sep 4
SFO
San Francisco Intl.
SAN
San Diego Intl.
$75 Roundtrip, found 4 hours ago
$75
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, Aug 30 from San Francisco Intl. to San Diego Intl., returning Thu, Sep 4, priced at $75 found 4 hours ago
Alaska Airlines
Tue, Aug 26 - Tue, Sep 9
SFO
San Francisco Intl.
SAN
San Diego Intl.
$77 Roundtrip, found 4 hours ago
$77
Roundtrip
found 4 hours ago
Select Alaska Airlines flight, departing Tue, Aug 26 from San Francisco Intl. to San Diego Intl., returning Tue, Sep 9, priced at $77 found 4 hours ago
United
Tue, Aug 26 - Tue, Sep 9
SFO
San Francisco Intl.
SAN
San Diego Intl.
$77 Roundtrip, found 4 hours ago
$77
Roundtrip
found 4 hours ago
Select United flight, departing Tue, Aug 26 from San Francisco Intl. to San Diego Intl., returning Tue, Sep 9, priced at $77 found 4 hours ago
Frontier Airlines
Thu, Sep 4 - Sat, Sep 6
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$78 Roundtrip, found 5 hours ago
$78
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Thu, Sep 4 from Sky Harbor Intl. to San Diego Intl., returning Sat, Sep 6, priced at $78 found 5 hours ago
Frontier Airlines
Tue, Aug 12 - Thu, Aug 14
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$80 Roundtrip, found 1 day ago
$80
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Aug 12 from Sky Harbor Intl. to San Diego Intl., returning Thu, Aug 14, priced at $80 found 1 day ago
Frontier Airlines
Sun, Aug 31 - Wed, Sep 3
SFO
San Francisco Intl.
SAN
San Diego Intl.
$84 Roundtrip, found 1 day ago
$84
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Aug 31 from San Francisco Intl. to San Diego Intl., returning Wed, Sep 3, priced at $84 found 1 day ago
Hawaiian Airlines
Sat, Sep 27 - Sat, Sep 27
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$97 Roundtrip, found 21 hours ago
$97
Roundtrip
found 21 hours ago
Select Hawaiian Airlines flight, departing Sat, Sep 27 from Sky Harbor Intl. to San Diego Intl., returning Sat, Sep 27, priced at $97 found 21 hours ago
American Airlines
Thu, Sep 4 - Sat, Sep 6
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$99 Roundtrip, found 5 hours ago
$99
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Sep 4 from Sky Harbor Intl. to San Diego Intl., returning Sat, Sep 6, priced at $99 found 5 hours ago
American Airlines
Mon, Sep 22 - Fri, Oct 3
PHX
Sky Harbor Intl.
CLD
McClellan-Palomar
$107 Roundtrip, found 11 hours ago
$107
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, Sep 22 from Sky Harbor Intl. to McClellan-Palomar, returning Fri, Oct 3, priced at $107 found 11 hours ago
Bargain Flight
Tue, Oct 21 - Wed, Oct 29
PAE
Seattle Paine Field Intl. Airport
SAN
San Diego Intl.
$157 Roundtrip, found 12 hours ago
$157
Roundtrip
found 12 hours ago
Select Bargain Flight flight, departing Tue, Oct 21 from Seattle Paine Field Intl. Airport to San Diego Intl., returning Wed, Oct 29, priced at $157 found 12 hours ago
American Airlines
Tue, Sep 2 - Wed, Sep 3
SFO
San Francisco Intl.
CLD
McClellan-Palomar
$159 Roundtrip, found 5 hours ago
$159
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Sep 2 from San Francisco Intl. to McClellan-Palomar, returning Wed, Sep 3, priced at $159 found 5 hours ago
Spirit Airlines
Tue, Aug 5 - Mon, Aug 11
IAH
George Bush Intercontinental
SAN
San Diego Intl.
$173 Roundtrip, found 2 days ago
$173
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Tue, Aug 5 from George Bush Intercontinental to San Diego Intl., returning Mon, Aug 11, priced at $173 found 2 days ago
Delta
Tue, Oct 21 - Wed, Oct 22
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$177 Roundtrip, found 15 hours ago
$177
Roundtrip
found 15 hours ago
Select Delta flight, departing Tue, Oct 21 from Sky Harbor Intl. to San Diego Intl., returning Wed, Oct 22, priced at $177 found 15 hours ago
American Airlines
Tue, Sep 2 - Thu, Sep 11
IAH
George Bush Intercontinental
CLD
McClellan-Palomar
$230 Roundtrip, found 6 days ago
$230
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Sep 2 from George Bush Intercontinental to McClellan-Palomar, returning Thu, Sep 11, priced at $230 found 6 days ago

Cheap Flights to La Mesa

Fall in love at first flight with your vacation to La Mesa by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to La Mesa on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in La Mesa, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to La Mesa

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to La Mesa with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SAN airport.

What is the cheapest month to fly to La Mesa?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to La Mesa are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to La Mesa?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to La Mesa.

What airport is best to fly into La Mesa?

When you’re planning your trip to La Mesa, convenience is the name of the game. Luckily, La Mesa Gillespie Field Airport is nearby so you can deplane and get going on checking off everything on your La Mesa must-do list.

How much are flights to La Mesa?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to La Mesa on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $72, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to La Mesa?

The trick to saving a stack of cash on your flight to La Mesa? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $72 right now, why wait?

La Mesa Flight Information
Destination airport
San Diego Intl.
Destination airport IATA code
SAN
Roundtrip price
$72

Last Minute Hotel Deals in La Mesa

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,899 reviews)
"Amazing hotel clean and the pool was so nice with restaurants very good"

Reviewed on Jul 23, 2025

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Handlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,750 reviews)
"great location"

Reviewed on Jul 21, 2025

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Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,788 reviews)
"Enjoyed my stay at this place. Friendly and courteous staff"

Reviewed on Jul 21, 2025

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Manchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,582 reviews)
Perfect Staycation Hotel
"This is our 4th time staying at the Dana and we love it! Such beautiful views and even tho a bit pricey, my kids love it has 2 pools with 2 spas and movie nights! The staff are great and it’s very quiet and home feeling . We will be back in a couple of months !"

Reviewed on Jul 22, 2025

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The Dana on Mission Bay
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,770 reviews)
"Great hotel, everything nice"

Reviewed on Jul 19, 2025

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Marriott Marquis San Diego Marina
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8/10 Very Good! (1,301 reviews)
"We liked the hotel, very clean. But we didn’t like that our AC did not work. We told the front desk 3 times and the maintenance guy was supposed to fix it. but he never showed up. That room was hot. I told the front desk again when I checked out and they did not charge me for parking for my inconvenience. ..."

Reviewed on Jul 21, 2025

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DoubleTree by Hilton San Diego - Del Mar
The Dextro Hotel, BW Premier Collection

The Dextro Hotel, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
7.6/10 Good! (1,024 reviews)
"In a good place downtown"

Reviewed on Jul 20, 2025

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The Dextro Hotel, BW Premier Collection
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4 out of 5
1 Park Blvd, San Diego, CA
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (1,609 reviews)
"From the moment we arrived we were welcomed. Our housekeeper was extremely helpful when we needed extra trash bags. We let her know the one we had was damaged. She fixed the problem right away. Room service was quick. I love that check out was done by text and it was quick and on point. Great ..."

Reviewed on Jul 23, 2025

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Hilton San Diego Bayfront
See all 8,107 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.