Search Cheap Flights to
La Mesa

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La Mesa Flights as Low as $72

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Aug 30 - Thu, Sep 4
SFO
San Francisco Intl.
SAN
San Diego Intl.
$72 Roundtrip, found 1 day ago
$72
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Aug 30 from San Francisco Intl. to San Diego Intl., returning Thu, Sep 4, priced at $72 found 1 day ago
Frontier Airlines
Sat, Oct 18 - Sat, Oct 18
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$74 Roundtrip, found 2 days ago
$74
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Oct 18 from Sky Harbor Intl. to San Diego Intl., returning Sat, Oct 18, priced at $74 found 2 days ago
Frontier Airlines
Sat, Aug 30 - Thu, Sep 4
SFO
San Francisco Intl.
SAN
San Diego Intl.
$75 Roundtrip, found 1 day ago
$75
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Aug 30 from San Francisco Intl. to San Diego Intl., returning Thu, Sep 4, priced at $75 found 1 day ago
Alaska Airlines
Tue, Sep 2 - Tue, Sep 9
SFO
San Francisco Intl.
SAN
San Diego Intl.
$77 Roundtrip, found 8 hours ago
$77
Roundtrip
found 8 hours ago
Select Alaska Airlines flight, departing Tue, Sep 2 from San Francisco Intl. to San Diego Intl., returning Tue, Sep 9, priced at $77 found 8 hours ago
United
Tue, Sep 2 - Tue, Sep 9
SFO
San Francisco Intl.
SAN
San Diego Intl.
$77 Roundtrip, found 8 hours ago
$77
Roundtrip
found 8 hours ago
Select United flight, departing Tue, Sep 2 from San Francisco Intl. to San Diego Intl., returning Tue, Sep 9, priced at $77 found 8 hours ago
Alaska Airlines
Sun, Aug 31 - Thu, Sep 4
SFO
San Francisco Intl.
SAN
San Diego Intl.
$87 Roundtrip, found 1 day ago
$87
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Sun, Aug 31 from San Francisco Intl. to San Diego Intl., returning Thu, Sep 4, priced at $87 found 1 day ago
Hawaiian Airlines
Sat, Sep 27 - Sat, Sep 27
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$97 Roundtrip, found 1 day ago
$97
Roundtrip
found 1 day ago
Select Hawaiian Airlines flight, departing Sat, Sep 27 from Sky Harbor Intl. to San Diego Intl., returning Sat, Sep 27, priced at $97 found 1 day ago
American Airlines
Tue, Oct 21 - Wed, Oct 22
PHX
Sky Harbor Intl.
SAN
San Diego Intl.
$97 Roundtrip, found 21 hours ago
$97
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Tue, Oct 21 from Sky Harbor Intl. to San Diego Intl., returning Wed, Oct 22, priced at $97 found 21 hours ago
American Airlines
Thu, Sep 4 - Sat, Sep 6
PHX
Sky Harbor Intl.
CLD
McClellan-Palomar
$99 Roundtrip, found 1 hour ago
$99
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Sep 4 from Sky Harbor Intl. to McClellan-Palomar, returning Sat, Sep 6, priced at $99 found 1 hour ago
American Airlines
Tue, Sep 2 - Tue, Sep 9
SFO
San Francisco Intl.
CLD
McClellan-Palomar
$159 Roundtrip, found 8 hours ago
$159
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Sep 2 from San Francisco Intl. to McClellan-Palomar, returning Tue, Sep 9, priced at $159 found 8 hours ago
Spirit Airlines
Wed, Sep 10 - Thu, Sep 11
DTW
Detroit Metropolitan Wayne County
SAN
San Diego Intl.
$166 Roundtrip, found 5 days ago
$166
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Wed, Sep 10 from Detroit Metropolitan Wayne County to San Diego Intl., returning Thu, Sep 11, priced at $166 found 5 days ago
Delta
Tue, Sep 2 - Tue, Sep 9
SFO
San Francisco Intl.
SAN
San Diego Intl.
$177 Roundtrip, found 8 hours ago
$177
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Sep 2 from San Francisco Intl. to San Diego Intl., returning Tue, Sep 9, priced at $177 found 8 hours ago
Spirit Airlines
Thu, Aug 28 - Thu, Sep 4
MIA
Miami Intl.
SAN
San Diego Intl.
$221 Roundtrip, found 2 days ago
$221
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Thu, Aug 28 from Miami Intl. to San Diego Intl., returning Thu, Sep 4, priced at $221 found 2 days ago
American Airlines
Thu, Aug 28 - Thu, Sep 4
MIA
Miami Intl.
CLD
McClellan-Palomar
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Aug 28 from Miami Intl. to McClellan-Palomar, returning Thu, Sep 4, priced at $279 found 2 days ago
JetBlue Airways
Fri, Oct 31 - Sat, Nov 8
DTW
Detroit Metropolitan Wayne County
SAN
San Diego Intl.
$291 Roundtrip, found 1 day ago
$291
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Fri, Oct 31 from Detroit Metropolitan Wayne County to San Diego Intl., returning Sat, Nov 8, priced at $291 found 1 day ago
American Airlines
Thu, Sep 11 - Sun, Sep 14
DTW
Detroit Metropolitan Wayne County
CLD
McClellan-Palomar
$361 Roundtrip, found 5 days ago
$361
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Sep 11 from Detroit Metropolitan Wayne County to McClellan-Palomar, returning Sun, Sep 14, priced at $361 found 5 days ago

Cheap Flights to La Mesa

Fall in love at first flight with your vacation to La Mesa by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to La Mesa on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in La Mesa, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to La Mesa

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to La Mesa with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SAN airport.

What is the cheapest month to fly to La Mesa?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to La Mesa are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to La Mesa?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to La Mesa.

What airport is best to fly into La Mesa?

When you’re planning your trip to La Mesa, convenience is the name of the game. Luckily, La Mesa Gillespie Field Airport is nearby so you can deplane and get going on checking off everything on your La Mesa must-do list.

How much are flights to La Mesa?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to La Mesa on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $72, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to La Mesa?

The trick to saving a stack of cash on your flight to La Mesa? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $72 right now, why wait?

La Mesa Flight Information
Destination airport
San Diego Intl.
Destination airport IATA code
SAN
Roundtrip price
$72

Last Minute Hotel Deals in La Mesa

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,899 reviews)
"Amazing hotel clean and the pool was so nice with restaurants very good"

Reviewed on Jul 23, 2025

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Handlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,781 reviews)
"Front desk very helpful. Check in easy. Nice stay"

Reviewed on Jul 24, 2025

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Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,796 reviews)
"Outstanding"

Reviewed on Jul 24, 2025

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Manchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,582 reviews)
Perfect Staycation Hotel
"This is our 4th time staying at the Dana and we love it! Such beautiful views and even tho a bit pricey, my kids love it has 2 pools with 2 spas and movie nights! The staff are great and it’s very quiet and home feeling . We will be back in a couple of months !"

Reviewed on Jul 22, 2025

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The Dana on Mission Bay
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,780 reviews)
"I had a great experience at this hotel! Everything was spotlessly clean, and the service was excellent!friendly, helpful staff made me feel welcome from the moment I arrived. The location is also a big plus—within easy walking distance to lots of entertainment, restaurants, and attractions. I would ..."

Reviewed on Jul 22, 2025

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Marriott Marquis San Diego Marina
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8/10 Very Good! (1,307 reviews)
Great place to stay
"I was in San Diego for work. The hotel was outstanding. The restaurant was great quality and affordable made things very convenient. The pool area was beautiful and well maintained. The rooms were clean and the bed was comfortable."

Reviewed on Jul 22, 2025

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DoubleTree by Hilton San Diego - Del Mar
The Dextro Hotel, BW Premier Collection

The Dextro Hotel, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
7.6/10 Good! (1,037 reviews)
"Staff was very accommodating and acknowledged our separate requests. The pool is small but accessible until 11 PM. The gym is tucked away in a very discreet area, by the pool, which I appreciated. The property bar also had a happy hour, and the bar staff was just as nice and accommodating as the ..."

Reviewed on Jul 23, 2025

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The Dextro Hotel, BW Premier Collection
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4 out of 5
1 Park Blvd, San Diego, CA
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (1,609 reviews)
"From the moment we arrived we were welcomed. Our housekeeper was extremely helpful when we needed extra trash bags. We let her know the one we had was damaged. She fixed the problem right away. Room service was quick. I love that check out was done by text and it was quick and on point. Great ..."

Reviewed on Jul 23, 2025

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Hilton San Diego Bayfront
See all 8,107 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.