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Hotels in Mission

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Choose from 1576 Mission Hotel Deals

Hotel Lotus Kansas City Merriam

Hotel Lotus Kansas City Merriam

3 out of 5
9009 W Shawnee Mission Pkwy, Mission, KS
  • 16 min walk from KU Medical Center
Stay at this 3-star business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.6/10 Excellent! (1,630 reviews)
"I like that they provided an assortment of breakfast to choose from. Staff was friendly"

Reviewed on Jul 18, 2025

Hotel Lotus Kansas City Merriam
Econolodge Inn & Suites

Econolodge Inn & Suites

2 out of 5
7508 Shawnee Mission Pkwy, I-35 East / Shawnee Mission Parkway, Mission, KS
  • 13 min walk from KU Medical Center
Book a stay at this business-friendly motel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (999 reviews)
"N/A"

Reviewed on Jul 14, 2025

Econolodge Inn & Suites
Quality Inn Merriam Kansas City

Quality Inn Merriam Kansas City

2.5 out of 5
6401 E. Frontage Road, Merriam, Mission, KS
  • 18 min walk from KU Medical Center
Book a stay at this business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,003 reviews)
"."

Reviewed on Jul 3, 2025

Quality Inn Merriam Kansas City
Loews Kansas City Hotel

Loews Kansas City Hotel

4 out of 5
1515 Wyandotte Street, Kansas City, MO
  • 12 min drive from KU Medical Center
Stay at this 4-star business-friendly hotel in Kansas City. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the ...
9.6/10 Exceptional! (1,728 reviews)
"Thank you for the stay. It was one to remember!"

Reviewed on Jul 18, 2025

Loews Kansas City Hotel
Orangewood Inn & Suites Kansas City Airport

Orangewood Inn & Suites Kansas City Airport

3.5 out of 5
11828 NW Plaza Circle, Kansas City, MO
  • 48 min drive from KU Medical Center
Stay at this 3.5-star hotel in Kansas City. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (2,513 reviews)
"Property was satisfactory and close to airport"

Reviewed on Jul 17, 2025

Orangewood Inn & Suites Kansas City Airport
American Inn North Kansas City

American Inn North Kansas City

3.5 out of 5
1211 Armour Rd, North Kansas City, MO
  • 20 min drive from KU Medical Center
Stay at this 3.5-star business-friendly motel in North Kansas City. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and ...
6.8/10 (1,000 reviews)
"Not bad for a budget hotel"

Reviewed on Jul 13, 2025

American Inn North Kansas City
Embassy Suites by Hilton Kansas City Plaza

Embassy Suites by Hilton Kansas City Plaza

3.5 out of 5
220 W 43rd St, Kansas City, MO
  • 5 min drive from KU Medical Center
Book a stay at this business-friendly hotel in Kansas City. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the ...
6.6/10 (1,007 reviews)
"Ok"

Reviewed on Jul 16, 2025

Embassy Suites by Hilton Kansas City Plaza
Kansas City Marriott Downtown

Kansas City Marriott Downtown

4 out of 5
200 W 12th Street, Kansas City, MO
  • 13 min drive from KU Medical Center
Stay at this 4-star business-friendly hotel in Kansas City. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,012 reviews)
"Perfect for our one night stay"

Reviewed on Jul 19, 2025

Kansas City Marriott Downtown
Radisson Hotel Lenexa Overland Park

Radisson Hotel Lenexa Overland Park

3.5 out of 5
12601 West 95th Street, Lenexa, KS
  • 12 min drive from KU Medical Center
Stay at this 3.5-star business-friendly hotel in Lenexa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the clean rooms in our reviews. ...
6.6/10 (1,496 reviews)
"The breakfast was the best I’ve ever had. Phenomenal. Clean presentation of the hotel."

Reviewed on Jul 19, 2025

Radisson Hotel Lenexa Overland Park
InterContinental Kansas City at The Plaza by IHG

InterContinental Kansas City at The Plaza by IHG

4 out of 5
401 Ward Pkwy, Kansas City, MO
  • 4 min drive from KU Medical Center
Stay at this 4-star business-friendly hotel in Kansas City. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
8/10 Very Good! (1,005 reviews)
"Mine hotel in a good location. It is getting a little older but certainly still a good place to stay. Love the balcony and view."

Reviewed on Jul 19, 2025

InterContinental Kansas City at The Plaza by IHG
Argosy Casino & Hotel

Argosy Casino & Hotel

4 out of 5
777 N.W. Argosy Parkway, Riverside, MO
  • 23 min drive from KU Medical Center
Stay at this 4-star business-friendly hotel in Riverside. Enjoy free parking, 6 restaurants, and a casino. Our guests praise the clean rooms and the property ...
8/10 Very Good! (1,016 reviews)
Pleasant Stay
"It was a pleasant stay."

Reviewed on Jul 17, 2025

Argosy Casino & Hotel
Stoney Creek Hotel Kansas City - Independence

Stoney Creek Hotel Kansas City - Independence

3.5 out of 5
18011 Bass Pro Drive, Independence, MO
  • 12 min drive from KU Medical Center
Stay at this 3.5-star business-friendly hotel in Independence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,257 reviews)
"The area and hotel itself was great. I had an ant crawl on me but I did go outside. There was 6 of us and the room we had fit all of us. We liked the views and walking areas."

Reviewed on Jul 18, 2025

Stoney Creek Hotel Kansas City - Independence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mission

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $80. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mission hotel deals at the last minute.

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Frequently Asked Questions About Mission hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Mission?

With over 1,576 hotels in Mission, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $80.

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Finding a cheap car rental deal in Mission is as easy as scoring cheap hotels in Mission. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.