Search for Cheap Deals on
Hotels in Mission

Photo by Bethany Mayahi

Choose from 1615 Mission Hotel Deals

Hotel Lotus Kansas City Merriam
Hotel Lotus Kansas City Merriam
3 out of 5
9009 W Shawnee Mission Pkwy, Mission, KS
  • 16 min walk from KU Medical Center
Stay at this 3-star business-friendly hotel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.6/10 Excellent! (1,625 reviews)
Would stay here again.
"This was a good location for a fair price."

Reviewed on Jun 27, 2025

Hotel Lotus Kansas City Merriam
Econolodge Inn & Suites
Econolodge Inn & Suites
2 out of 5
7508 Shawnee Mission Pkwy, I-35 East / Shawnee Mission Parkway, Mission, KS
  • 13 min walk from KU Medical Center
Book a stay at this business-friendly motel in Mission. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,004 reviews)
"There were only 2 bath towels for 2 adults. Usually there are 3, at least. We stopped at the front desk and asked for 2 towels, we were told we could have one because a gentleman came and got 6 for the pool...There wasn't any conditioner, I bring my own but there should be conditioner/shampoo available ..."

Reviewed on Jun 23, 2025

Econolodge Inn & Suites
Orangewood Inn & Suites Kansas City Airport
Orangewood Inn & Suites Kansas City Airport
3.5 out of 5
11828 NW Plaza Circle, Kansas City, MO
  • 48 min drive from KU Medical Center
Stay at this 3.5-star hotel in Kansas City. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (2,413 reviews)
"Was a great place to stay"

Reviewed on Jun 28, 2025

Orangewood Inn & Suites Kansas City Airport
Loews Kansas City Hotel
Loews Kansas City Hotel
4 out of 5
1515 Wyandotte Street, Kansas City, MO
  • 12 min drive from KU Medical Center
Stay at this 4-star business-friendly hotel in Kansas City. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the ...
9.6/10 Exceptional! (1,695 reviews)
"Amazing property and service."

Reviewed on Jun 26, 2025

Loews Kansas City Hotel
Argosy Casino & Hotel
Argosy Casino & Hotel
4 out of 5
777 N.W. Argosy Parkway, Riverside, MO
  • 23 min drive from KU Medical Center
Stay at this 4-star business-friendly hotel in Riverside. Enjoy free parking, 6 restaurants, and a casino. Our guests praise the clean rooms and the property ...
8/10 Very Good! (1,011 reviews)
"Absolutely loved our stay here! The property was beautiful and quiet, I love that the rooms are far enough away from the Casino that you can rest peacefully. The beds are comfortable and there’s several options for food and drinks. They have an outdoor area to lounge and watch tv! Also a park really ..."

Reviewed on Jun 29, 2025

Argosy Casino & Hotel
American Inn North Kansas City
American Inn North Kansas City
3.5 out of 5
1211 Armour Rd, North Kansas City, MO
  • 20 min drive from KU Medical Center
Stay at this 3.5-star business-friendly motel in North Kansas City. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and ...
6.6/10 (1,016 reviews)
"Excellent"

Reviewed on Jun 24, 2025

American Inn North Kansas City
Wingate by Wyndham Kansas City
Wingate by Wyndham Kansas City
2.5 out of 5
7333 Parvin Road, Kansas City, MO
  • 25 min drive from KU Medical Center
Book a stay at this business-friendly hotel in Kansas City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
5.6/10 (1,012 reviews)
"The Hotel has a unique layout, the staff was pleasant, the hotel is outdated but clean"

Reviewed on Jun 29, 2025

Wingate by Wyndham Kansas City
Radisson Hotel Lenexa Overland Park
Radisson Hotel Lenexa Overland Park
3.5 out of 5
12601 West 95th Street, Lenexa, KS
  • 12 min drive from KU Medical Center
Stay at this 3.5-star business-friendly hotel in Lenexa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the clean rooms in our reviews. ...
6.6/10 (1,463 reviews)
"Got the room with Jaccuzi was beyond nice. Everything was good but AC stopped working. If it would have then be best trip ever"

Reviewed on Jun 28, 2025

Radisson Hotel Lenexa Overland Park
Hilton Kansas City Country Club Plaza
Hilton Kansas City Country Club Plaza
4.5 out of 5
770 W 47th St, Kansas City, MO
  • 4 min drive from KU Medical Center
Stay at this 4.5-star luxury hotel in Kansas City. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the ...
8.6/10 Excellent! (1,043 reviews)
"Near shopping nice room and pool"

Reviewed on Jun 26, 2025

Hilton Kansas City Country Club Plaza
Embassy Suites by Hilton Kansas City Plaza
Embassy Suites by Hilton Kansas City Plaza
3.5 out of 5
220 W 43rd St, Kansas City, MO
  • 5 min drive from KU Medical Center
Book a stay at this business-friendly hotel in Kansas City. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the ...
6.6/10 (1,002 reviews)
"Love the Embassy Suits, The two room layout is very comfortable. The breakfast is the best in the business, full buffet and cook to order eggs, pancakes and omits. I never make happy hour but they even give you free drinks and snacks. This is a great hotel."

Reviewed on Jun 22, 2025

Embassy Suites by Hilton Kansas City Plaza
Stoney Creek Hotel Kansas City - Independence
Stoney Creek Hotel Kansas City - Independence
3.5 out of 5
18011 Bass Pro Drive, Independence, MO
  • 12 min drive from KU Medical Center
Stay at this 3.5-star business-friendly hotel in Independence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,219 reviews)
"Friendly, clean, and great location"

Reviewed on Jun 29, 2025

Stoney Creek Hotel Kansas City - Independence
AC Hotel Kansas City Plaza
AC Hotel Kansas City Plaza
3.5 out of 5
560 Westport Rd, Kansas City, MO
  • 6 min drive from KU Medical Center
Stay at this 3.5-star business-friendly hotel in Kansas City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,004 reviews)
"The room was on the small side and could use some renovation. Overall it was a pleasant stay and the property was in a good location."

Reviewed on Jun 26, 2025

AC Hotel Kansas City Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mission

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mission hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mission.

Choosing the right hotel in Kansas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mission’s 1,615 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as . In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mission hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mission. No matter your reason for visiting Mission, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mission hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mission for as low as .

How many hotels are there in Mission?

With over 1,615 hotels in Mission, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as .

How to find cheap car rentals in Mission?

Finding a cheap car rental deal in Mission is as easy as scoring cheap hotels in Mission. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.