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Comfort Inn & Suites Orlando Sanford Airport

Comfort Inn & Suites Orlando Sanford Airport

4 out of 5
3043 East Lake Mary Boulevard Sanford FL
  • 17 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Seminole County Sports Complex ...
9.8/10 Exceptional! (292 reviews)
"Free 24 hour shuttle. Called when we landed picked us right up. 5 minute shuttle ride. Very clean, new property. Would stay again!"

Reviewed on Nov 15, 2026

Comfort Inn & Suites Orlando Sanford Airport
Holiday Inn Express & Suites Sanford- Lake Mary by IHG

Holiday Inn Express & Suites Sanford- Lake Mary by IHG

4 out of 5
4750 W State Road 46 Sanford FL
  • 4 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express & Suites Sanford- Lake Mary by IHG
Comfort Inn & Suites Orlando North

Comfort Inn & Suites Orlando North

2.5 out of 5
590 Ava Ct Sanford FL
  • 28 min walk from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Comfort Inn & Suites Orlando North
Best Western Plus Sanford Airport/Lake Mary Hotel

Best Western Plus Sanford Airport/Lake Mary Hotel

2.5 out of 5
3401 S Orlando Dr Sanford FL
  • 11 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.6/10 Good! (1,624 reviews)
"Room was clean and well maintained. Only problem was no barrier on shower and water came out on floor."

Reviewed on Nov 13, 2026

Best Western Plus Sanford Airport/Lake Mary Hotel
Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL

3 out of 5
5440 Forbes Pl Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Country Inn & Suites by Radisson, Orlando Airport, FL
Spark by Hilton Orlando near Universal

Spark by Hilton Orlando near Universal

2.5 out of 5
5635 Windhover Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,909 reviews)
"Very convenient to Universal and staff friendly"

Reviewed on Nov 14, 2026

Spark by Hilton Orlando near Universal
Renaissance Orlando Airport Hotel by Marriott

Renaissance Orlando Airport Hotel by Marriott

4 out of 5
5445 Forbes Pl Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
Renaissance Orlando Airport Hotel by Marriott
Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport

3 out of 5
5750 Hazeltine National Drive Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (4,375 reviews)
"Great"

Reviewed on Nov 14, 2026

Wingate by Wyndham - Orlando International Airport
Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport

3 out of 5
7500 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Ramada by Wyndham Suites Orlando Airport
Sheraton Suites Orlando Airport

Sheraton Suites Orlando Airport

3.5 out of 5
7550 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
8.8/10 Excellent! (2,110 reviews)
"Clean"

Reviewed on Nov 14, 2026

Sheraton Suites Orlando Airport
La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport

3 out of 5
7160 N Frontage Rd Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and ...
7.6/10 Good! (3,008 reviews)
"Dirty"

Reviewed on Nov 14, 2026

La Quinta Inn & Suites by Wyndham Orlando Airport
Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport

2.5 out of 5
5767 T.G. Lee Blvd. Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,203 reviews)
"Great location. Clean, EXCELLENT staff very kind and helpful"

Reviewed on Nov 15, 2026

Hampton Inn Orlando-International Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Sanford

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Sanford.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Sanford’s 2,548 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $57. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Sanford hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Sanford. No matter your reason for visiting Sanford, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Sanford hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Sanford for as low as $57.

How many hotels are there in Sanford?

With over 2,548 hotels in Sanford, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $57.

How to find cheap car rentals in Sanford?

Finding a cheap car rental deal in Sanford is as easy as scoring cheap hotels in Sanford. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.