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Hotels in Sanford

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Comfort Inn & Suites Orlando Sanford Airport

Comfort Inn & Suites Orlando Sanford Airport

4 out of 5
3043 East Lake Mary Boulevard Sanford FL
  • 17 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Seminole County Sports Complex ...
9.8/10 Exceptional! (271 reviews)
"5 ⭐️"

Reviewed on Nov 4, 2026

Comfort Inn & Suites Orlando Sanford Airport
Holiday Inn Express & Suites Sanford- Lake Mary by IHG

Holiday Inn Express & Suites Sanford- Lake Mary by IHG

4 out of 5
4750 W State Road 46 Sanford FL
  • 4 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,265 reviews)
"Awesome room great breakfast excellent service"

Reviewed on Nov 3, 2026

Holiday Inn Express & Suites Sanford- Lake Mary by IHG
Comfort Inn & Suites Orlando North

Comfort Inn & Suites Orlando North

2.5 out of 5
590 Ava Ct Sanford FL
  • 28 min walk from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,357 reviews)
"booked a suite 1 bedroom 550 sf. we got std Q room, no sofa sleeps 4. clerk at desk said all rooms are same size. paid extra for just a standard room. not happy with Hotel . com site."

Reviewed on Nov 2, 2026

Comfort Inn & Suites Orlando North
Best Western Plus Sanford Airport/Lake Mary Hotel

Best Western Plus Sanford Airport/Lake Mary Hotel

2.5 out of 5
3401 S Orlando Dr Sanford FL
  • 11 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Best Western Plus Sanford Airport/Lake Mary Hotel
Spark by Hilton Orlando near Universal

Spark by Hilton Orlando near Universal

2.5 out of 5
5635 Windhover Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,870 reviews)
"Love it"

Reviewed on Nov 4, 2026

Spark by Hilton Orlando near Universal
Renaissance Orlando Airport Hotel by Marriott

Renaissance Orlando Airport Hotel by Marriott

4 out of 5
5445 Forbes Pl Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
Renaissance Orlando Airport Hotel by Marriott
Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport

3 out of 5
5750 Hazeltine National Drive Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (4,352 reviews)
"Nice big room with a comfortable bed and hot shower."

Reviewed on Nov 3, 2026

Wingate by Wyndham - Orlando International Airport
Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL

3 out of 5
5440 Forbes Pl Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Country Inn & Suites by Radisson, Orlando Airport, FL
Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport

3 out of 5
7500 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Ramada by Wyndham Suites Orlando Airport
Sheraton Suites Orlando Airport

Sheraton Suites Orlando Airport

3.5 out of 5
7550 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
Sheraton Suites Orlando Airport
La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport

3 out of 5
7160 N Frontage Rd Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and ...
7.6/10 Good! (2,931 reviews)
"I chose this hotel for the free airport shuttle, however, apron arrival it was an automated system that I couldn’t get to work. After fighting with the automated phone system the person at the desk was less than helpful. We ended up taking a cab. One elevator out of service both stays & the second ..."

Reviewed on Nov 4, 2026

La Quinta Inn & Suites by Wyndham Orlando Airport
Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport

2.5 out of 5
5767 T.G. Lee Blvd. Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,202 reviews)
"Staff was extremely helpful with a problem we had that had nothing to do with the hotel! Thanks Mike!"

Reviewed on Nov 2, 2026

Hampton Inn Orlando-International Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Sanford

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Sanford.

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $55. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Sanford hotel deals at the last minute.

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Frequently Asked Questions About Sanford hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Sanford?

With over 2,572 hotels in Sanford, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $55.

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Finding a cheap car rental deal in Sanford is as easy as scoring cheap hotels in Sanford. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.