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Holiday Inn Express & Suites Sanford- Lake Mary by IHG

Holiday Inn Express & Suites Sanford- Lake Mary by IHG

4 out of 5
4750 W State Road 46 Sanford FL
  • 4 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,165 reviews)
"Clean and comfortable"

Reviewed on Jun 17, 2026

Holiday Inn Express & Suites Sanford- Lake Mary by IHG
Best Western Plus Sanford Airport/Lake Mary Hotel

Best Western Plus Sanford Airport/Lake Mary Hotel

2.5 out of 5
3401 S Orlando Dr Sanford FL
  • 11 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.4/10 Good! (1,591 reviews)
"The staff were SO accommodating! We were tired, wet, hungry with young children and the staff were simply lovely!"

Reviewed on Jun 16, 2026

Best Western Plus Sanford Airport/Lake Mary Hotel
Comfort Inn & Suites Orlando North

Comfort Inn & Suites Orlando North

2.5 out of 5
590 Ava Ct Sanford FL
  • 28 min walk from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,304 reviews)
"VERY GOOD FOR THE MONEY. Rooms clean but small. Good breakfast and good parking. Had to great things I love. A frig and microwave!!!"

Reviewed on Jun 16, 2026

Comfort Inn & Suites Orlando North
Sheraton Orlando North Hotel

Sheraton Orlando North Hotel

3.5 out of 5
600 N Lake Destiny Dr Maitland FL
  • 34 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Maitland. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,172 reviews)
"Excellent visit, staff was polite, accommodating everyone was clean. I will definitely stay again."

Reviewed on Jun 18, 2026

Sheraton Orlando North Hotel
La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport

3 out of 5
7160 N Frontage Rd Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and ...
7.4/10 Good! (2,165 reviews)
"I had a great stay at this hotel. The staff was friendly and helpful, the room was clean and comfortable, and the location was convenient. Everything exceeded my expectations. I would definitely stay here again and highly recommend it!"

Reviewed on Jun 18, 2026

La Quinta Inn & Suites by Wyndham Orlando Airport
Spark by Hilton Orlando near Universal

Spark by Hilton Orlando near Universal

2.5 out of 5
5635 Windhover Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,328 reviews)
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Reviewed on Jun 18, 2026

Spark by Hilton Orlando near Universal
Lakeside Inn

Lakeside Inn

3 out of 5
100 N Alexander St Mount Dora FL
  • 48 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this beach hotel in Mount Dora. Enjoy free parking, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,242 reviews)
"The hotel is in the most amazing location and the view from the dock is incredible. The bed wasn’t very comfy and the bathroom is very tiny but we understood it was a historical property."

Reviewed on Jun 18, 2026

Lakeside Inn
Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL

3 out of 5
5440 Forbes Pl Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
7.8/10 Good! (4,696 reviews)
"The room and Linden‘s were clean. The bathroom was very nice. I only wish I had been told when breakfast ended"

Reviewed on Jun 18, 2026

Country Inn & Suites by Radisson, Orlando Airport, FL
Sheraton Suites Orlando Airport

Sheraton Suites Orlando Airport

3.5 out of 5
7550 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
8.6/10 Excellent! (2,125 reviews)
"Very comfortable accommodation"

Reviewed on Jun 18, 2026

Sheraton Suites Orlando Airport
Marriott Orlando Downtown

Marriott Orlando Downtown

3.5 out of 5
400 W Livingston St Orlando FL
  • 48 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,003 reviews)
"Dirty pillows"

Reviewed on Jun 18, 2026

Marriott Orlando Downtown
Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport

3 out of 5
7500 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (5,859 reviews)
"Todo estaba excelente"

Reviewed on Jun 18, 2026

Ramada by Wyndham Suites Orlando Airport
Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport

3 out of 5
5750 Hazeltine National Drive Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (4,045 reviews)
"Very good hotel and personnel."

Reviewed on Jun 18, 2026

Wingate by Wyndham - Orlando International Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Sanford

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $80. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Sanford hotel deals at the last minute.

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Frequently Asked Questions About Sanford hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Sanford?

With over 2,386 hotels in Sanford, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $80.

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