Hotels Near
Santa Clara

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Featured Santa Clara Hotels

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (3,643 reviews)
"Everyrhing"

Reviewed on Feb 17, 2025

Hotel Riu Plaza Panama
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (1,866 reviews)
"While the staff was very attentive and nice, the receptionists were not diligent in preparing the correct receipt for the rooms i booked.lots of errors, but in all my family and I had a lovely stay, and would definitely recommend this hotel."

Reviewed on Feb 15, 2025

Plaza Paitilla Inn Hotel
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.2/10 Good! (1,001 reviews)
"My Cousin recommended me that Hotel and I did like it. Why? Because everything was included: Breakfast, Lunch, Dinner and Drinks. My family and I love it. We are planning to go back and take the tours all over the place."

Reviewed on Feb 13, 2025

Dreams Playa Bonita Panama - All Inclusive
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,057 reviews)
"Room getting renovated and they gave us free upgrade to there partner hotel, Megapolis."

Reviewed on Feb 16, 2025

Decapolis Hotel Panama City
Crowne Plaza Panama Airport, an IHG Hotel
Crowne Plaza Panama Airport, an IHG Hotel
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
8.2/10 Very Good! (2,074 reviews)
"The staff was friendly and very cordial"

Reviewed on Feb 13, 2025

Crowne Plaza Panama Airport, an IHG Hotel
The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8/10 Very Good! (1,002 reviews)
"the main thing that I like about this resort is that is a private area and the beach is exclusive to the Hotel, it gives you a much more safe and quiet enviroment. quality of the room are and service is great. My only down is that the coffee maker in the room is a joke. other than that it's all ..."

Reviewed on Feb 13, 2025

The Westin Playa Bonita Panama
JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,005 reviews)
"G"

Reviewed on Feb 13, 2025

JW Marriott Panama
Waldorf Astoria Panama
Waldorf Astoria Panama
5 out of 5
47th St. & Uruguay Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
"Sorry to say but not quiet with multiple families with small children and no restraint."

Reviewed on Feb 10, 2025

Waldorf Astoria Panama
W Panama
W Panama
5 out of 5
Calle Aquilino de la Guardia & Calle 50, Bella Vista, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy 2 restaurants, 3 spa tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,006 reviews)
"We loved everything"

Reviewed on Feb 15, 2025

W Panama
Marriott Panama Hotel
Marriott Panama Hotel
4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
"I loved the location."

Reviewed on Feb 7, 2025

Marriott Panama Hotel
AC Hotel by Marriott Panama City
AC Hotel by Marriott Panama City
3.5 out of 5
Calle Ricardo Arias 14, Campo Alegre Area Bancaria, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (563 reviews)
"Beatifull"

Reviewed on Feb 14, 2025

AC Hotel by Marriott Panama City
Hilton Panama
Hilton Panama
5 out of 5
Balboa Ave. and Aquilino De La Guardia, Panama City
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (1,002 reviews)
"Huge room with great bathroom. Very nice. Needs updated technology plug ins."

Reviewed on Feb 12, 2025

Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Clara

Panama City is a city that has a lot going on, but you have your sights set on Santa Clara. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Clara has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Clara hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Panama City so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Clara underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santa Clara city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Clara cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santa Clara at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $90
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santa Clara hotel you want, book it, and never look back. Because your great escape is ahead of you.