Hotels Near
Seneca

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Featured Seneca Hotels

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
7.8/10 Good! (2,875 reviews)
Staff!

Reviewed on Feb 2, 2026

Buffalo Airport Hotel
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Buffalo. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (2,240 reviews)
Great front staff

Reviewed on Jan 30, 2026

Garden Place Hotel
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8/10 Very Good! (1,730 reviews)
Great Stay

Reviewed on Jan 30, 2026

Hyatt Regency Buffalo / Hotel and Conference Center
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

3 out of 5
6619 Transit Rd Buffalo NY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,416 reviews)
Very nice guy checked me in. Very clean room. Perfect for my needs.

Reviewed on Jan 27, 2026

La Quinta Inn by Wyndham Buffalo Airport
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Fully refundable
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,977 reviews)
Great price. Helpful in using their shuttle. Marty the shuttle driver was very helpful. Only negative was the c/o detector in the hallway near our room battery was dying and making a noise at 3:30am until I said something at front desk at 8am and they sent someone to fix it.

Reviewed on Jan 29, 2026

Sleep Inn & Suites Buffalo Airport
La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3 out of 5
145 Innkeepers Lane Buffalo NY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (2,013 reviews)
Courteous staffing , clean rooms ,

Reviewed on Jan 31, 2026

La Quinta Inn & Suites by Wyndham Buffalo Amherst
Homewood Suites by Hilton Buffalo/Amherst

Homewood Suites by Hilton Buffalo/Amherst

3 out of 5
1138 Millersport Hwy Buffalo NY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,001 reviews)
Nice room, welcoming staff, wonderful breakfast and coffee, warm pool room and hot tub, convenient location

Reviewed on Jan 3, 2026

Homewood Suites by Hilton Buffalo/Amherst
Tru by Hilton Williamsville Buffalo Airport

Tru by Hilton Williamsville Buffalo Airport

2.5 out of 5
48 Freeman Road Buffalo NY
Fully refundableReserve now, pay when you stay
Stay at this hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,000 reviews)
Great hotel. The room was clean and perfect for our needs

Reviewed on Jan 26, 2026

Tru by Hilton Williamsville Buffalo Airport
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3 out of 5
125 High St Buffalo NY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,754 reviews)
Very good and very convenient to what I want

Reviewed on Feb 2, 2026

Wyndham Garden Buffalo Downtown
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 out of 5
2761 Long Road Grand Island NY
Fully refundable
Book a stay at this business-friendly hotel in Grand Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,668 reviews)
Room was pretty clean and staff was very nice!

Reviewed on Feb 2, 2026

Holiday Inn Express Grand Island - Niagara Falls by IHG
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 out of 5
601 Main St Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,000 reviews)
The room was clean, the staff were AMAZING, especially Mario and Eddie on the front desk!!! I cannot say how incredible the overall experience was. Would highly recommend

Reviewed on Jan 27, 2026

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
Motel 6 Amherst, NY - Buffalo

Motel 6 Amherst, NY - Buffalo

2 out of 5
4400 Maple Rd Buffalo NY
Fully refundableReserve now, pay when you stay
Stay at this motel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions ...
6.4/10 (1,006 reviews)
Clean and roomy

Reviewed on Jan 22, 2026

Motel 6 Amherst, NY - Buffalo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Seneca

Buffalo is a city that has a lot going on, but you have your sights set on Seneca. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Seneca has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Seneca hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Buffalo so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Seneca underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Seneca city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Seneca cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Seneca at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $68
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Seneca hotel you want, book it, and never look back. Because your great escape is ahead of you.