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Featured Seneca Resorts & Hotels with Spas
Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street, Seneca, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Seneca
Seneca Neighborhoods
Cities near Seneca
- Highlands Hotels (28.85 mi)
- Brevard Hotels (39.8 mi)
- North Carolina Mountains Hotels (75.4 mi)
- Anderson Hotels (21.32 mi)
- Clemson Hotels (6.58 mi)
- Cashiers Hotels (30.58 mi)
- Blue Ridge Mountains Hotels (84.01 mi)
- Clayton Hotels (28.66 mi)
- Tiger Hotels (29.4 mi)
- Sapphire Hotels (29.23 mi)
- Lake Toxaway Hotels (30.86 mi)
- Salem Hotels (14.16 mi)
- Clarkesville Hotels (32.86 mi)
- Dillard Hotels (31.47 mi)
- Toccoa Hotels (22.8 mi)
- Easley Hotels (22.2 mi)
- Hartwell Hotels (23.01 mi)
- Lavonia Hotels (19.33 mi)
- Central Hotels (10.12 mi)
- Sunset Hotels (21.97 mi)
Car Rentals Near Seneca
- Car rentals in Highlands
- Car rentals in Brevard
- Car rentals in North Carolina Mountains
- Car rentals in Anderson
- Car rentals in Clemson
- Car rentals in Cashiers
- Car rentals in Blue Ridge Mountains
- Car rentals in Clayton
- Car rentals in Tiger
- Car rentals in Sapphire
- Car rentals in Lake Toxaway
- Car rentals in Salem
- Car rentals in Clarkesville
- Car rentals in Dillard
- Car rentals in Toccoa
- Car rentals in Easley
Top Spa Resort Destinations
- Annapolis Spa Hotels
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- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
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- Grand Canyon Spa Hotels
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- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
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Top Booked Hotels in Seneca
- Quality Inn Seneca Clemson Area US-123
- Hampton Inn & Suites Seneca-Clemson Area
- Tru by Hilton Seneca Clemson
- Days Inn by Wyndham Seneca / Clemson Area
- Best Western Seneca-Clemson
- Days Inn by Wyndham Anderson
- Best Western Plus Clemson Hotel & Conference Center
- Comfort Inn & Suites Clemson - University Area