Search for Cheap Deals onIndependent in Southeast Missouri
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured Southeast Missouri Independent

The Riverview

The Farmstead Hotel

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Century Casino & Hotel Caruthersville

Honeysuckle Inn - Mountain View

Dexter Inn

New Orleans Inn Portageville

Echo Bluff State Park

Town House Inn Cape Giradreau

Town House Inn

Madison Inn Lodge

Current River Inn
Independent hotels in Southeast Missouri
You’ve already taken the guesswork out of your next vacation. You know you want a Independent hotel in Southeast Missouri. What can you say? You like their style, they’re in a good part of Southeast Missouri, and they never let you down. New bar in town? You’re the first one to check it out. Spiciest item on the menu? You can take the heat. But even the best gamblers hedge their bets. No matter how crazy good your trip is, you want something familiar waiting for you at the end of the day.
All in a name
We all have favorites. There’s nothing wrong with knowing what you like. You like to stay at Independent near , Southeast Missouri to do the tourist thing (because sometimes it is fun) and then hit up the places that aren’t on the map. And no matter what fun you get into, you have Independent hotels with their comfy beds and thoughtful amenities waiting to tuck you in.
As you like it
Have a price you want to stick to, so you can paint the town red? Maybe, it’s all about the hotel features. Who couldn’t use a hot tub? Pick your pleasure by:
- Hotwire Hot Rate: Grab the Independent hotel in Southeast Missouri at an absolute steal. After you book it, we’ll tell you the hotel name. You might nab that 4-star hotel for a 2-star price.
- Price: How low can we go? Quite low in fact. Check out our prices per night, starting at $64.
- Amenities: Grab a cocktail at the lounge and maybe wander upstairs to the rooftop terrace—all the stuff that makes a great vacay.
You’ve already done the hard part—figuring out where you want to stay. Now it’s time to use the money you saved to let the real fun begin. Underground shows? Off-beat attractions? Rooftop escapes? The choice is yours. The only thing wonderfully predictable about this trip is the Independent room you’ll be staying in.
- Top Hotels by Star Rating
- More Hotel Types
- Popular Attractions
- Other Brands
- Popular Neighborhoods
- Nearby Cities
Hotels by Star Rating
More Hotel Options in Southeast Missouri
- Hotels with Free Parking in Southeast Missouri
- Family Hotels in Southeast Missouri
- Pet-friendly Hotels in Southeast Missouri
- Hotels with a Pool in Southeast Missouri
- Hotels with an Indoor Pool in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotel Wedding Venues in Southeast Missouri
- Resorts & Hotels with Spas in Southeast Missouri
- Casinos in Southeast Missouri
- Luxury Hotels in Southeast Missouri
Top Points of Interests in Southeast Missouri
- Hotels near Johnson's Shut-ins State Park (33.71 mi)
- Hotels near Isle Casino Cape Girardeau (50.28 mi)
- Hotels near Southeast Missouri State University (49.58 mi)
- Hotels near Ozark National Scenic Riverways (45.96 mi)
- Hotels near Elephant Rocks State Park (33.16 mi)
- Hotels near Century Casino Caruthersville (83.29 mi)
- Hotels near Lake Wappapello (20.83 mi)
- Hotels near Alley Spring & Mill (56.14 mi)
- Hotels near Bonne Terre Mine (48.79 mi)
- Hotels near Taum Sauk Mountain State Park (29.09 mi)
- Hotels near Akers Ferry (62.71 mi)
- Hotels near Current River State Park (55.49 mi)
- Hotels near Echo Bluff State Park (54.11 mi)
- Hotels near National Shrine of Our Lady of the Miraculous Medal (45.55 mi)
- Hotels near Sainte Genevieve Winery (56.23 mi)
- Hotels near Hawn State Park (43.49 mi)
- Hotels near Rocky Falls (44.15 mi)
- Hotels near Riverfront Bridge Park (50.01 mi)
- Hotels near Big Spring (36.45 mi)
Other brands in Southeast Missouri
Top Neighborhoods in Southeast Missouri
- Chesterfield Hotels (99.53 mi)
- Cape Girardeau Hotels (50.24 mi)
- Carbondale Hotels (74.86 mi)
- Fenton Hotels (89.01 mi)
- Eureka Hotels (88.99 mi)
- Ozarks Hotels (113.87 mi)
- Arnold Hotels (83.54 mi)
- Kirkwood Hotels (93.89 mi)
- Sikeston Hotels (51.94 mi)
- Valley Park Hotels (91.6 mi)
- Poplar Bluff Hotels (32.28 mi)
- Richmond Heights Hotels (97.19 mi)
- Farmington Hotels (38.48 mi)
- Brentwood Hotels (96.34 mi)
- Festus Hotels (68.8 mi)
- Southern Illinois Hotels (119.89 mi)
- Wildwood Hotels (94.69 mi)
- Pacific Hotels (88.57 mi)
- West Plains Hotels (85.42 mi)
- Frontenac Hotels (97.5 mi)
