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Kid-Friendly Hotels in Southeast Missouri

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Featured Southeast Missouri Family Hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Pear Tree Inn Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Best Western Plus Sikeston
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Drury Inn & Suites Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
Comfort Suites Jackson-Cape Girardeau
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 out of 5
1802 Gamel Cemetery Road, Festus, MO
Fully refundable
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Drury Inn & Suites Jackson MO
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville
3 out of 5
1317 E Highway 84, Hayti, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Hayti. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites Hayti Caruthersville
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Dexter Inn
Dexter Inn
2.5 out of 5
1807 W Business US Highway 60, Dexter, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Dexter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions The ...
Dexter Inn
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Motel 6 Poplar Bluff, MO
Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Quality Inn Charleston - Sikeston
See all 561 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels with Pools in Southeast Missouri

Super 8 by Wyndham Pevely
Super 8 by Wyndham Pevely
2 out of 5
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (818 reviews)
Great port in a storm
"Arrived during tornado warning/ watch. Staff aware of danger. Very helpful"

Reviewed on Apr 6, 2025

Super 8 by Wyndham Pevely
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
Comfortable nice stay!
"Great experience! Nice clean hotel with many travelers on site. Safe and well lit parking lot."

Reviewed on Apr 22, 2025

Pear Tree Inn Sikeston
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature Collection
2.5 out of 5
4245 Hunt Rd, Farmington, MO
Book a stay at this golf hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (523 reviews)
"Nice staff"

Reviewed on Apr 13, 2025

Crown Pointe Lodge, BW Signature Collection
See all 561 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels With Connecting Rooms in Southeast Missouri

Comfort Inn Festus - St Louis South
Comfort Inn Festus - St Louis South
2.5 out of 5
1303 Veterans Blvd, Festus, MO
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Comfort Inn Festus - St Louis South
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature Collection
2.5 out of 5
4245 Hunt Rd, Farmington, MO
Book a stay at this golf hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Crown Pointe Lodge, BW Signature Collection
Days Inn by Wyndham Perryville
Days Inn by Wyndham Perryville
2 out of 5
1500 Liberty Street, Perryville, MO
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
Days Inn by Wyndham Perryville
See all 561 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.