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Luxury & Trendy Hotels in Southwest Houston

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Hotels in Southwest Houston

The St. Regis Houston
The St. Regis Houston
5 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from MD Anderson Cancer Center
The price is $455 per night from Jan 26 to Jan 27
$455
includes taxes & fees
Jan 26 - Jan 27
Stay at this 5-star luxury hotel in Houston. Enjoy a full-service spa, breakfast (surcharge), and 24-hour room service. Popular attractions NRG Stadium and Houston ...
The St. Regis Houston
Hotel Ylem
Hotel Ylem
3.5 out of 5
Fully refundableReserve now, pay when you stay
  • 20 min walk from MD Anderson Cancer Center
The price is $84 per night from Jan 16 to Jan 17
$84
includes taxes & fees
Jan 16 - Jan 17
Stay at this 3.5-star business-friendly aparthotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hotel Ylem
Hotel Granduca Houston
Hotel Granduca Houston
5 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from MD Anderson Cancer Center
The price is $432 per night from Jan 10 to Jan 11
$432
includes taxes & fees
Jan 10 - Jan 11
Stay at this 5-star luxury aparthotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the ...
Hotel Granduca Houston
Hotel Derek
Hotel Derek
4 out of 5
  • 6 min drive from MD Anderson Cancer Center
Stay at this aparthotel in Houston. Enjoy free WiFi, room service, and valet parking (surcharge). Our guests praise the clean rooms in our reviews. Popular attractions ...
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Hotel Derek
Hotel Vesper, Houston, a Tribute Portfolio Hotel
Hotel Vesper, Houston, a Tribute Portfolio Hotel
2.5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from MD Anderson Cancer Center
The price is $149 per night from Jan 19 to Jan 20
$149
includes taxes & fees
Jan 19 - Jan 20
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our ...
Hotel Vesper, Houston, a Tribute Portfolio Hotel
Aloft Houston by the Galleria
Aloft Houston by the Galleria
3 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $128 per night from Jan 12 to Jan 13
$128
includes taxes & fees
Jan 12 - Jan 13
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our ...
Aloft Houston by the Galleria
See all 1,350 properties in Southwest Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.