Search for Cheap Deals on
Hotels in Syosset

Choose from 2283 Syosset Hotel Deals

Ly New York Hotel

Ly New York Hotel

2.5 out of 5
15-61 127th St College Point NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in College Point. Enjoy free WiFi, a 24-hour front desk, and a 24-hour business center. Popular attractions Yankee ...
8.6/10 Excellent! (2,024 reviews)
Room was nice and modern but parking was a nightmare.

Reviewed on Feb 17, 2026

Ly New York Hotel
Sonesta White Plains Downtown

Sonesta White Plains Downtown

4 out of 5
66 Hale Ave White Plains NY
  • 56 min drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in White Plains. Enjoy free WiFi, breakfast (surcharge), and free airport pick-up. Our guests praise the bar and ...
8.6/10 Excellent! (1,305 reviews)
The pros: our room was lovely with a large bathroom and great lighting, with very comfortable beds and plenty of pillows. Everything was very clean, too. We needed a few things sent up during our stay [extra water bottles, a bandaid] and the staff was VERY helpful and quick- upon checking in the ...

Reviewed on Feb 18, 2026

Sonesta White Plains Downtown
DoubleTree by Hilton New York JFK Airport

DoubleTree by Hilton New York JFK Airport

3.5 out of 5
135-30 140th Street Jamaica NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in Jamaica. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8/10 Very Good! (1,385 reviews)
Smooth stay

Reviewed on Feb 20, 2026

DoubleTree by Hilton New York JFK Airport
Four Points by Sheraton Flushing

Four Points by Sheraton Flushing

3 out of 5
33-68 Farrington St Flushing NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Stay at this hotel in Flushing. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the pool and the restaurant in our reviews. ...
9/10 Wonderful! (2,893 reviews)
Everything good! Definitely will come back!

Reviewed on Feb 21, 2026

Four Points by Sheraton Flushing
The Parc Hotel

The Parc Hotel

2.5 out of 5
3916 College Point Blvd Flushing NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in Flushing. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,939 reviews)
good jus took to long with my deposit back 3-5 days

Reviewed on Feb 17, 2026

The Parc Hotel
voco Fiorello - LaGuardia Airport by IHG

voco Fiorello - LaGuardia Airport by IHG

4 out of 5
20-07 127th Street College Point NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in College Point. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.8/10 Excellent! (1,394 reviews)
Clean rooms & great staff

Reviewed on Feb 20, 2026

voco Fiorello - LaGuardia Airport by IHG
Hotel Mint JFK Airport

Hotel Mint JFK Airport

2.5 out of 5
10-74 Beach 22nd St Far Rockaway NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in Far Rockaway. Enjoy free WiFi, 24-hour room service, and a 24-hour front desk. Our guests praise the clean rooms ...
5.4/10 (1,717 reviews)
Everything was great. Only problem -no elictrical unit to boil water for tea.

Reviewed on Feb 19, 2026

Hotel Mint JFK Airport
Hotel Pergola JFK Airport

Hotel Pergola JFK Airport

2.5 out of 5
183-02 Jamaica ave Hollis NY
  • 57 min drive from Cold Spring Harbor Laboratory
Stay at this hotel in Hollis. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions UBS Arena and Resorts World Casino are located ...
6/10 (2,021 reviews)
Clean room

Reviewed on Feb 18, 2026

Hotel Pergola JFK Airport
Courtyard by Marriott New York JFK Airport

Courtyard by Marriott New York JFK Airport

3 out of 5
145-11 N Conduit Ave Jamaica NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in Jamaica. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,296 reviews)
Excellent stay, room clean, staff is very friendly and welcoming. Would recommend 10/10.

Reviewed on Feb 19, 2026

Courtyard by Marriott New York JFK Airport
Comfort Inn JFK Airport

Comfort Inn JFK Airport

2.5 out of 5
132-15 150th Avenue Jamaica NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in Jamaica. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and ...
8/10 Very Good! (5,058 reviews)
Great staff clean accomodating

Reviewed on Feb 18, 2026

Comfort Inn JFK Airport
Royal Regency Hotel

Royal Regency Hotel

3.5 out of 5
165 Tuckahoe Rd Yonkers NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Book a stay at this business-friendly hotel in Yonkers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.2/10 Very Good! (2,494 reviews)
Ideal location for our needs, complimentary breakfast, easy access to major roads.

Reviewed on Feb 18, 2026

Royal Regency Hotel
Hilton Garden Inn Queens/JFK Airport

Hilton Garden Inn Queens/JFK Airport

3 out of 5
14818 134th St Jamaica NY
  • 1 hour drive from Cold Spring Harbor Laboratory
Stay at this hotel in Jamaica. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (521 reviews)
The property itself is ok - there is a funky smell in the hallways and the room was a bit run down. But the staff was AMAZING! They all went above and beyond to make my last minute stay as easy as possible.

Reviewed on Feb 18, 2026

Hilton Garden Inn Queens/JFK Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Syosset

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Syosset hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Syosset.

Choosing the right hotel in New York has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Syosset’s 2,283 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $90. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Syosset hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Syosset. No matter your reason for visiting Syosset, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Syosset hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Syosset for as low as $90.

How many hotels are there in Syosset?

With over 2,283 hotels in Syosset, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $90.

How to find cheap car rentals in Syosset?

Finding a cheap car rental deal in Syosset is as easy as scoring cheap hotels in Syosset. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.