Search for Cheap Deals on
4 Star Hotels in East St. Louis

Photo by Janell Barger

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured 4 Star East St. Louis Hotels

Hyatt Regency St. Louis at The Arch
4 out of 5
Fully refundableReserve now, pay when you stay
  • 11 min walk from Casino Queen
The price is $117 per night from Dec 24 to Dec 25
$117
includes taxes & fees
Dec 24 - Dec 25
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 23 min walk from Casino Queen
The price is $161 per night from Dec 24 to Dec 25
$161
includes taxes & fees
Dec 24 - Dec 25
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 14 min walk from Casino Queen
The price is $104 per night from Dec 27 to Dec 28
$104
includes taxes & fees
Dec 27 - Dec 28
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Save an average of 15% on thousands of hotels when you're signed in
The Last Hotel
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 22 min walk from Casino Queen
The price is $135 per night from Jan 3 to Jan 4
$135
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Last Hotel
Live by Loews - St.Louis
4 out of 5
Fully refundableReserve now, pay when you stay
  • 16 min walk from Casino Queen
The price is $172 per night from Dec 24 to Dec 25
$172
includes taxes & fees
Dec 24 - Dec 25
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Live by Loews - St.Louis
St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 26 min walk from Casino Queen
The price is $191 per night from Jan 12 to Jan 13
$191
includes taxes & fees
Jan 12 - Jan 13, 2025
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
St. Louis Union Station Hotel, Curio Collection by Hilton
Hilton Pennywell St. Louis at the Arch
4 out of 5
Fully refundableReserve now, pay when you stay
  • 11 min walk from Casino Queen
The price is $117 per night from Jan 3 to Jan 4
$117
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the ...
Hilton Pennywell St. Louis at the Arch
DoubleTree by Hilton St. Louis Forest Park
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Casino Queen
The price is $165 per night from Dec 25 to Dec 26
$165
includes taxes & fees
Dec 25 - Dec 26
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
DoubleTree by Hilton St. Louis Forest Park
Embassy Suites by Hilton St. Louis Downtown
4 out of 5
Fully refundableReserve now, pay when you stay
  • 13 min walk from Casino Queen
The price is $129 per night from Dec 29 to Dec 30
$129
includes taxes & fees
Dec 29 - Dec 30
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and WiFi (surcharge). Our guests praise the breakfast and the ...
Embassy Suites by Hilton St. Louis Downtown
The Westin St. Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 17 min walk from Casino Queen
The price is $128 per night from Jan 10 to Jan 11
$128
includes taxes & fees
Jan 10 - Jan 11, 2025
Book a stay at this luxury hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and valet parking (surcharge). Our guests praise the helpful ...
The Westin St. Louis
 The Royal Sonesta Chase Park Plaza St. Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Casino Queen
The price is $251 per night from Dec 30 to Dec 31
$251
includes taxes & fees
Dec 30 - Dec 31
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
The Royal Sonesta Chase Park Plaza St. Louis
Marriott St. Louis Grand
4 out of 5
Fully refundableReserve now, pay when you stay
  • 14 min walk from Casino Queen
The price is $161 per night from Dec 30 to Dec 31
$161
includes taxes & fees
Dec 30 - Dec 31
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise ...
Marriott St. Louis Grand
Don't see what you're looking for?
See all available properties in East St. Louis
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in East St. Louis

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in East St. Louis for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in East St. Louis as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag East St. Louis 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in East St. Louis starting at $104 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded East St. Louis 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.