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4 Star Hotels in Mediterranean Region

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Featured 4 Star Mediterranean Region Hotels

Hotel Quirinale
4 out of 5
  • 31 hours drive from Duoro River
The price is $350 per night from Sep 29 to Sep 30
$350
includes taxes & fees
Sep 29 - Sep 30
Stay at this 4-star family-friendly hotel in Rome. Enjoy free WiFi, room service, and a fitness center. Our guests praise the breakfast and the bar in our reviews. ...
Hotel Quirinale
Barcelona Airport Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 17 hours drive from Duoro River
The price is $203 per night from Sep 30 to Oct 1
$203
includes taxes & fees
Sep 30 - Oct 1
Stay at this 4-star business-friendly hotel in El Prat de Llobregat. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Our guests praise the breakfast and ...
Barcelona Airport Hotel
Best Western Hotel Rome Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 34 hours drive from Duoro River
The price is $157 per night from Oct 20 to Oct 21
$157
includes taxes & fees
Oct 20 - Oct 21
Stay at this 4-star business-friendly hotel in Fiumicino. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Best Western Hotel Rome Airport
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Hilton Rome Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 33 hours drive from Duoro River
The price is $291 per night from Oct 11 to Oct 12
$291
includes taxes & fees
Oct 11 - Oct 12
Stay at this 4-star eco-certified hotel in Fiumicino. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the breakfast ...
Hilton Rome Airport
Hotel Emperador
4 out of 5
  • 4 hours drive from Duoro River
The price is $233 per night from Sep 29 to Sep 30
$233
includes taxes & fees
Sep 29 - Sep 30
Stay at this 4-star business-friendly hotel in Madrid. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
Hotel Emperador
Hilton Garden Inn Rome Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 33 hours drive from Duoro River
The price is $200 per night from Oct 23 to Oct 24
$200
includes taxes & fees
Oct 23 - Oct 24
Stay at this 4-star business-friendly hotel in Fiumicino. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast ...
Hilton Garden Inn Rome Airport
Hotel Riu Plaza España
4 out of 5
  • 4 hours drive from Duoro River
The price is $222 per night from Oct 6 to Oct 7
$222
includes taxes & fees
Oct 6 - Oct 7
Stay at this 4-star eco-certified hotel in Madrid. Enjoy free WiFi, an outdoor pool, and 2 bars/lounges. Our guests praise the breakfast and the pool in our ...
Hotel Riu Plaza España
INNSiDE by Melia Barcelona Apolo
4 out of 5
Fully refundableReserve now, pay when you stay
  • 17 hours drive from Duoro River
The price is $202 per night from Oct 14 to Oct 15
$202
includes taxes & fees
Oct 14 - Oct 15
Stay at this 4-star business-friendly hotel in Barcelona. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the ...
INNSiDE by Melia Barcelona Apolo
The Social Hub Florence Lavagnini
4 out of 5
Fully refundable
The price is $174 per night from Oct 27 to Oct 28
$174
includes taxes & fees
Oct 27 - Oct 28
Stay at this 4-star business-friendly hotel in Florence. Enjoy free WiFi, 2 bars/lounges, and a rooftop terrace. Our guests praise the breakfast and the pool ...
The Social Hub Florence Lavagnini
Ramada by Wyndham Lisbon
4 out of 5
Fully refundableReserve now, pay when you stay
  • 2 hours drive from Duoro River
The price is $161 per night from Oct 19 to Oct 20
$161
includes taxes & fees
Oct 19 - Oct 20
Stay at this 4-star business-friendly hotel in Lisbon. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
Ramada by Wyndham Lisbon
Senator Barajas
4 out of 5
  • 5 hours drive from Duoro River
The price is $122 per night from Oct 13 to Oct 14
$122
includes taxes & fees
Oct 13 - Oct 14
Book a stay at this business-friendly hotel in Madrid. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Senator Barajas
Expo Hotel Barcelona
4 out of 5
  • 17 hours drive from Duoro River
Stay at this 4-star business-friendly hotel in Barcelona. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Expo Hotel Barcelona
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Mediterranean Region

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Mediterranean Region for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Mediterranean Region as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Mediterranean Region 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Mediterranean Region starting at $122 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Mediterranean Region 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.