Search for Cheap Deals on
4 Star Hotels in Northeast Missouri

Check Last Minute Northeast Missouri Hotel Deals

Tonight Nov 23 - Nov 24Next weekend Nov 29 - Dec 1

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!


Featured 4 Star Northeast Missouri Hotels

Moonrise Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 10 min drive from St. Louis Union Station
The price is $151 per night from Nov 24 to Nov 25
$151
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Moonrise Hotel
The Last Hotel
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min walk from St. Louis Union Station
The price is $117 per night from Dec 12 to Dec 13
$117
includes taxes & fees
Dec 12 - Dec 13
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Last Hotel
21C Museum Hotel St Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min walk from St. Louis Union Station
The price is $133 per night from Dec 1 to Dec 2
$133
includes taxes & fees
Dec 1 - Dec 2
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
Save an average of 15% on thousands of hotels when you're signed in
The Cheshire
4 out of 5
Fully refundableReserve now, pay when you stay
  • 10 min drive from St. Louis Union Station
The price is $153 per night from Nov 25 to Nov 26
$153
includes taxes & fees
Nov 25 - Nov 26
Book a stay at this boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
The Cheshire
River City Casino & Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 min drive from St. Louis Union Station
The price is $137 per night from Nov 24 to Nov 25
$137
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
River City Casino & Hotel
Renaissance St. Louis Airport Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 21 min drive from St. Louis Union Station
The price is $135 per night from Dec 6 to Dec 7
$135
includes taxes & fees
Dec 6 - Dec 7
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Renaissance St. Louis Airport Hotel
Marriott St. Louis Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 24 min drive from St. Louis Union Station
The price is $153 per night from Nov 29 to Nov 30
$153
includes taxes & fees
Nov 29 - Nov 30
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
Marriott St. Louis Airport
Live by Loews - St.Louis
4 out of 5
Fully refundableReserve now, pay when you stay
  • 13 min walk from St. Louis Union Station
The price is $172 per night from Dec 23 to Dec 24
$172
includes taxes & fees
Dec 23 - Dec 24
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Live by Loews - St.Louis
 The Royal Sonesta Chase Park Plaza St. Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from St. Louis Union Station
The price is $251 per night from Dec 22 to Dec 23
$251
includes taxes & fees
Dec 22 - Dec 23
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
The Royal Sonesta Chase Park Plaza St. Louis
Embassy Suites by Hilton St. Louis Downtown
4 out of 5
Fully refundableReserve now, pay when you stay
  • 14 min walk from St. Louis Union Station
The price is $129 per night from Dec 1 to Dec 2
$129
includes taxes & fees
Dec 1 - Dec 2
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and WiFi (surcharge). Our guests praise the breakfast and the ...
Embassy Suites by Hilton St. Louis Downtown
Angad Arts Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 23 min walk from St. Louis Union Station
The price is $178 per night from Nov 24 to Nov 25
$178
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Angad Arts Hotel
Marriott St. Louis Grand
4 out of 5
Fully refundableReserve now, pay when you stay
  • 13 min walk from St. Louis Union Station
The price is $161 per night from Nov 29 to Nov 30
$161
includes taxes & fees
Nov 29 - Nov 30
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise ...
Marriott St. Louis Grand
Don't see what you're looking for?
See all available properties in Northeast Missouri
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Northeast Missouri

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Northeast Missouri for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Northeast Missouri as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Northeast Missouri 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Northeast Missouri starting at $117 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Northeast Missouri 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.