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5 Star Hotels in Gulf of Mexico

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Featured 5 Star Gulf of Mexico Hotels

The Roosevelt New Orleans, A Waldorf Astoria Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $260 per night from Apr 7 to Apr 8
$260
per night
Apr 7 - Apr 8
Stay at this 5-star luxury hotel in New Orleans. Enjoy 4 restaurants, 2 bars/lounges, and a full-service spa. Our guests praise the helpful staff and the clean ...
The Roosevelt New Orleans, A Waldorf Astoria Hotel
Hotel Effie Sandestin
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $227 per night from Apr 28 to Apr 29
$227
per night
Apr 28 - Apr 29
Stay at this 5-star luxury hotel in Miramar Beach. Enjoy free WiFi, a golf course, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Hotel Effie Sandestin
Four Seasons Hotel New Orleans
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $430 per night from Apr 22 to Apr 23
$430
per night
Apr 22 - Apr 23
Stay at this 5-star luxury hotel in New Orleans. Enjoy free WiFi, a full-service spa, and breakfast. Our guests praise the pool and the bar in our reviews. Popular ...
Four Seasons Hotel New Orleans
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The Windsor Court
5 out of 5
Stay at this spa hotel in New Orleans. Enjoy a full-service spa, breakfast, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
The Windsor Court
The Tampa EDITION
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $390 per night from Apr 14 to Apr 15
$390
per night
Apr 14 - Apr 15
Stay at this 5-star luxury hotel in Tampa. Enjoy free WiFi, 3 restaurants, and 4 bars/lounges. Popular attractions Port of Tampa and Seminole Hard Rock Casino ...
The Tampa EDITION
The Ritz-Carlton, New Orleans
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $319 per night from Apr 28 to Apr 29
$319
per night
Apr 28 - Apr 29
Stay at this 5-star luxury hotel in New Orleans. Enjoy a full-service spa, breakfast, and 24-hour room service. Our guests praise the helpful staff and the clean ...
The Ritz-Carlton, New Orleans
The Ritz-Carlton, Sarasota
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $699 per night from Apr 14 to Apr 15
$699
per night
Apr 14 - Apr 15
Stay at this 5-star luxury hotel in Sarasota. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Popular attractions St. Armands Circle and Lido Beach are ...
The Ritz-Carlton, Sarasota
The Henderson Beach Resort & Spa
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $349 per night from Mar 31 to Apr 1
$349
per night
Mar 31 - Apr 1
Stay at this 5-star luxury resort in Destin. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...
The Henderson Beach Resort & Spa
Casa Marina Key West, Curio Collection by Hilton
5 out of 5
Fully refundableReserve now, pay when you stay
The price is $575 per night from Apr 24 to Apr 25
$575
per night
Apr 24 - Apr 25
Stay at this 5-star luxury resort in Key West. Enjoy 2 outdoor pools, a private beach, and a full-service spa. Popular attractions Duval Street and Simonton ...
Casa Marina Key West, Curio Collection by Hilton
Bahama Breeze
5 out of 5
Stay at this 5-star luxury apartment in Panama City Beach. Enjoy free WiFi, free parking, and a picnic area. Popular attractions Pier Park and Panama City Beaches ...
Bahama Breeze
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5-Star Hotel in Gulf of Mexico

It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in Gulf of Mexico.

So nice you’ll blink twice

What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.

Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.

Stars in your eyes

Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in Gulf of Mexico for you. Sort by:

  • Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $227.

  • Amenities: Gulf of Mexico skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.

When you’re looking for the top 5-star hotels in Gulf of Mexico—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on Gulf of Mexico your way.