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5 Star Hotels in San Ysidro

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We pick the perfect hotel, packed with all your must-haves.

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Featured 5 Star San Ysidro Hotels

Pendry San Diego
5 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from San Ysidro Border Crossing
The price is $382 per night from Jan 12 to Jan 13
$382
includes taxes & fees
Jan 12 - Jan 13, 2025
Stay at this 5-star luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
Pendry San Diego
THE US GRANT, a Luxury Collection Hotel, San Diego
5 out of 5
Fully refundableReserve now, pay when you stay
  • 30 min drive from San Ysidro Border Crossing
The price is $314 per night from Dec 24 to Dec 25
$314
includes taxes & fees
Dec 24 - Dec 25
Stay at this 5-star luxury hotel in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful ...
THE US GRANT, a Luxury Collection Hotel, San Diego
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5-Star Hotel in San Ysidro

It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in San Ysidro.

So nice you’ll blink twice

What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.

Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.

Stars in your eyes

Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in San Ysidro for you. Sort by:

  • Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $314.

  • Amenities: San Ysidro skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.

When you’re looking for the top 5-star hotels in San Ysidro—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on San Ysidro your way.