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Featured Clayton Resorts & Hotels with Spas
The Ritz-Carlton, St. Louis
100 Carondelet Plaza, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
216 N Meramec Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Clayton
Clayton Neighborhoods
Top Points of Interests in Clayton
- Hotels near Chapel of St. Timothy And St. Titus
- Hotels near St. Louis Union Station
- Hotels near Enterprise Center
- Hotels near Gateway Arch
- Hotels near Busch Stadium
- Hotels near St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near Dome at America’s Center
- Hotels near Barnes Jewish Hospital
- Hotels near City Museum
- Hotels near Hollywood Casino Amphitheatre
- Hotels near St. Louis University
- Hotels near Mississippi River
- Hotels near Ameristar Casino St. Charles
- Hotels near America's Center Convention Complex
- Hotels near Fox Theater
- Hotels near Westport Plaza
- Hotels near Saint Louis Galleria Mall
- Hotels near St Charles Convention Center
Cities near Clayton
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Chesterfield Hotels (13.04 mi)
- O'Fallon Hotels (22.54 mi)
- Hazelwood Hotels (10.12 mi)
- St. Peters Hotels (19 mi)
- O'Fallon Hotels (23.35 mi)
- Fairview Heights Hotels (17.13 mi)
- Collinsville Hotels (18.31 mi)
- Edwardsville Hotels (21.4 mi)
- Fenton Hotels (11.04 mi)
- Ozarks Hotels (156.82 mi)
- Alton Hotels (18.7 mi)
- Belleville Hotels (20.19 mi)
- Arnold Hotels (14.77 mi)
- Brentwood Hotels (2.21 mi)
- Kirkwood Hotels (6.06 mi)
- Eureka Hotels (19.05 mi)
- Richmond Heights Hotels (0.98 mi)
- Wildwood Hotels (16.89 mi)
Car Rentals Near Clayton
- Car rentals in St. Charles
- Car rentals in Maryland Heights
- Car rentals in Chesterfield
- Car rentals in O'Fallon
- Car rentals in Hazelwood
- Car rentals in St. Peters
- Car rentals in O'Fallon
- Car rentals in Fairview Heights
- Car rentals in Collinsville
- Car rentals in Edwardsville
- Car rentals in Fenton
- Car rentals in Ozarks
- Car rentals in Alton
- Car rentals in Belleville
- Car rentals in Arnold
- Car rentals in Brentwood
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Clayton
- Clayton Plaza Hotel & Extended Stay
- Le Méridien St. Louis Clayton
- Homewood Suites by Hilton St Louis - Galleria
- Hampton Inn & Suites Clayton/St. Louis-Galleria Area
- Hollywood Casino & Hotel St. Louis
- Hyatt Regency St. Louis at The Arch
- The Last Hotel
- Renaissance St. Louis Airport Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)