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Featured 4 Star Clayton Hotels
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The price is $151 per night from Mar 28 to Mar 29
$151
includes taxes & fees
Mar 28 - Mar 29
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
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The price is $133 per night from Mar 17 to Mar 18
$133
includes taxes & fees
Mar 17 - Mar 18
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
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The price is $151 per night from Mar 19 to Mar 20
$151
includes taxes & fees
Mar 19 - Mar 20
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
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Fully refundableReserve now, pay when you stay
The price is $180 per night from Mar 17 to Mar 18
$180
includes taxes & fees
Mar 17 - Mar 18
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
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The price is $189 per night from Mar 16 to Mar 17
$189
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
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The price is $124 per night from Mar 17 to Mar 18
$124
includes taxes & fees
Mar 17 - Mar 18
Stay at this 4-star family-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
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The price is $135 per night from Mar 28 to Mar 29
$135
includes taxes & fees
Mar 28 - Mar 29
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
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The price is $214 per night from Mar 16 to Mar 17
$214
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
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The price is $227 per night from Mar 20 to Mar 21
$227
includes taxes & fees
Mar 20 - Mar 21
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
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The price is $187 per night from Mar 16 to Mar 17
$187
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
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The price is $182 per night from Mar 16 to Mar 17
$182
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
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The price is $158 per night from Mar 20 to Mar 21
$158
includes taxes & fees
Mar 20 - Mar 21
Book a stay at this luxury hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and valet parking (surcharge). Our guests praise the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Westport Plaza (7.79 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near Anheuser-Busch Brewery (6.88 mi)
- Hotels near St. Louis Aquarium at Union Station (6.35 mi)
Nearby Cities
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Chesterfield Hotels (13.04 mi)
- O'Fallon Hotels (22.54 mi)
- O'Fallon Hotels (23.35 mi)
- Hazelwood Hotels (10.12 mi)
- St. Peters Hotels (19 mi)
- Alton Hotels (18.7 mi)
- Fairview Heights Hotels (17.13 mi)
- Ozarks Hotels (156.82 mi)
- Collinsville Hotels (18.31 mi)
- Richmond Heights Hotels (0.98 mi)
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Car Rentals Near Clayton
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