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Featured 4 Star Clayton Hotels
Fully refundableReserve now, pay when you stay
The price is $117 per night from Dec 30 to Dec 31
$117
includes taxes & fees
Dec 30 - Dec 31
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Fully refundableReserve now, pay when you stay
The price is $133 per night from Jan 24 to Jan 25
$133
includes taxes & fees
Jan 24 - Jan 25, 2025
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Fully refundableReserve now, pay when you stay
The price is $170 per night from Dec 30 to Dec 31
$170
includes taxes & fees
Dec 30 - Dec 31
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
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Fully refundableReserve now, pay when you stay
The price is $189 per night from Dec 30 to Dec 31
$189
includes taxes & fees
Dec 30 - Dec 31
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
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The price is $214 per night from Jan 2 to Jan 3
$214
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
Fully refundableReserve now, pay when you stay
The price is $117 per night from Jan 20 to Jan 21
$117
includes taxes & fees
Jan 20 - Jan 21, 2025
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
Fully refundableReserve now, pay when you stay
The price is $135 per night from Jan 3 to Jan 4
$135
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
Fully refundableReserve now, pay when you stay
The price is $139 per night from Jan 2 to Jan 3
$139
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
Fully refundableReserve now, pay when you stay
The price is $189 per night from Jan 1 to Jan 2
$189
includes taxes & fees
Jan 1 - Jan 2, 2025
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Fully refundableReserve now, pay when you stay
The price is $187 per night from Jan 1 to Jan 2
$187
includes taxes & fees
Jan 1 - Jan 2, 2025
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Fully refundableReserve now, pay when you stay
The price is $171 per night from Jan 5 to Jan 6
$171
includes taxes & fees
Jan 5 - Jan 6, 2025
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
Fully refundableReserve now, pay when you stay
The price is $122 per night from Jan 5 to Jan 6
$122
includes taxes & fees
Jan 5 - Jan 6, 2025
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Popular Clayton Hotels
- Clayton Plaza Hotel & Extended Stay
- Le Méridien St. Louis Clayton
- The Ritz-Carlton, St. Louis
- Homewood Suites by Hilton St Louis - Galleria
- Hampton Inn & Suites Clayton/St. Louis-Galleria Area
- Hyatt Regency St. Louis at The Arch
- Hollywood Casino & Hotel St. Louis
- The Last Hotel
- Renaissance St. Louis Airport Hotel
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near St Charles Convention Center (12.99 mi)
- Hotels near Missouri Botanical Gardens and Arboretum (4.03 mi)
- Hotels near Horseshoe St. Louis Casino (7.55 mi)
Nearby Cities
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Chesterfield Hotels (13.04 mi)
- O'Fallon Hotels (22.54 mi)
- Hazelwood Hotels (10.12 mi)
- Bridgeton Hotels (9.81 mi)
- St. Peters Hotels (19 mi)
- O'Fallon Hotels (23.35 mi)
- St. Ann Hotels (7.04 mi)
- Collinsville Hotels (18.31 mi)
- Fairview Heights Hotels (17.13 mi)
- Fenton Hotels (11.04 mi)
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Car Rentals Near Clayton
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