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Featured 5 Star Clayton Hotels
Fully refundable
The price is $452 per night from Dec 23 to Dec 24
$452
includes taxes & fees
Dec 23 - Dec 24
Stay at this 5-star luxury hotel in St. Louis. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
Fully refundableReserve now, pay when you stay
The price is $605 per night from Dec 27 to Dec 28
$605
includes taxes & fees
Dec 27 - Dec 28
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Clayton
- Historic Hotels in Clayton
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- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Popular Clayton Hotels
- Clayton Plaza Hotel & Extended Stay
- Le Méridien St. Louis Clayton
- Homewood Suites by Hilton St Louis - Galleria
- Hampton Inn & Suites Clayton/St. Louis-Galleria Area
- Hollywood Casino & Hotel St. Louis
- Hyatt Regency St. Louis at The Arch
- The Last Hotel
- Renaissance St. Louis Airport Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near Westport Plaza (7.79 mi)
- Hotels near Saint Louis Galleria Mall (1.39 mi)
- Hotels near St Charles Convention Center (12.99 mi)
Nearby Cities
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Chesterfield Hotels (13.04 mi)
- O'Fallon Hotels (22.54 mi)
- Hazelwood Hotels (10.12 mi)
- St. Peters Hotels (19 mi)
- O'Fallon Hotels (23.35 mi)
- Fairview Heights Hotels (17.13 mi)
- Collinsville Hotels (18.31 mi)
- Edwardsville Hotels (21.4 mi)
- Fenton Hotels (11.04 mi)
- Ozarks Hotels (156.82 mi)
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Car Rentals Near Clayton
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