Search Cheap Flights to
Santiago Metropolitan Region from $361

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap round-trip flights to Santiago Metropolitan Region

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

SKY AIRLINE
Arajet
Copa
United
Delta
avianca
American Airlines
LATAM Airlines Group
LATAM Airlines Group
Delta
LATAM Airlines Group
American Airlines
Air Canada
American Airlines
Aeromexico
Copa

Flights to Santiago Metropolitan Region starting at $361

Have you been telling yourself, “2026 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to Santiago Metropolitan Region is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in Santiago Metropolitan Region that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to Santiago Metropolitan Region? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to Santiago Metropolitan Region by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to Santiago Metropolitan Region. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from $361 to $1,482.
  • Duration: Want to get to Santiago Metropolitan Region as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to Santiago Metropolitan Region today and get going.

Last Minute Hotel Deals in Santiago Metropolitan Region

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG

4 out of 5
Armando Cortinez Norte 2150 Santiago Region Metropolitana
Book a stay at this ski hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in ...
9/10 Wonderful! (1,436 reviews)
Amenities were fabulous

Reviewed on Feb 25, 2026

Opens in a new windowHoliday Inn Santiago - Airport Terminal by IHG
Hotel Capital Bellet

Hotel Capital Bellet

3 out of 5
Saint Paul 1457 / Antonio Bellet 135 Santiago Providencia
Book a stay at this business-friendly hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (987 reviews)
Great location 👌

Reviewed on Mar 2, 2026

Opens in a new windowHotel Capital Bellet
DoubleTree by Hilton Hotel Santiago - Vitacura

DoubleTree by Hilton Hotel Santiago - Vitacura

4 out of 5
Avenida Vitacura 2727, Las Condes Santiago
Stay at this hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.4/10 Exceptional! (1,002 reviews)
Yes clean Rooms and courteous staff.

Reviewed on Feb 25, 2026

Opens in a new windowDoubleTree by Hilton Hotel Santiago - Vitacura
Save an average of 15% on thousands of hotels when you're signed in
ICON Hotel

ICON Hotel

4 out of 5
Av. Alonso de Cordova 6050 Santiago
Book a stay at this spa hotel in Santiago. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,004 reviews)
Great room, nice staff, nice property, convenient parking, nice restaurant and breakfast

Reviewed on Feb 24, 2026

Opens in a new windowICON Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.