Hotels Near
Mission Bay

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Featured Mission Bay Hotels

The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular ...
8.8/10 Excellent! (3,814 reviews)
Comfortable beds and good sized rooms. Property is outdat

Reviewed on Oct 27, 2025

The Dana on Mission Bay
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,557 reviews)
The staff was personable and professional. I love the balcony view of the marina and we were in walking distance to Starbucks. :)

Reviewed on Oct 24, 2025

Hyatt Regency Mission Bay Spa and Marina
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,307 reviews)
Wonderful!

Reviewed on Oct 28, 2025

Paradise Point Resort & Spa
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,289 reviews)
The room was amazing. The restaurant service left a lot to be desired, even to the point of ignoring us and rudeness. Front desk and manager were friendly and kind, the rest of the service staff, not impressed. Lovely property, requests were honored. It is a pretty busy beach/boardwalk. We would ...

Reviewed on Oct 24, 2025

San Diego Mission Bay Resort
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8/10 Very Good! (2,107 reviews)
Didn’t use the pool but area very well maintained Only negative comment Saturday morning went to the front desk to have only our beds made . Came back to the hotel at 7:00 pm beds were not made very disappointing I did call when I came back to my room the front desk so the supervisor of my housekeeper ...

Reviewed on Oct 28, 2025

Hilton San Diego Mission Valley
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Mission ...
9/10 Wonderful! (207 reviews)
A nice, clean Hampton Inn. Everything that you would expect

Reviewed on Oct 27, 2025

Hampton Inn & Suites by Hilton San Diego SeaWorld
Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,003 reviews)
The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel.

Reviewed on Oct 22, 2025

Pendry San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...
8.8/10 Excellent! (3,029 reviews)
Staff was great. My only two complaint is. The main lobby is over powering with some type of air freshener. And also our balcony door did not lock. It is very noisy at night but you are in down town where all the night life is. It’s a nice stay for sure.

Reviewed on Oct 26, 2025

Hard Rock Hotel San Diego
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St, San Diego, CA
Fully refundable
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8/10 Very Good! (1,145 reviews)
Balcony view and healthy breakfast! Excellent customer service!

Reviewed on Oct 28, 2025

Courtyard by Marriott San Diego Downtown Little Italy
InterContinental San Diego by IHG

InterContinental San Diego by IHG

4 out of 5
901 Bayfront Court, San Diego, CA
Fully refundable
Stay at this 4-star business-friendly hotel in San Diego. Enjoy 2 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,066 reviews)
From check in to relaxing in the harbor view room and friendly staff at breakfast made the stay very memorable.

Reviewed on Oct 24, 2025

InterContinental San Diego by IHG
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (2,918 reviews)
Was a wonderful stay! The staff was very nice. The food was delicious but $$$ would stay again

Reviewed on Oct 27, 2025

Legacy Resort Hotel & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (6,000 reviews)
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Reviewed on Oct 27, 2025

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Mission Bay

San Diego is a city that has a lot going on, but you have your sights set on Mission Bay. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Mission Bay has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Mission Bay hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Mission Bay underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Mission Bay city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Mission Bay cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Mission Bay at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $122
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Mission Bay hotel you want, book it, and never look back. Because your great escape is ahead of you.