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Hotels in South Indianapolis

Choose from 2528 South Indianapolis Hotel Deals

Baymont by Wyndham Indianapolis South

Baymont by Wyndham Indianapolis South

2.5 out of 5
4402 E Creek View Rd Indianapolis IN
  • 8 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (612 reviews)
Newer hotel. Clean with a friendly staff

Reviewed on Jan 16, 2026

Baymont by Wyndham Indianapolis South
Comfort Inn Indianapolis South

Comfort Inn Indianapolis South

2.5 out of 5
5040 S East St Indianapolis IN
  • 26 min walk from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
7/10 Good! (702 reviews)
Great experience. Friendly staff! Went for a cheer comp. Would stay again!

Reviewed on Jan 20, 2026

Comfort Inn Indianapolis South
Ironworks Hotel Indy

Ironworks Hotel Indy

4 out of 5
2721 E 86th Street Indianapolis IN
  • 34 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,789 reviews)
Great place will stay again.

Reviewed on Jan 26, 2026

Ironworks Hotel Indy
Bottleworks Hotel

Bottleworks Hotel

4.5 out of 5
850 Massachusetts Avenue Indianapolis IN
  • 12 min drive from University of Indianapolis
Book a stay at this luxury hotel in Indianapolis. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.8/10 Exceptional! (1,807 reviews)
nice hotel

Reviewed on Jan 23, 2026

Bottleworks Hotel
Omni Severin Hotel

Omni Severin Hotel

4 out of 5
40 West Jackson Place Indianapolis IN
  • 9 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful ...
9.2/10 Wonderful! (816 reviews)
Nice room very quiet friendly staff

Reviewed on Jan 23, 2026

Omni Severin Hotel
Courtyard by Marriott Indianapolis Downtown

Courtyard by Marriott Indianapolis Downtown

3 out of 5
601 West Washington Street Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,042 reviews)
Courteous staff

Reviewed on Jan 23, 2026

Courtyard by Marriott Indianapolis Downtown
Courtyard by Marriott Indianapolis at the Capitol

Courtyard by Marriott Indianapolis at the Capitol

3 out of 5
320 N Senate Ave Indianapolis IN
  • 11 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (867 reviews)
Rooms were very clean and the staff were all very friendly

Reviewed on Jan 23, 2026

Courtyard by Marriott Indianapolis at the Capitol
Hilton Garden Inn Indianapolis Downtown

Hilton Garden Inn Indianapolis Downtown

3.5 out of 5
10 East Market Street Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (149 reviews)
Everything was top notch! Valet service was a plus

Reviewed on Jan 21, 2026

Hilton Garden Inn Indianapolis Downtown
Embassy Suites by Hilton Indianapolis Downtown

Embassy Suites by Hilton Indianapolis Downtown

3.5 out of 5
110 West Washington Street Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.4/10 Very Good! (1,007 reviews)
Great location! The complimentary breakfast is a must with good choices in breakfast meats, omelettes, breads, yogurts, and cereals.

Reviewed on Jan 26, 2026

Embassy Suites by Hilton Indianapolis Downtown
JW Marriott Indianapolis

JW Marriott Indianapolis

4 out of 5
10 S West Street Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests ...
9.2/10 Wonderful! (1,334 reviews)
Room was great!! Loved the hotel!

Reviewed on Jan 24, 2026

JW Marriott Indianapolis
Hyatt Regency Indianapolis

Hyatt Regency Indianapolis

4 out of 5
One South Capitol Avenue Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,007 reviews)
Kind front desk!

Reviewed on Jan 25, 2026

Hyatt Regency Indianapolis
Baymont by Wyndham Plainfield/ Indianapolis Arpt Area

Baymont by Wyndham Plainfield/ Indianapolis Arpt Area

2.5 out of 5
6010 Gateway Dr Plainfield IN
  • 17 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Plainfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,367 reviews)
Courteous staff.

Reviewed on Jan 23, 2026

Baymont by Wyndham Plainfield/ Indianapolis Arpt Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South Indianapolis

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in South Indianapolis.

Choosing the right hotel in Indiana has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South Indianapolis’s 2,528 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $80. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South Indianapolis hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South Indianapolis. No matter your reason for visiting South Indianapolis, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South Indianapolis hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South Indianapolis for as low as $80.

How many hotels are there in South Indianapolis?

With over 2,528 hotels in South Indianapolis, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $80.

How to find cheap car rentals in South Indianapolis?

Finding a cheap car rental deal in South Indianapolis is as easy as scoring cheap hotels in South Indianapolis. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.