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4 Star Hotels in Des Peres

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Featured 4 Star Des Peres Hotels

Hyatt Regency St. Louis at The Arch
4 out of 5
Fully refundableReserve now, pay when you stay
  • 30 min drive from Museum of Transportation
The price is $124 per night from Apr 18 to Apr 19
$124
per night
Apr 18 - Apr 19
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Moonrise Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 22 min drive from Museum of Transportation
The price is $159 per night from Mar 30 to Mar 31
$159
per night
Mar 30 - Mar 31
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Moonrise Hotel
River City Casino & Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 23 min drive from Museum of Transportation
The price is $114 per night from Apr 6 to Apr 7
$114
per night
Apr 6 - Apr 7
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
River City Casino & Hotel
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DoubleTree by Hilton St. Louis Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from Museum of Transportation
The price is $124 per night from Mar 30 to Mar 31
$124
per night
Mar 30 - Mar 31
Stay at this 4-star family-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
DoubleTree by Hilton St. Louis Airport
21C Museum Hotel St Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min drive from Museum of Transportation
The price is $204 per night from Apr 20 to Apr 21
$204
per night
Apr 20 - Apr 21
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
Renaissance St. Louis Airport Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from Museum of Transportation
The price is $143 per night from Mar 30 to Mar 31
$143
per night
Mar 30 - Mar 31
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Renaissance St. Louis Airport Hotel
Ameristar Casino Resort and Spa
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 33 min drive from Museum of Transportation
The price is $214 per night from Mar 31 to Apr 1
$214
per night
Mar 31 - Apr 1
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
Ameristar Casino Resort and Spa
Live by Loews - St.Louis
4 out of 5
  • 29 min drive from Museum of Transportation
The price is $201 per night from Mar 30 to Mar 31
$201
per night
Mar 30 - Mar 31
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Live by Loews - St.Louis
Le Méridien St. Louis Clayton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 min drive from Museum of Transportation
The price is $187 per night from Mar 28 to Mar 29
$187
per night
Mar 28 - Mar 29
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Le Méridien St. Louis Clayton
The Last Hotel
4.5 out of 5
  • 29 min drive from Museum of Transportation
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Last Hotel
Embassy Suites by Hilton St. Louis Downtown
4 out of 5
Fully refundableReserve now, pay when you stay
  • 30 min drive from Museum of Transportation
The price is $138 per night from Apr 6 to Apr 7
$138
per night
Apr 6 - Apr 7
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and WiFi (surcharge). Our guests praise the breakfast and the ...
Embassy Suites by Hilton St. Louis Downtown
Hilton St. Louis Frontenac
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min drive from Museum of Transportation
The price is $167 per night from Apr 6 to Apr 7
$167
per night
Apr 6 - Apr 7
Book a stay at this business-friendly hotel in Frontenac. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property ...
Hilton St. Louis Frontenac
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Des Peres

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Des Peres for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Des Peres as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Des Peres 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Des Peres starting at $114 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Des Peres 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.