Search for Cheap Deals on5 Star Hotels in Medical Center District
Photo by Linda Cronan
Check Last Minute Medical Center District Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured 5 Star Medical Center District Hotels

The price is $285 per night from Apr 13 to Apr 14
$285
includes taxes & fees
Apr 13 - Apr 14
Stay at this 5-star luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the bar and the helpful staff ...

Stay at this 5-star luxury apartment in San Antonio. Enjoy free WiFi, free parking, and balconies or patios. Popular attractions Six Flags Fiesta Texas and The ...
Don't see what you're looking for?
See all available properties in Medical Center District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Medical Center District Hotels
- La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
- San Antonio Marriott Northwest Medical Center
- Riverwalk Plaza
- La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
- Sonesta ES Suites San Antonio Downtown Alamo Plaza
- Grand Hyatt San Antonio River Walk
- Menger Hotel
- Hotel Contessa
- Spark By Hilton San Antonio Northwest near Six Flags
- Crockett Hotel
Nearby Cities
- New Braunfels Hotels (30.36 mi)
- Hill Country Hotels (68.54 mi)
- Boerne Hotels (21.98 mi)
- Gulf Coast Hotels (306.58 mi)
- Schertz Hotels (18.72 mi)
- Bulverde Hotels (18.01 mi)
- Helotes Hotels (8.4 mi)
- Spring Branch Hotels (25.15 mi)
- Castroville Hotels (20.91 mi)
- Selma Hotels (17.15 mi)
- Universal City Hotels (17.41 mi)
- Converse Hotels (15.69 mi)
Recommended cities for you
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Los Angeles Hotels
- Miami Hotels
- San Francisco Hotels
- New Orleans Hotels
- Chicago Hotels
- Fort Lauderdale Hotels
- Boston Hotels
- Honolulu Hotels
- San Diego Hotels
- Washington Hotels
- Toronto Hotels
- Anaheim Hotels
- Atlanta Hotels
- Nashville Hotels
- Seattle Hotels
- Phoenix Hotels
- Myrtle Beach Hotels
Car Rentals Near Medical Center District
- Car rentals in New Braunfels
- Car rentals in Hill Country
- Car rentals in Boerne
- Car rentals in Gulf Coast
- Car rentals in Schertz
- Car rentals in Bulverde
- Car rentals in Helotes
- Car rentals in Spring Branch
- Car rentals in Castroville
- Car rentals in Selma
- Car rentals in Universal City
- Car rentals in Converse
- Car rentals in Cibolo
- Car rentals in Elmendorf
- Car rentals in Pipe Creek
- Car rentals in South Texas