Search for Cheap Deals on
5 Star Hotels in Medical Center District

Photo by Linda Cronan

Check Last Minute Medical Center District Hotel Deals

Tonight Mar 25 - Mar 26This weekend Mar 28 - Mar 30Next weekend Apr 4 - Apr 6

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!

Featured 5 Star Medical Center District Hotels

Thompson San Antonio - Riverwalk, by Hyatt
5 out of 5
  • 19 min drive from USAA Corporate Office Headquarters
The price is $285 per night from Apr 13 to Apr 14
$285
includes taxes & fees
Apr 13 - Apr 14
Stay at this 5-star luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the bar and the helpful staff ...
Thompson San Antonio - Riverwalk, by Hyatt
The Luxury Suites at Arrive Eilan
5 out of 5
  • 12 min drive from USAA Corporate Office Headquarters
Stay at this 5-star luxury apartment in San Antonio. Enjoy free WiFi, free parking, and balconies or patios. Popular attractions Six Flags Fiesta Texas and The ...
Get rates
The Luxury Suites at Arrive Eilan
Don't see what you're looking for?
See all available properties in Medical Center District
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.