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Featured 4 Star Medical Center District Hotels

Fully refundableReserve now, pay when you stay
The price is $202 per night from Feb 21 to Feb 22
$202
includes taxes & fees
Feb 21 - Feb 22
Stay at this 4-star business-friendly hotel in San Antonio. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
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Fully refundableReserve now, pay when you stay
The price is $152 per night from Feb 23 to Feb 24
$152
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the ...
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Fully refundableReserve now, pay when you stay
The price is $195 per night from Feb 23 to Feb 24
$195
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
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
Fully refundableReserve now, pay when you stay
The price is $247 per night from Feb 27 to Feb 28
$247
includes taxes & fees
Feb 27 - Feb 28
Stay at this 4-star spa hotel in San Antonio. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ...

Fully refundableReserve now, pay when you stay
The price is $362 per night from Mar 5 to Mar 6
$362
includes taxes & fees
Mar 5 - Mar 6
Stay at this 4-star eco-certified hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean ...

Fully refundableReserve now, pay when you stay
The price is $289 per night from Mar 9 to Mar 10
$289
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star spa hotel in San Antonio. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the bar and the helpful staff in our ...
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Fully refundableReserve now, pay when you stay
The price is $160 per night from Feb 23 to Feb 24
$160
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star business-friendly hotel in San Antonio. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...

Fully refundableReserve now, pay when you stay
The price is $222 per night from Mar 9 to Mar 10
$222
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star eco-certified hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful staff ...
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Fully refundableReserve now, pay when you stay
The price is $179 per night from Feb 21 to Feb 22
$179
includes taxes & fees
Feb 21 - Feb 22
Stay at this 4-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...

Fully refundableReserve now, pay when you stay
The price is $99 per night from Feb 23 to Feb 24
$99
includes taxes & fees
Feb 23 - Feb 24
Book a stay at this business-friendly hotel in San Antonio. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
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Fully refundableReserve now, pay when you stay
The price is $209 per night from Feb 23 to Feb 24
$209
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the bar and the helpful ...

Fully refundableReserve now, pay when you stay
The price is $234 per night from Feb 27 to Feb 28
$234
includes taxes & fees
Feb 27 - Feb 28
Stay at this 4-star business-friendly hotel in San Antonio. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests ...
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See all available properties in Medical Center District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Medical Center District Hotels
Top Attractions in Medical Center District
- Hotels near USAA Corporate Office Headquarters (2.34 mi)
- Hotels near South Texas Medical Center (0.35 mi)
- Hotels near University of Texas Health and Science Center at San Antonio (0.21 mi)
- Hotels near CHRISTUS Santa Rosa Hospital - Medical Center (0.86 mi)
- Hotels near Oak Hills Country Club (0.83 mi)
- Hotels near The San Antonio Art Institute (1.96 mi)
- Hotels near River Walk (7.85 mi)
- Hotels near Lackland Air Force Base (8.68 mi)
- Hotels near Six Flags Fiesta Texas (6.74 mi)
- Hotels near Alamo (7.78 mi)
- Hotels near San Antonio River (7.6 mi)
- Hotels near Henry B. González Convention Center (7.98 mi)
- Hotels near San Antonio Zoo and Aquarium (6.87 mi)
- Hotels near Alamodome (8.61 mi)
- Hotels near The Shops of La Cantera (6.41 mi)
- Hotels near Frost Bank Center (9.97 mi)
- Hotels near The Rim Shopping Center (7.16 mi)
Nearby Cities
- New Braunfels Hotels (30.36 mi)
- Hill Country Hotels (68.54 mi)
- Boerne Hotels (21.98 mi)
- Gulf Coast Hotels (306.58 mi)
- Schertz Hotels (18.72 mi)
- Helotes Hotels (8.4 mi)
- Bulverde Hotels (18.01 mi)
- Spring Branch Hotels (25.15 mi)
- Castroville Hotels (20.91 mi)
- Converse Hotels (15.69 mi)
- Selma Hotels (17.15 mi)
- Universal City Hotels (17.41 mi)
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