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5 Star Hotels in Panama Canal Zone

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Featured 5 Star Panama Canal Zone Hotels

Hotel Riu Plaza Panama
5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Albrook Shopping Mall
The price is $131 per night from Feb 26 to Feb 27
$131
includes taxes & fees
Feb 26 - Feb 27
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel Riu Plaza Panama
Waldorf Astoria Panama
5 out of 5
  • 4 min drive from Albrook Shopping Mall
The price is $166 per night from Feb 28 to Mar 1
$166
includes taxes & fees
Feb 28 - Mar 1
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Waldorf Astoria Panama
W Panama
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from Albrook Shopping Mall
The price is $158 per night from Mar 1 to Mar 2
$158
includes taxes & fees
Mar 1 - Mar 2
Stay at this 5-star luxury hotel in Panama City. Enjoy 2 restaurants, 3 spa tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
W Panama
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Hilton Panama
5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Albrook Shopping Mall
The price is $167 per night from Mar 1 to Mar 2
$167
includes taxes & fees
Mar 1 - Mar 2
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
Hilton Panama
JW Marriott Panama
5 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from Albrook Shopping Mall
The price is $241 per night from Feb 27 to Feb 28
$241
includes taxes & fees
Feb 27 - Feb 28
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
The Westin Playa Bonita Panama
5 out of 5
  • 13 min drive from Albrook Shopping Mall
The price is $202 per night from Feb 28 to Mar 1
$202
includes taxes & fees
Feb 28 - Mar 1
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
The Westin Playa Bonita Panama
Sofitel Legend Casco Viejo, Panama City
5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Albrook Shopping Mall
The price is $411 per night from Feb 4 to Feb 5
$411
includes taxes & fees
Feb 4 - Feb 5
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
Sofitel Legend Casco Viejo, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5 out of 5
Fully refundableReserve now, pay when you stay
  • 18 min drive from Albrook Shopping Mall
The price is $208 per night from Feb 21 to Feb 22
$208
includes taxes & fees
Feb 21 - Feb 22
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Bristol Panama, a Registry Collection Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from Albrook Shopping Mall
The price is $177 per night from Mar 1 to Mar 2
$177
includes taxes & fees
Mar 1 - Mar 2
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
Bristol Panama, a Registry Collection Hotel
Renaissance Panama City Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from Albrook Shopping Mall
The price is $131 per night from Feb 7 to Feb 8
$131
includes taxes & fees
Feb 7 - Feb 8
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a casino. Popular attractions Multiplaza Pacific Mall and Cinta Costera ...
Renaissance Panama City Hotel
Veneto Hotel & Casino
5 out of 5
  • 5 min drive from Albrook Shopping Mall
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Multiplaza Pacific Mall and ...
Veneto Hotel & Casino
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5-Star Hotel in Panama Canal Zone

It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in Panama Canal Zone.

So nice you’ll blink twice

What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.

Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.

Stars in your eyes

Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in Panama Canal Zone for you. Sort by:

  • Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $131.

  • Amenities: Panama Canal Zone skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.

When you’re looking for the top 5-star hotels in Panama Canal Zone—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on Panama Canal Zone your way.