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4 Star Hotels in Panama Canal Zone

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Featured 4 Star Panama Canal Zone Hotels

Decapolis Hotel Panama City
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Albrook Shopping Mall
The price is $143 per night from Jan 3 to Jan 4
$143
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Decapolis Hotel Panama City
Crowne Plaza Panama Airport, an IHG Hotel
4 out of 5
Fully refundable
  • 30 min drive from Albrook Shopping Mall
The price is $141 per night from Jan 4 to Jan 5
$141
includes taxes & fees
Jan 4 - Jan 5, 2025
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
Crowne Plaza Panama Airport, an IHG Hotel
Novotel Panama City
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Albrook Shopping Mall
The price is $97 per night from Jan 22 to Jan 23
$97
includes taxes & fees
Jan 22 - Jan 23, 2025
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Novotel Panama City
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Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from Albrook Shopping Mall
The price is $103 per night from Jan 4 to Jan 5
$103
includes taxes & fees
Jan 4 - Jan 5, 2025
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Riande Aeropuerto Hotel & Casino
4 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min drive from Albrook Shopping Mall
The price is $134 per night from Dec 29 to Dec 30
$134
includes taxes & fees
Dec 29 - Dec 30
Stay at this 4-star family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Riande Aeropuerto Hotel & Casino
Sheraton Grand Panama
4 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from Albrook Shopping Mall
The price is $158 per night from Jan 11 to Jan 12
$158
includes taxes & fees
Jan 11 - Jan 12, 2025
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Sheraton Grand Panama
Residence Inn by Marriott Panama City
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from Albrook Shopping Mall
The price is $140 per night from Jan 11 to Jan 12
$140
includes taxes & fees
Jan 11 - Jan 12, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Residence Inn by Marriott Panama City
Marriott Panama Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min walk from Albrook Shopping Mall
The price is $157 per night from Jan 3 to Jan 4
$157
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Marriott Panama Hotel
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from Albrook Shopping Mall
The price is $140 per night from Jan 3 to Jan 4
$140
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Ramada Plaza By Wyndham Panama Punta Pacífica
Megapolis Hotel Panamá
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from Albrook Shopping Mall
The price is $165 per night from Dec 30 to Dec 31
$165
includes taxes & fees
Dec 30 - Dec 31
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Megapolis Hotel Panamá
Las Americas Golden Tower Panama
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from Albrook Shopping Mall
The price is $188 per night from Jan 13 to Jan 14
$188
includes taxes & fees
Jan 13 - Jan 14, 2025
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Las Americas Golden Tower Panama
Studio Coliving
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from Albrook Shopping Mall
The price is $61 per night from Jan 2 to Jan 3
$61
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
Studio Coliving
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Panama Canal Zone

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Panama Canal Zone for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Panama Canal Zone as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Panama Canal Zone 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Panama Canal Zone starting at $61 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Panama Canal Zone 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.