Adults Only Resorts & Hotels in
Central San Diego

Check Last Minute Central San Diego Hotel Deals

Tonight Nov 3 - Nov 4Next weekend Nov 8 - Nov 10

Featured Central San Diego Adults Only Resorts & Hotels

Best Western Seven Seas
Best Western Seven Seas
3 out of 5
411 Hotel Circle South, San Diego, CA
The price is $105 per night from Nov 4 to Nov 5
$105
includes taxes & fees
Nov 4 - Nov 5
Best Western Seven Seas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Central San Diego

San Diego is a city that has a lot going on, but you have your sights set on Central San Diego. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Central San Diego has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Central San Diego hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Central San Diego underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Central San Diego city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Central San Diego cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Central San Diego at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $105
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Central San Diego hotel you want, book it, and never look back. Because your great escape is ahead of you.