Search Cheap Flights toDefiance
Search 400 airlines and 321,000 hotels worldwide.
Stop Planning & Start Exploring
FREE 24 hour cancellation on most flights
Cheap Flights to Defiance
Fall in love at first flight with your vacation to Defiance by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Defiance on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Defiance, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Defiance
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Defiance with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the STL airport.
What is the cheapest month to fly to Defiance?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Defiance are in , but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Defiance?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find to choose from for your flight to Defiance.
What airport is best to fly into Defiance?
When you’re planning your trip to Defiance, convenience is the name of the game. Luckily, Defiance Spirit of St. Louis Airport is nearby so you can deplane and get going on checking off everything on your Defiance must-do list.
How much are flights to Defiance?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Defiance on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Defiance?
The trick to saving a stack of cash on your flight to Defiance? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as right now, why wait?
Destination airport | Defiance |
---|---|
Destination airport IATA code | STL |
Last Minute Hotel Deals in Defiance

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
We made a last minute reservation and were pleased with the value. It’s not the newest hotel but we got a spacious two room suite for a great price.
Reviewed on Oct 17, 2025

Hollywood Casino & Hotel St. Louis
Great stay would recommend
Reviewed on Oct 16, 2025

Hilton St. Louis Frontenac
Excellent staff, quiet rooms, good food options and bar on site
Reviewed on Oct 19, 2025

Crowne Plaza St. Louis Airport by IHG
Friendly staff
Reviewed on Oct 17, 2025

Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Staff was best I have ever encountered. The hotel was old but clean. Great experience.
Reviewed on Oct 19, 2025

Hampton Inn St. Charles St. Peters
The staff was friendly and pleasant. The room was clean. The pool was VERY cold and the whirlpool was VERY warm. The breakfast was typical, nothing special but the dining area was way too crowded.
Reviewed on Oct 19, 2025

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Dirty and had roaches
Reviewed on Oct 18, 2025

Courtyard by Marriott St Louis Creve Coeur
Didn’t eat. Just coffee and it was great!
Reviewed on Oct 19, 2025
Nearby Cities
Popular Flight Routes
- Atlanta to New York
- Detroit to Las Vegas
- Dallas to Atlanta
- Dallas to Yosemite National Park
- Toronto to Edmonton
- Chicago to Tulum
- Houston to Lake Tahoe
- Chicago to Las Vegas
- Dallas to Miami
- Dallas to Lake Tahoe
- New York to Miami
- New York to Las Vegas
- Miami to Atlanta
- Minneapolis St Paul to Fort Walton Beach Destin
- Dallas to Branson
- Cleveland to Vero Beach
- Managua to Miami
- Atlanta to Boston
- Austin to Tulum
- Calgary to Vancouver