Search Cheap Flights to
Defiance

Name: La Quinta Inn & Suites by Wyndham St. Louis Westport
Rating: 7.2

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Defiance Flights as Low as $70

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

All deals

One way

Roundtrip

Thu, Aug 21 - Thu, Aug 28

DFW

Dallas-Fort Worth Intl.

STL

Lambert-St. Louis Intl.

$70

Roundtrip

found 1 day ago

Thu, Aug 21 - Sun, Aug 24

DFW

Dallas-Fort Worth Intl.

STL

Lambert-St. Louis Intl.

$72

Roundtrip

found 1 day ago

Sat, Aug 2 - Thu, Aug 7

ATL

Hartsfield-Jackson Atlanta Intl.

STL

Lambert-St. Louis Intl.

$81

Roundtrip

found 22 hours ago

Thu, Aug 7 - Thu, Aug 14

ATL

Hartsfield-Jackson Atlanta Intl.

STL

Lambert-St. Louis Intl.

$87

Roundtrip

found 3 hours ago

Thu, Sep 18 - Mon, Sep 22

ATL

Hartsfield-Jackson Atlanta Intl.

STL

Lambert-St. Louis Intl.

$97

Roundtrip

found 5 hours ago

Thu, Dec 11 - Sat, Dec 13

FLL

Fort Lauderdale - Hollywood Intl.

STL

Lambert-St. Louis Intl.

$98

Roundtrip

found 1 day ago

Mon, Aug 25 - Thu, Sep 4

EWR

Newark Liberty Intl. Airport

STL

Lambert-St. Louis Intl.

$140

Roundtrip

found 14 hours ago

Sat, Sep 6 - Thu, Sep 11

BWI

Baltimore Washington Intl. Thurgood Marshall

STL

Lambert-St. Louis Intl.

$143

Roundtrip

found 1 day ago

Thu, Oct 2 - Fri, Oct 10

ATL

Hartsfield-Jackson Atlanta Intl.

STL

Lambert-St. Louis Intl.

$147

Roundtrip

found 1 day ago

Thu, Aug 21 - Mon, Aug 25

DFW

Dallas-Fort Worth Intl.

STL

Lambert-St. Louis Intl.

$160

Roundtrip

found 1 day ago

Tue, Sep 2 - Thu, Sep 4

LGA

LaGuardia

STL

Lambert-St. Louis Intl.

$177

Roundtrip

found 18 hours ago

Tue, Nov 11 - Tue, Nov 18

AUS

Austin-Bergstrom Intl.

STL

Lambert-St. Louis Intl.

$177

Roundtrip

found 21 hours ago

Sat, Aug 30 - Tue, Sep 2

CLE

Hopkins Intl.

STL

Lambert-St. Louis Intl.

$189

Roundtrip

found 16 hours ago

Sat, Nov 8 - Tue, Nov 18

AUS

Austin-Bergstrom Intl.

STL

Lambert-St. Louis Intl.

$196

Roundtrip

found 6 days ago

Tue, Oct 14 - Tue, Oct 21

DAL

Love Field

STL

Lambert-St. Louis Intl.

$197

Roundtrip

found 1 day ago

Wed, Aug 27 - Wed, Sep 3

CHS

Charleston Intl.

STL

Lambert-St. Louis Intl.

$227

Roundtrip

found 1 day ago

Cheap Flights to Defiance

Fall in love at first flight with your vacation to Defiance by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Defiance on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Defiance, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Defiance

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Defiance with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Defiance?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Defiance are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Defiance?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Defiance.

What airport is best to fly into Defiance?

When you’re planning your trip to Defiance, convenience is the name of the game. Luckily, Defiance Spirit of St. Louis Airport is nearby so you can deplane and get going on checking off everything on your Defiance must-do list.

How much are flights to Defiance?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Defiance on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $70, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Defiance?

The trick to saving a stack of cash on your flight to Defiance? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $70 right now, why wait?

Defiance Flight Information
Destination airport	Lambert-St. Louis Intl.
Destination airport IATA code	STL
Roundtrip price	$70

Last Minute Hotel Deals in Defiance

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

1088 South Highway Drive, Fenton, MO

Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

8.4/10 Very Good! (1,028 reviews)

"Very out of the way. Not close to amenities."

Reviewed on Jul 24, 2025

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Hollywood Casino & Hotel St. Louis

777 Casino Center Drive, Maryland Heights, MO

Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...

8.2/10 Very Good! (2,021 reviews)

"Staff at hotel and shuttle to concert was excellent"

Reviewed on Jul 26, 2025

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Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd, Maryland Heights, MO

Stay at this hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...

4.4/10 (1,015 reviews)

Needs cleaning

"We where given a dirty room at 1st but got another room..."

Reviewed on Jul 18, 2025

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Wingate by Wyndham St. Louis/Fenton Route 66

1100 S Highway Dr, Fenton, MO

Stay at this 3-star business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

8.2/10 Very Good! (1,027 reviews)

"Hallway carpets seriously dirty. Check in person very nice."

Reviewed on Jul 23, 2025

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Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

13639 Riverport Dr, Maryland Heights, MO

Stay at this 3-star business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...

7.2/10 Good! (1,034 reviews)

"Good service"

Reviewed on Jul 26, 2025

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Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO

Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...

8.2/10 Very Good! (1,018 reviews)

"The hotel room was comfortable and well-kept - it’s a good spot for a weekend getaway or a night before flying out from the airport. Good mix of slots and tables."

Reviewed on Jul 24, 2025

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The Wildwood Hotel

2801 Fountain Pl, Wildwood, MO

Stay at this 3.5-star business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...

9/10 Wonderful! (1,563 reviews)

"I had a wonderful stay and will stay there again in the future."

Reviewed on Jul 25, 2025

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La Quinta Inn & Suites by Wyndham St. Louis Westport

11805 Lackland Rd, Maryland Heights, MO

Stay at this 3-star business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

7.2/10 Good! (1,026 reviews)

"Family friendly"

Reviewed on Jul 26, 2025

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See all 841 properties in Defiance

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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