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Hotels in Defiance

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Tonight Sep 22 - Sep 23Next weekend Sep 27 - Sep 29

Choose from 833 Defiance Hotel Deals

Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
  • 35 min drive from Chandler Hill Vineyards
The price is $137 per night from Oct 6 to Oct 7
$137
includes taxes & fees
Oct 6 - Oct 7
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,565 reviews)
"Excellent property free parking is always a very nice perk!!!"

Reviewed on Sep 15, 2024

Hollywood Casino & Hotel St. Louis
Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - Chesterfield
3 out of 5
15431 Conway Rd, Chesterfield, MO
  • 25 min drive from Chandler Hill Vineyards
The price is $100 per night from Oct 20 to Oct 21
$100
includes taxes & fees
Oct 20 - Oct 21
Stay at this hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,004 reviews)
"Very good"

Reviewed on Sep 17, 2024

Sonesta ES Suites St. Louis - Chesterfield
The Wildwood Hotel
The Wildwood Hotel
3.5 out of 5
2801 Fountain Pl, Wildwood, MO
  • 20 min drive from Chandler Hill Vineyards
The price is $107 per night from Sep 29 to Sep 30
$107
includes taxes & fees
Sep 29 - Sep 30
Stay at this 3.5-star business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...
8.8/10 Excellent! (1,392 reviews)
"Very nice establishment."

Reviewed on Sep 17, 2024

The Wildwood Hotel
La Quinta Inn & Suites by Wyndham St. Louis Westport
La Quinta Inn & Suites by Wyndham St. Louis Westport
2.5 out of 5
11805 Lackland Rd, Maryland Heights, MO
  • 36 min drive from Chandler Hill Vineyards
The price is $90 per night from Oct 3 to Oct 4
$90
includes taxes & fees
Oct 3 - Oct 4
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.2/10 Good! (1,005 reviews)
"Plenty of parking, and was happy to find lots of good food close by. Living in California, there is no White Castle, so I was overjoyed to find it a 7 minute drive away from here. Also found a Filipino bakery 7 minutes away as well. A great place close by great food and half an hour drive away from ..."

Reviewed on Sep 20, 2024

La Quinta Inn & Suites by Wyndham St. Louis Westport
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
  • 36 min drive from Chandler Hill Vineyards
The price is $236 per night from Sep 23 to Sep 24
$236
includes taxes & fees
Sep 23 - Sep 24
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 5 restaurants. Our guests praise the clean rooms and the property ...
8.2/10 Very Good! (1,004 reviews)
"I found the room to be great, the parking and check in easy and the location was very good. I did not use the casino or restaurant so I can't report on those areas."

Reviewed on Sep 18, 2024

Ameristar Casino Resort and Spa
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
2.5 out of 5
1970 Craig Rd, Maryland Heights, MO
  • 36 min drive from Chandler Hill Vineyards
The price is $69 per night from Sep 29 to Sep 30
$69
includes taxes & fees
Sep 29 - Sep 30
Stay at this hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
4.6/10 (1,002 reviews)
"Quite and great customer service"

Reviewed on Sep 11, 2024

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Crowne Plaza St. Louis Airport, an IHG Hotel
Crowne Plaza St. Louis Airport, an IHG Hotel
3.5 out of 5
11228 Lone Eagle Dr, Bridgeton, MO
  • 41 min drive from Chandler Hill Vineyards
The price is $132 per night from Sep 26 to Sep 27
$132
includes taxes & fees
Sep 26 - Sep 27
Stay at this 3.5-star business-friendly hotel in Bridgeton. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.8/10 Good! (1,005 reviews)
"Just the restroom bit dirty :("

Reviewed on Sep 20, 2024

Crowne Plaza St. Louis Airport, an IHG Hotel
Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis Chesterfield
3 out of 5
355 Chesterfield Ctr, Chesterfield, MO
  • 24 min drive from Chandler Hill Vineyards
The price is $136 per night from Sep 29 to Sep 30
$136
includes taxes & fees
Sep 29 - Sep 30
Stay at this 3-star business-friendly hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,000 reviews)
"Convenient, with a great pool for the kids."

Reviewed on Sep 15, 2024

Drury Plaza Hotel St. Louis Chesterfield
Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-Westport
2.5 out of 5
12220 Dorsett Rd, Maryland Heights, MO
  • 36 min drive from Chandler Hill Vineyards
The price is $93 per night from Oct 2 to Oct 3
$93
includes taxes & fees
Oct 2 - Oct 3
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,003 reviews)
"The hotel was clean and comfortable. Breakfast was not bad it had sat for a bit before we got there."

Reviewed on Sep 13, 2024

Best Western Plus St. Louis West-Westport
Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66
2.5 out of 5
1100 S Highway Dr, Fenton, MO
  • 38 min drive from Chandler Hill Vineyards
The price is $83 per night from Oct 1 to Oct 2
$83
includes taxes & fees
Oct 1 - Oct 2
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,003 reviews)
"Nice place"

Reviewed on Sep 15, 2024

Wingate by Wyndham St. Louis/Fenton Route 66
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
3.5 out of 5
2 Convention Center Plz, St. Charles, MO
  • 35 min drive from Chandler Hill Vineyards
The price is $146 per night from Sep 29 to Sep 30
$146
includes taxes & fees
Sep 29 - Sep 30
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,158 reviews)
"Love it great customer service I got to hotel so much in one year ?"

Reviewed on Sep 2, 2024

Embassy Suites by Hilton St. Louis St. Charles
Country Inn & Suites by Radisson, St. Charles, MO
Country Inn & Suites by Radisson, St. Charles, MO
2.5 out of 5
1190 S Main St, St. Charles, MO
  • 36 min drive from Chandler Hill Vineyards
The price is $121 per night from Sep 29 to Sep 30
$121
includes taxes & fees
Sep 29 - Sep 30
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
"It was very good minus the air not working properly as the room temp never went below 70 all weekend"

Reviewed on Sep 15, 2024

Country Inn & Suites by Radisson, St. Charles, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Defiance

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Defiance hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Defiance.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Defiance’s 833 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Defiance hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Defiance. No matter your reason for visiting Defiance, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Defiance hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Defiance for as low as $69.

How many hotels are there in Defiance?

With over 833 hotels in Defiance, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.

How to find cheap car rentals in Defiance?

Finding a cheap car rental deal in Defiance is as easy as scoring cheap hotels in Defiance. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Defiance now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Defiance right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.