Search for Cheap Deals on
Luxury Hotels in Downtown St. Louis

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Luxury Downtown St. Louis

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
5 out of 5
999 North Second Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in St. Louis. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
Four Seasons Hotel St Louis
The Westin St. Louis
The Westin St. Louis
4.5 out of 5
811 Spruce St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and valet parking (surcharge). Our guests praise the helpful ...
The Westin St. Louis
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Drury Plaza Hotel St. Louis at the Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4 out of 5
421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
1820 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
St. Louis Union Station Hotel, Curio Collection by Hilton
Missouri Athletic Club
Missouri Athletic Club
3.5 out of 5
405 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
Missouri Athletic Club
Le Meridien St. Louis Downtown
Le Meridien St. Louis Downtown
4 out of 5
1019 Pine St, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful ...
Le Meridien St. Louis Downtown
Pear Tree Inn St. Louis Near Union Station
Pear Tree Inn St. Louis Near Union Station
3 out of 5
2211 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Pear Tree Inn St. Louis Near Union Station
OYO Hotel St. Louis Downtown City Center MO
OYO Hotel St. Louis Downtown City Center MO
3.5 out of 5
400 S 14th St, St. Louis, MO
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
OYO Hotel St. Louis Downtown City Center MO
Embassy Suites by Hilton St. Louis Downtown
Embassy Suites by Hilton St. Louis Downtown
4 out of 5
610 N 7th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and WiFi (surcharge). Our guests praise the breakfast and the ...
Embassy Suites by Hilton St. Louis Downtown
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Hilton St. Louis at the Ballpark
Hilton St. Louis at the Ballpark
4 out of 5
1 S Broadway, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy 3 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the clean rooms in our ...
Hilton St. Louis at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.