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DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
  • 7 min drive from East Houston Regional Med Center
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,026 reviews)
The room had a balcony

Reviewed on May 15, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
  • 9 min drive from East Houston Regional Med Center
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,006 reviews)
No breakfast instead a good coffee bar

Reviewed on May 12, 2026

Hotel Zaza Houston Museum District
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
  • 27 min walk from East Houston Regional Med Center
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (4,176 reviews)
Unique ipad self checkin with you creating your own room key. Rooms are tiny but bed was comfy and room was clean. I opted for add on breakfast and portion and presentation were worth the extra 12 dollars. Keep in mind there is no fridge in room. Air-conditioning works really well. Hall and room ...

Reviewed on May 16, 2026

Club Quarters Hotel Downtown, Houston
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
  • 4 min drive from East Houston Regional Med Center
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,184 reviews)
We had a great stay, everyone was friendly and helpful, the rooms were clean, and the family had a blast hanging out by the pool while the kids played.

Reviewed on May 16, 2026

The Whitehall Houston
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
  • 13 min drive from East Houston Regional Med Center
Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (3,812 reviews)
Very lovely hotel that we just discovered. It was like a luxury botique hotel where the staff treated guests like loving family. We loved all the details that really upgraded our stay. The food was wonderful as well. We particularily loved our waiter at breakfast, Oscar. We will definitely ...

Reviewed on May 16, 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
  • 6 min drive from East Houston Regional Med Center
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,911 reviews)
The breakfast was nice and the rooms were well maintained however breakfast was Alittle expensive but it was very delicious

Reviewed on May 16, 2026

The Royal Sonesta Houston Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
  • 11 min drive from East Houston Regional Med Center
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (1,914 reviews)
Breakfast was wonderful and the front desk staff were very helpful.

Reviewed on May 16, 2026

Hilton Houston Plaza/Medical Center
Grand Tuscany Hotel

Grand Tuscany Hotel

4 out of 5
12801 Northwest Fwy Houston TX
  • 12 min drive from East Houston Regional Med Center
Book a stay at this family-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the pool and the helpful ...
7.4/10 Good! (46 reviews)
Room smelt like fee. It was very disturbing. Stains on the sheets, glad I always bring my own. The building itself is nice but it needs a lot of improvement

Reviewed on May 16, 2026

Grand Tuscany Hotel
La Quinta Inn & Suites by Wyndham Houston Bush IAH South

La Quinta Inn & Suites by Wyndham Houston Bush IAH South

3 out of 5
15510 JFK Blvd Houston TX
  • 28 min drive from East Houston Regional Med Center
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
Marriott Marquis Houston

Marriott Marquis Houston

4 out of 5
1777 Walker Street Houston TX
  • 4 min drive from East Houston Regional Med Center
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,101 reviews)
My friend and I were underwhelmed with the hotel although Spencer at the check-in counter was very pleasant and helpful. The pool which was the primary highlight of the trip but swimming at night was not a good experience. The water was so cold. You would think for a luxury hotel with a luxury price, ...

Reviewed on May 14, 2026

Marriott Marquis Houston
Great Wolf Lodge Webster

Great Wolf Lodge Webster

2 out of 5
1000 Great Wolf Wy Webster TX
  • 43 min drive from East Houston Regional Med Center
Book a stay at this family-friendly hotel in Webster. Enjoy free WiFi, 5 restaurants, and 3 bars/lounges. Popular attractions Space Center Houston and Kemah ...
9/10 Wonderful! (317 reviews)
Great place to stay!

Reviewed on May 16, 2026

Great Wolf Lodge Webster
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4 out of 5
1100 Texas St Houston TX
  • 26 min walk from East Houston Regional Med Center
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9.2/10 Wonderful! (1,520 reviews)
Everything was so nice, clean and very vintage. Would definitely stay there again.

Reviewed on May 14, 2026

Magnolia Hotel Houston, A Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in East Houston

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Frequently Asked Questions About East Houston hotels

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How many hotels are there in East Houston?

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Finding a cheap car rental deal in East Houston is as easy as scoring cheap hotels in East Houston. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.