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Hotels in East Houston

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Tonight Mar 21 - Mar 22This weekend Mar 21 - Mar 23

Choose from 6320 East Houston Hotel Deals

Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
  • 26 min walk from East Houston Regional Med Center
The price is $125 per night from Apr 6 to Apr 7
$125
includes taxes & fees
Apr 6 - Apr 7
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,141 reviews)
"Great stay"

Reviewed on Mar 19, 2025

Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
  • 7 min drive from East Houston Regional Med Center
The price is $169 per night from Mar 28 to Mar 29
$169
includes taxes & fees
Mar 28 - Mar 29
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,844 reviews)
"Great employees"

Reviewed on Mar 19, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
  • 4 min drive from East Houston Regional Med Center
The price is $167 per night from Mar 30 to Mar 31
$167
includes taxes & fees
Mar 30 - Mar 31
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,288 reviews)
"Very friendly staff. I loved it there. I would stay there again."

Reviewed on Mar 19, 2025

The Whitehall Houston
Sonesta Hotel Houston IAH Airport
Sonesta Hotel Houston IAH Airport
4 out of 5
425 North Sam Houston Parkway East, Houston, TX
  • 28 min drive from East Houston Regional Med Center
The price is $83 per night from Mar 25 to Mar 26
$83
includes taxes & fees
Mar 25 - Mar 26
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
7.4/10 Good! (1,002 reviews)
Enjoyed my Stay
"The parking lot has round the clock security to ensure that our vehicle is safe. The room was very clean and I also liked the fact that they have a restaurant inside."

Reviewed on Mar 17, 2025

Sonesta Hotel Houston IAH Airport
Holiday Inn Houston Downtown by IHG
Holiday Inn Houston Downtown by IHG
3 out of 5
1616 Main St, Houston, TX
  • 4 min drive from East Houston Regional Med Center
The price is $160 per night from Mar 27 to Mar 28
$160
includes taxes & fees
Mar 27 - Mar 28
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,083 reviews)
"Ok"

Reviewed on Mar 19, 2025

Holiday Inn Houston Downtown by IHG
Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
  • 13 min drive from East Houston Regional Med Center
The price is $180 per night from Mar 23 to Mar 24
$180
includes taxes & fees
Mar 23 - Mar 24
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,177 reviews)
Great Location, Beautiful Hotel.
"The stay was excellent. The only issue was being charged twice for valet when we only had one vehicle Everything related to the room and service was awesome. We wouldn't stay anywhere else when in Houston."

Reviewed on Mar 19, 2025

Blossom Hotel Houston
The Royal Sonesta Houston Galleria
The Royal Sonesta Houston Galleria
4 out of 5
2222 West Loop South, Houston, TX
  • 6 min drive from East Houston Regional Med Center
The price is $221 per night from Apr 4 to Apr 5
$221
includes taxes & fees
Apr 4 - Apr 5
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,008 reviews)
"Great staff and beautiful property"

Reviewed on Mar 19, 2025

The Royal Sonesta Houston Galleria
Hyatt Place Houston-North
Hyatt Place Houston-North
3.5 out of 5
300 Ronan Park Place, Houston, TX
  • 28 min drive from East Houston Regional Med Center
The price is $80 per night from Apr 13 to Apr 14
$80
includes taxes & fees
Apr 13 - Apr 14
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
6.6/10 (912 reviews)
"Great stay. No complaints"

Reviewed on Mar 18, 2025

Hyatt Place Houston-North
Houston Marriott Westchase
Houston Marriott Westchase
4 out of 5
2900 Briarpark Dr, Houston, TX
  • 8 min drive from East Houston Regional Med Center
The price is $121 per night from Apr 5 to Apr 6
$121
includes taxes & fees
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8/10 Very Good! (1,006 reviews)
"Definitely a pleasure being here! Ms Joan did an outstanding job on helping me make my lady birthday perfect she loved everything thank yall again so much"

Reviewed on Mar 19, 2025

Houston Marriott Westchase
Hilton Americas-Houston
Hilton Americas-Houston
4 out of 5
1600 Lamar Street, Houston, TX
  • 4 min drive from East Houston Regional Med Center
The price is $210 per night from Apr 5 to Apr 6
$210
includes taxes & fees
Apr 5 - Apr 6
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,199 reviews)
"."

Reviewed on Mar 19, 2025

Hilton Americas-Houston
Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum District
4.5 out of 5
5701 Main Street, Houston, TX
  • 9 min drive from East Houston Regional Med Center
The price is $381 per night from Mar 30 to Mar 31
$381
includes taxes & fees
Mar 30 - Mar 31
Stay at this 4.5-star luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
8.8/10 Excellent! (1,617 reviews)
"Zaza customer service is top notch! There attention to detail is on point! Love staying here. Highly recommend this hotel!"

Reviewed on Mar 14, 2025

Hotel Zaza Houston Museum District
Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical Center
3.5 out of 5
8686 Kirby Drive, Houston, TX
  • 16 min drive from East Houston Regional Med Center
The price is $146 per night from Apr 1 to Apr 2
$146
includes taxes & fees
Apr 1 - Apr 2
Stay at this 3.5-star business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Our guests praise the helpful ...
7.2/10 Good! (1,018 reviews)
"Conveniently located. Older property that could be a little better kept."

Reviewed on Mar 19, 2025

Wyndham Houston near NRG Park/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in East Houston

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $80. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great East Houston hotel deals at the last minute.

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Frequently Asked Questions About East Houston hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in East Houston?

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Finding a cheap car rental deal in East Houston is as easy as scoring cheap hotels in East Houston. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.