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Featured Panhandle Plains Family Hotels

Hawthorn Suites by Wyndham Lubbock
4435 Marsha Sharp Fwy, Lubbock, TX
Stay at this 3-star business-friendly hotel in Lubbock. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean ...

MCM Elegante Suites Abilene
4250 Ridgemont Dr, Abilene, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Abilene. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...

Ashmore Inn & Suites
2301 East I40, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...

Home2 Suites by Hilton Amarillo
8251 West Amarillo Blvd., Amarillo, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

Studio 6 Amarillo, TX – West Medical Center
6801 W Interstate 40, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...

Ashmore Inn and Suites
4019 S Loop 289, Lubbock, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Drury Inn & Suites Amarillo
8540 W Interstate 40, Amarillo, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

MCM Eleganté Hotel & Suites
801 Avenue Q, Lubbock, TX
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...

Country Inn & Suites by Radisson, Amarillo I-40 West, TX
2000 Soncy Road, Amarillo, TX
Fully refundable
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...

Embassy Suites Lubbock
5215 S Loop 289, Lubbock, TX
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the bar in our ...

Days Inn by Wyndham Amarillo East
1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Sleep Inn & Suites West Medical Center
6915 I-40 W, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Panhandle Plains

Studio 6 Amarillo, TX – West Medical Center
6801 W Interstate 40, Amarillo, TX
Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...
7.2/10 Good! (1,105 reviews)
"It was great!"
Reviewed on Mar 14, 2025

Home2 Suites by Hilton Amarillo
8251 West Amarillo Blvd., Amarillo, TX
Stay at this 3-star hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (999 reviews)
Great time.
"Very clean and comfortable."
Reviewed on Mar 16, 2025

Country Inn & Suites by Radisson, Amarillo I-40 West, TX
2000 Soncy Road, Amarillo, TX
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (2,036 reviews)
"Kids loved the pool"
Reviewed on Mar 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Panhandle Plains

La Quinta Inn & Suites by Wyndham Lubbock West Medical Centr
4115 Marsha Sharp Freeway, Lubbock, TX
Book a stay at this business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Fairfield Inn & Suites by Marriott Amarillo Central
I-40 East, 1911, Amarillo, TX
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Ashmore Inn & Suites
2301 East I40, Amarillo, TX
Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Panhandle Plains
- Hotels with a Pool in Panhandle Plains
- Pet-friendly Hotels in Panhandle Plains
- Hotels with an Indoor Pool in Panhandle Plains
- Hotels with Hot Tubs in Panhandle Plains
- Historic Hotels in Panhandle Plains
- Resorts & Hotels with Spas in Panhandle Plains
- Luxury Hotels in Panhandle Plains
- Winery Hotels in Panhandle Plains
- Apartment Hotel in Panhandle Plains
Top Points of Interests in Panhandle Plains
- Hotels near Texas Tech University
- Hotels near Sheppard Air Force Base
- Hotels near Possum Kingdom Lake
- Hotels near Palo Duro Canyon
- Hotels near Palo Duro Canyon State Park
- Hotels near Wichita Falls
- Hotels near Abilene Christian University
- Hotels near University Medical Center
- Hotels near Buddy Holly Center
- Hotels near Cadillac Ranch
- Hotels near Dyess Air Force Base
- Hotels near United Supermarkets Arena
- Hotels near Taylor County Expo Center
- Hotels near Possum Kingdom State Park
- Hotels near Abilene Zoo
- Hotels near Amarillo Civic Center
- Hotels near Midwestern State University
- Hotels near South Plains Mall
- Hotels near Hardin Simmons University
- Hotels near Wonderland Amusement Park
Cities near Panhandle Plains
- Abilene Hotels (135.87 mi)
- Hill Country Hotels (284.74 mi)
- Lawton Hotels (141.9 mi)
- Wichita Falls Hotels (135.35 mi)
- Weatherford Hotels (200.9 mi)
- Hobbs Hotels (167.65 mi)
- Gulf Coast Hotels (455.02 mi)
- Stephenville Hotels (203.98 mi)
- Canyon Hotels (82.33 mi)
- Big Spring Hotels (138.94 mi)
- Mineral Wells Hotels (183.46 mi)
- Clovis Hotels (136.01 mi)
- Decatur Hotels (197.91 mi)
- Brownwood Hotels (201.42 mi)
- Sweetwater Hotels (121.2 mi)
- Graford Hotels (172.17 mi)
- Dalhart Hotels (160.17 mi)
- Big Bend Hotels (249.41 mi)
- Graham Hotels (149.14 mi)
- Childress Hotels (39.46 mi)
Car Rentals Near Panhandle Plains
- Car rentals in Abilene
- Car rentals in Hill Country
- Car rentals in Lawton
- Car rentals in Wichita Falls
- Car rentals in Weatherford
- Car rentals in Hobbs
- Car rentals in Gulf Coast
- Car rentals in Stephenville
- Car rentals in Canyon
- Car rentals in Big Spring
- Car rentals in Mineral Wells
- Car rentals in Clovis
- Car rentals in Decatur
- Car rentals in Brownwood
- Car rentals in Sweetwater
- Car rentals in Graford
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Panhandle Plains
- The Big Texan Motel
- La Quinta Inn & Suites by Wyndham Lubbock Southwest
- Holiday Inn Express & Suites Amarillo West by IHG
- Overton Hotel and Conference Center
- La Quinta Inn & Suites by Wyndham Lubbock South
- Country Inn & Suites by Radisson, Lubbock Southwest, TX
- Country Inn & Suites by Radisson, Amarillo I-40 West, TX
- Ashmore Inn and Suites
- MCM Eleganté Hotel & Suites
- Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr
- Hyatt Place Lubbock
- MCM Elegante Suites Abilene