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Hotels in San Mateo

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Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (5,345 reviews)
Clean room, nice staff.

Reviewed on Mar 3, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,349 reviews)
It was central to the local attractions and the daily breakfast was excellent.

Reviewed on Mar 3, 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (2,890 reviews)
Rooms are perfect and staff is super friendly definitely recommend!

Reviewed on Mar 3, 2026

Handlery Union Square Hotel
Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown

3 out of 5
701 3rd St San Francisco CA
  • 42 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (2,020 reviews)
Everything is closed and is to easy to find transportation.

Reviewed on Mar 3, 2026

Hyatt Place San Francisco Downtown
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,455 reviews)
Windows are dirty: please have them cleaned more often

Reviewed on Mar 3, 2026

Hilton San Francisco Financial District
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
  • 43 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,011 reviews)
Manager was really nice made our stay possible

Reviewed on Mar 3, 2026

YOTEL San Francisco
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (2,102 reviews)
Breakfast buffet is $40 per person for what you get at some Holiday Inn’s for free

Reviewed on Mar 2, 2026

Hyatt Regency San Francisco
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4 out of 5
250 Beach Street San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this boutique hotel in San Francisco. Enjoy a 24-hour fitness center, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful ...
8.6/10 Excellent! (2,451 reviews)
This is a fun place in a top tourist spot, with parking. Works really well

Reviewed on Mar 2, 2026

Hotel Zephyr San Francisco
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy Burlingame CA
  • 14 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (4,842 reviews)
A nice stop when you have an early morning flight. Parking is easy, breakfast is good, and you can stroll along the bay.

Reviewed on Mar 2, 2026

Bay Landing San Francisco Airport Hotel
Hotel Julian

Hotel Julian

3 out of 5
940 Sutter Street San Francisco CA
  • 45 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Lombard Street and Pier 39 are located ...
8.6/10 Excellent! (643 reviews)
I wanna say Thank to everyone the entire staff and The Hotel. They made my stay beautiful. This is a Great Hotel

Reviewed on Mar 2, 2026

Hotel Julian
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (2,983 reviews)
Nice staff, clean room, great location.

Reviewed on Mar 2, 2026

Club Quarters Hotel in San Francisco
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

4 out of 5
1300 Columbus Avenue San Francisco CA
  • 48 min drive from San Mateo County Event Center
Book a stay at this family-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (3,845 reviews)
Clean, good security, lighting, & location.

Reviewed on Mar 2, 2026

Hotel Caza Fisherman's Wharf
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Mateo

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in San Mateo.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of San Mateo’s 5,323 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $125. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Mateo hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in San Mateo. No matter your reason for visiting San Mateo, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About San Mateo hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in San Mateo for as low as $125.

How many hotels are there in San Mateo?

With over 5,323 hotels in San Mateo, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $125.

How to find cheap car rentals in San Mateo?

Finding a cheap car rental deal in San Mateo is as easy as scoring cheap hotels in San Mateo. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.