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Hotels in San Mateo

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Choose from 4265 San Mateo Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (6,467 reviews)
"Good location in San Francisco. Public transportation was easily available. Great to have a parking garage onsite. We paid in advance."

Reviewed on Nov 6, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,739 reviews)
"Great location, excellent staff, good room, outstanding breakfast"

Reviewed on Nov 7, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
Hilton San Francisco Union Square
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2 out of 5
1075 Sutter St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and Netflix. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (2,032 reviews)
"For a comfortable stay that's affordable, this is a good choice. There's an excellent restaurant Eastern European, Dacha, for a little more elevated dining than the fried food places that were more common, and it's a few steps from the hotel front door. Delicious but more expensive than I would have ..."

Reviewed on Nov 6, 2026

FOUND Hotel Carlton, Nob Hill
The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay

3.5 out of 5
68 Monarch Bay Dr San Leandro CA
  • 31 min drive from San Mateo County Event Center
Book a stay at this golf hotel in San Leandro. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff ...
The Marina Inn on San Francisco Bay
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
8.8/10 Excellent! (1,730 reviews)
"Дуже хороший готель для відпочинку"

Reviewed on Nov 7, 2026

Parc 55 San Francisco - A Hilton Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff ...
Chancellor Hotel on Union Square
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (3,719 reviews)
"Central location. Had a family suite was a great price for that convenience"

Reviewed on Nov 6, 2026

Handlery Union Square Hotel
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Hyatt Regency San Francisco
The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
501 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the restaurant ...
9.2/10 Wonderful! (1,625 reviews)
"Beautiful hotel, staff were helpful and kind, and the room was clean/quaint."

Reviewed on Nov 7, 2026

The Marker Union Square San Francisco
Hotel Julian

Hotel Julian

3 out of 5
940 Sutter Street San Francisco CA
  • 45 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Lombard Street and Pier 39 are located ...
Hotel Julian
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Mateo

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in San Mateo.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of San Mateo’s 4,265 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $100. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Mateo hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in San Mateo. No matter your reason for visiting San Mateo, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About San Mateo hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in San Mateo for as low as $100.

How many hotels are there in San Mateo?

With over 4,265 hotels in San Mateo, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $100.

How to find cheap car rentals in San Mateo?

Finding a cheap car rental deal in San Mateo is as easy as scoring cheap hotels in San Mateo. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.