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Hotels in San Mateo

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Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,061 reviews)
The staff were super friendly. Great location and a nice price.

Reviewed on Apr 23, 2026

Club Quarters Hotel in San Francisco
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,402 reviews)
Breakfast was amazing and all staff were so polite and kind. The hotel was extremely clean and staff were always making sure things were in order. The only thing was our room was on the end of first floor and it was really, really loud from all of the street noise. Outside of that our stay was amazing! ...

Reviewed on Apr 24, 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this family-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (3,037 reviews)
Worth the money

Reviewed on Apr 25, 2026

Handlery Union Square Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,680 reviews)
Free internet, nice bar area, great morning coffee.

Reviewed on Apr 25, 2026

Hilton San Francisco Financial District
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,515 reviews)
This hotel is dated and not worth the price that they charge. Had to have them fix the toilet twice and have them fix the sink because it wasn’t draining. The sink shouldn’t have drainage issues at this price and management should check these things. Wallpaper peeling. I get that it’s a historic ...

Reviewed on Apr 23, 2026

Fairmont San Francisco
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
  • 43 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,007 reviews)
The breakfast was good, easy

Reviewed on Apr 25, 2026

YOTEL San Francisco
The Pickwick Hotel

The Pickwick Hotel

3.5 out of 5
85 5th St San Francisco CA
  • 43 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff ...
7.8/10 Good! (1,215 reviews)
Only thing I don’t like was housekeeping walking to go out room at 8 when check out wasn’t until noon . If I didn’t check out the room they shouldn’t be walking in at 8 am

Reviewed on Apr 25, 2026

The Pickwick Hotel
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy Burlingame CA
  • 14 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (4,851 reviews)
Give great food ideas

Reviewed on Apr 25, 2026

Bay Landing San Francisco Airport Hotel
Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

2 out of 5
326 S Airport Blvd South San Francisco CA
  • 24 min drive from San Mateo County Event Center
Book a stay at this business-friendly motel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the clean ...
6/10 (3,526 reviews)
The property you look like it was just recently renovated. The sink was kind of low and I’m a short person, but overall the sheets were clean in the room was clean.

Reviewed on Apr 24, 2026

Travelodge by Wyndham San Francisco Airport North
Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel

3 out of 5
380 S Airport Boulevard South San Francisco CA
  • 24 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,771 reviews)
I believe her name was Bianca from front desk, she was amazing! Made me feel comfortable and safe to be at this hotel since it was my first time. Free breakfast , even better! I will definitely stay here again!

Reviewed on Apr 25, 2026

Best Western Plus Grosvenor Airport Hotel
Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown

3 out of 5
701 3rd St San Francisco CA
  • 42 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (2,121 reviews)
This hotel stay was the best! We were in town visiting Oracle Park and Simon at the front desk was so kind and accommodating. The continental breakfast was delicious, the hotel was clean and it’s a quick walk to Oracle Park. 10/10 will return

Reviewed on Apr 25, 2026

Hyatt Place San Francisco Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Mateo

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Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of San Mateo’s 5,190 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $72. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Mateo hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in San Mateo. No matter your reason for visiting San Mateo, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About San Mateo hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in San Mateo?

With over 5,190 hotels in San Mateo, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $72.

How to find cheap car rentals in San Mateo?

Finding a cheap car rental deal in San Mateo is as easy as scoring cheap hotels in San Mateo. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.