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Hotels in San Mateo

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Choose from 4484 San Mateo Hotel Deals

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (2,303 reviews)
"A"

Reviewed on Jun 21, 2026

Hyatt Regency San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (5,884 reviews)
"My family and I had a good time staying there"

Reviewed on Jun 21, 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,503 reviews)
"Excellent location within walking distance of all major pier attractions. Fantastic breakfast and beautiful rooms. Stay here if traveling to SF, even with family."

Reviewed on Jun 20, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.6/10 Excellent! (1,357 reviews)
"The first tower that they placed us in smelled like absolute weed throughout the entire floor."

Reviewed on Jun 20, 2026

Hilton San Francisco Union Square
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (3,221 reviews)
"clean, excellant staff, a block from union square"

Reviewed on Jun 21, 2026

Handlery Union Square Hotel
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,248 reviews)
"Very nice and helpful staff! Impressed with how nice the lobby and the room looked. Confy bed, amazing shower! Many luxury touches, view from the room was great, location was perfect, supper close to the pier and the train station! They even let me check in 3 hours early at no charge!!! Will def ..."

Reviewed on Jun 21, 2026

Club Quarters Hotel in San Francisco
The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay

3.5 out of 5
68 Monarch Bay Dr San Leandro CA
  • 31 min drive from San Mateo County Event Center
Book a stay at this golf hotel in San Leandro. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,515 reviews)
"I only stayed one night but I had a nice view and easy parking. The room was clean and the bed was comfortable. The tv worked very well. The refrigerator was cold."

Reviewed on Jun 21, 2026

The Marina Inn on San Francisco Bay
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
8.8/10 Excellent! (1,489 reviews)
"Be ready to pay $80 for parking and extra fees in your card for no reason, entrance of hotel is full of homeless people not very safe!"

Reviewed on Jun 17, 2026

Parc 55 San Francisco - A Hilton Hotel
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,546 reviews)
"A historic hotel with a prime location in San Francisco. Our room was in well condition and its view was breathtaking!"

Reviewed on Jun 20, 2026

Fairmont San Francisco
Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd Burlingame CA
  • 12 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in Burlingame. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (2,810 reviews)
"Room was great. The separate little living room area and bedroom were very nice"

Reviewed on Jun 21, 2026

Crowne Plaza San Francisco Airport by IHG
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

4 out of 5
600 Airport Boulevard Burlingame CA
  • 10 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in Burlingame. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast ...
8.6/10 Excellent! (3,018 reviews)
"Everything was great. I would stay here again."

Reviewed on Jun 20, 2026

Hilton San Francisco Airport Bayfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Mateo

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in San Mateo.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of San Mateo’s 4,484 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $99. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Mateo hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in San Mateo. No matter your reason for visiting San Mateo, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About San Mateo hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in San Mateo for as low as $99.

How many hotels are there in San Mateo?

With over 4,484 hotels in San Mateo, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $99.

How to find cheap car rentals in San Mateo?

Finding a cheap car rental deal in San Mateo is as easy as scoring cheap hotels in San Mateo. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.