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Hotels in South San Francisco

Choose from 4951 South San Francisco Hotel Deals

Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel
3 out of 5
380 S Airport Boulevard, South San Francisco, CA
  • 6 min walk from South San Francisco Convention Center
The price is $130 per night from Jan 31 to Feb 1
$130
includes taxes & fees
Jan 31 - Feb 1
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the helpful ...
8.2/10 Very Good! (1,424 reviews)
"Close to airport and good breakfast options."

Reviewed on Jan 25, 2025

Best Western Plus Grosvenor Airport Hotel
La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
2.5 out of 5
20 Airport Blvd, South San Francisco, CA
  • 6 min walk from South San Francisco Convention Center
The price is $119 per night from Feb 7 to Feb 8
$119
includes taxes & fees
Feb 7 - Feb 8
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
8/10 Very Good! (2,054 reviews)
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Reviewed on Jan 25, 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport North
2 out of 5
326 S Airport Blvd, South San Francisco, CA
  • 4 min walk from South San Francisco Convention Center
The price is $63 per night from Jan 29 to Jan 30
$63
includes taxes & fees
Jan 29 - Jan 30
Book a stay at this business-friendly motel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the clean ...
5.8/10 (2,167 reviews)
One night stay
"The property is older and shows the wear and tear. But the bed was comfortable, check in was easy, we were able to park somewhat close to our room. It fit our needs as a location close to UCSF and easy to get to."

Reviewed on Jan 18, 2025

Travelodge by Wyndham San Francisco Airport North
DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd
4 out of 5
275 S Airport Blvd, South San Francisco, CA
  • 1 min walk from South San Francisco Convention Center
The price is $158 per night from Feb 2 to Feb 3
$158
includes taxes & fees
Feb 2 - Feb 3
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and a fitness center. Our guests praise the restaurant ...
8.4/10 Very Good! (1,622 reviews)
"Perfect for what I needed."

Reviewed on Jan 25, 2025

DoubleTree by Hilton San Francisco South Airport Blvd
Hotel Focus SFO
Hotel Focus SFO
3 out of 5
111 Mitchell Ave, South San Francisco, CA
  • 4 min walk from South San Francisco Convention Center
The price is $72 per night from Feb 23 to Feb 24
$72
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
7.4/10 Good! (1,358 reviews)
"When I hav a reservation ! The first thing I go do is pull down the sheets in the room. I found 2 hairs in the sheets! We called the lobby and they changed our room ASAP!"

Reviewed on Jan 25, 2025

Hotel Focus SFO
Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point Waterfront
3 out of 5
1300 Veterans Blvd, South San Francisco, CA
  • 29 min walk from South San Francisco Convention Center
The price is $132 per night from Feb 21 to Feb 22
$132
includes taxes & fees
Feb 21 - Feb 22
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the ...
8.2/10 Very Good! (1,203 reviews)
"Close hotel to SF airport with good cleanliness and access to highway. Lots or parking available and the area felt safe. The staff was also very friendly."

Reviewed on Jan 26, 2025

Sonesta Select San Francisco Airport Oyster Point Waterfront
Home2 Suites by Hilton San Francisco Airport North
Home2 Suites by Hilton San Francisco Airport North
3 out of 5
550 Gateway Blvd, South San Francisco, CA
  • 16 min walk from South San Francisco Convention Center
The price is $158 per night from Feb 23 to Feb 24
$158
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,005 reviews)
"Close transportation. Lobby staff very accommodating and friendly. Breakfast was the best I had while staying in SF."

Reviewed on Jan 25, 2025

Home2 Suites by Hilton San Francisco Airport North
Holiday Inn Golden Gateway, an IHG Hotel
Holiday Inn Golden Gateway, an IHG Hotel
3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
  • 24 min drive from South San Francisco Convention Center
The price is $152 per night from Feb 2 to Feb 3
$152
includes taxes & fees
Feb 2 - Feb 3
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
8.8/10 Excellent! (3,476 reviews)
"They helped me out with my car. I got in late after 2:00 a.m.. all the parking lots were closed and I had a roof rack carrier. They were very helpful."

Reviewed on Jan 24, 2025

Holiday Inn Golden Gateway, an IHG Hotel
Kimpton Alton Fisherman's Wharf, an IHG Hotel
Kimpton Alton Fisherman's Wharf, an IHG Hotel
4.5 out of 5
2700 JONES STREET, San Francisco, CA
  • 27 min drive from South San Francisco Convention Center
The price is $186 per night from Feb 6 to Feb 7
$186
includes taxes & fees
Feb 6 - Feb 7
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9/10 Wonderful! (1,304 reviews)
"Service, room, bed, amenties were excellent."

Reviewed on Jan 27, 2025

Kimpton Alton Fisherman's Wharf, an IHG Hotel
Club Quarters Hotel in San Francisco
Club Quarters Hotel in San Francisco
4 out of 5
424 Clay St, San Francisco, CA
  • 25 min drive from South San Francisco Convention Center
The price is $128 per night from Feb 20 to Feb 21
$128
includes taxes & fees
Feb 20 - Feb 21
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (2,146 reviews)
"Peaceful and clean"

Reviewed on Jan 26, 2025

Club Quarters Hotel in San Francisco
Hotel Caza Fisherman's Wharf
Hotel Caza Fisherman's Wharf
4 out of 5
1300 Columbus Avenue, San Francisco, CA
  • 27 min drive from South San Francisco Convention Center
The price is $203 per night from Feb 25 to Feb 26
$203
includes taxes & fees
Feb 25 - Feb 26
Stay at this 4-star family-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (3,488 reviews)
"I thought the hotel was better than I expected. Staff was great Room was spacious Great location"

Reviewed on Jan 21, 2025

Hotel Caza Fisherman's Wharf
Hilton San Francisco Financial District
Hilton San Francisco Financial District
4 out of 5
750 Kearny St, San Francisco, CA
  • 25 min drive from South San Francisco Convention Center
The price is $148 per night from Jan 31 to Feb 1
$148
includes taxes & fees
Jan 31 - Feb 1
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.4/10 Very Good! (905 reviews)
"Would recommend"

Reviewed on Jan 25, 2025

Hilton San Francisco Financial District
See all 4,951 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.