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Hotels in South San Francisco

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Check Last Minute South San Francisco Hotel Deals

Tonight Jan 27 - Jan 28This weekend Jan 27 - Jan 29

Last Minute Hot Rate® Hotel Deals in South San Francisco

We Hide Hotel Names So You Can Find 4-Star Hotels At 2-Star Prices. Choose the Location, Star Rating & Amenities. Let Hotwire Find You the Best Deal. Book Today!

Choose from 115 South San Francisco Hotel Deals

Rodeway Inn
Rodeway Inn
2 out of 5
222 S Airport Blvd, South San Francisco, CA, 94080
  • 2 min walk from South San Francisco Convention Center
The price is $60 per night from Jan 30 to Jan 31
$60
per night
Jan 30 - Jan 31
Stay at this business-friendly hotel in South San Francisco. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
3.5/5 Good! (1,015 reviews)
"It was great but I didn’t check the side of the beds"

Reviewed on Jan 15, 2023

Rodeway Inn
DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd
4 out of 5
275 S Airport Blvd, South San Francisco, CA, 94080
  • 2 min walk from South San Francisco Convention Center
The price is $139 per night from Feb 5 to Feb 6
$139
per night
Feb 5 - Feb 6
Stay at this 4-star business-friendly hotel in South San Francisco. Enjoy free WiFi, a fitness center, and onsite parking. Our guests praise the clean rooms ...
4.1/5 Very Good! (828 reviews)
"Staff was extremely friendly and helpful and facilities were clean."

Reviewed on Jan 24, 2023

DoubleTree by Hilton San Francisco South Airport Blvd
La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
2.5 out of 5
20 Airport Blvd, South San Francisco, CA, 94080
  • 6 min walk from South San Francisco Convention Center
The price is $87 per night from Feb 26 to Feb 27
$87
per night
Feb 26 - Feb 27
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
4/5 Very Good! (1,654 reviews)
"Good place to stay."

Reviewed on Jan 26, 2023

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Focus SFO
Hotel Focus SFO
3 out of 5
111 Mitchell Ave, South San Francisco, CA, 94080
  • 3 min walk from South San Francisco Convention Center
The price is $98 per night from Feb 16 to Feb 17
$98
per night
Feb 16 - Feb 17
Stay at this 3-star hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and the clean ...
3.7/5 Good! (1,052 reviews)
Not what was expected.
"The hotel has very limited hours for its airport shuttle service. It offers only a “to go” breakfast bag with no choices. Information on the Hotels.com website are very misleading."

Reviewed on Jan 24, 2023

Hotel Focus SFO
Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point Waterfront
3 out of 5
1300 Veterans Blvd, South San Francisco, CA, 94080
  • 29 min walk from South San Francisco Convention Center
The price is $107 per night from Feb 3 to Feb 4
$107
per night
Feb 3 - Feb 4
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free WiFi, breakfast, and a free airport shuttle. Our guests praise the helpful staff ...
4.2/5 Very Good! (1,031 reviews)
"The Hotel was clean modern and the staff was very friendly. Would stay again."

Reviewed on Jan 24, 2023

Sonesta Select San Francisco Airport Oyster Point Waterfront
Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel
3 out of 5
380 S Airport Boulevard, South San Francisco, CA, 94080
  • 6 min walk from South San Francisco Convention Center
The price is $96 per night from Feb 10 to Feb 11
$96
per night
Feb 10 - Feb 11
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free WiFi, an outdoor pool, and breakfast. Our guests praise the breakfast and the ...
4.1/5 Very Good! (1,136 reviews)
"Was a very nice hotel, clean and staff was great. Very close to car rental return and airport."

Reviewed on Jan 24, 2023

Best Western Plus Grosvenor Airport Hotel
Park Pointe Hotel
Park Pointe Hotel
2 out of 5
245 S Airport Blvd, South San Francisco, CA, 94080
  • 1 min walk from South San Francisco Convention Center
The price is $82 per night from Jan 28 to Jan 29
$82
per night
Jan 28 - Jan 29
Stay at this business-friendly hotel in South San Francisco. Enjoy free WiFi, free parking, and a conference center. Our guests praise the comfy rooms and the ...
2.9/5 (1,029 reviews)
"The price was good. Only one set of towels and the heater did not work"

Reviewed on Jan 22, 2023

Park Pointe Hotel
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
3 out of 5
1333 Veterans Boulevard, South San Francisco, CA, 94080
  • 27 min walk from South San Francisco Convention Center
The price is $154 per night from Jan 28 to Jan 29
$154
per night
Jan 28 - Jan 29
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free WiFi, breakfast, and a 24-hour fitness center. Our guests praise the helpful staff ...
4.5/5 Wonderful! (1,034 reviews)
10/10
"Check-in was fast and smooth. Room was quiet. (The hotel is next to tracks, but we didn't hear anything from our room.) AC unit was quiet and worked great. Gym was great, and they had headphones in case we forgot to pack ours. We really appreciated the tea in the lobby too! Breakfast is extra, and ..."

Reviewed on Jan 17, 2023

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
3 out of 5
1350 Veterans Boulevard, South San Francisco, CA, 94080
  • 4 min drive from South San Francisco Convention Center
The price is $139 per night from Jan 28 to Jan 29
$139
per night
Jan 28 - Jan 29
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful ...
4.2/5 Very Good! (704 reviews)
"The staff was extremely helpful and so kind! The room was spotless and the beds were comfy! My family of 5 only stayed for 1 night but we would definitely book with them again in the future. Plus the shuttle was perfectly on time and got us to the airport promptly!"

Reviewed on Jan 5, 2023

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Larkspur Landing South San Francisco - An All-Suite Hotel
Larkspur Landing South San Francisco - An All-Suite Hotel
3 out of 5
690 Gateway Blvd, South San Francisco, CA, 94080
  • 19 min walk from South San Francisco Convention Center
The price is $103 per night from Feb 3 to Feb 4
$103
per night
Feb 3 - Feb 4
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the clean rooms ...
3.9/5 Good! (1,012 reviews)
Rooms come with kitchen, but limited utensils.
"An OK hotel if the price is right, which would means it should the least costly of the hotels in this strip along Gateway Blvd. The kitchen is a great addition to the room, but poorly equipped as regards utensils (no pots, pans). Oddly, despite the room being equipped with a kitchen, including microwave, ..."

Reviewed on Jan 22, 2023

Larkspur Landing South San Francisco - An All-Suite Hotel
Holiday Inn Express San Francisco-Airport North, an IHG Hotel
Holiday Inn Express San Francisco-Airport North, an IHG Hotel
2.5 out of 5
373 S Airport Blvd, South San Francisco, CA, 94080
  • 6 min walk from South San Francisco Convention Center
The price is $115 per night from Jan 28 to Jan 29
$115
per night
Jan 28 - Jan 29
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
3.8/5 Good! (1,102 reviews)
"The lady at the front desk was wonderful. So was the gentleman on early morning the day I left. Super staff"

Reviewed on Jan 21, 2023

Holiday Inn Express San Francisco-Airport North, an IHG Hotel
Home2 Suites by Hilton San Francisco Airport North
Home2 Suites by Hilton San Francisco Airport North
3 out of 5
550 Gateway Blvd, South San Francisco, CA, 94080
  • 16 min walk from South San Francisco Convention Center
The price is $110 per night from Feb 19 to Feb 20
$110
per night
Feb 19 - Feb 20
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and ...
4.4/5 Wonderful! (482 reviews)
"Very close to airport, convenient, quiet, clean."

Reviewed on Jan 20, 2023

Home2 Suites by Hilton San Francisco Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in South San Francisco

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your South San Francisco hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in South San Francisco.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South San Francisco’s 115 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $60. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% South San Francisco hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South San Francisco. No matter your reason for visiting South San Francisco, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South San Francisco hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South San Francisco for as low as $60.

How many hotels are there in South San Francisco?

With over 115 hotels in South San Francisco, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $60.

How to find cheap car rentals in South San Francisco?

Finding a cheap car rental deal in South San Francisco is as easy as scoring cheap hotels in South San Francisco. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to South San Francisco now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to South San Francisco right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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