Hotels with Early Check-in in
South San Francisco

Photo by Catherine Edejer-McCormick

Check Last Minute South San Francisco Hotel Deals

Tonight Mar 29 - Mar 30This weekend Mar 29 - Mar 31

Featured South San Francisco Hotels with Early Check-in

Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport North
2 out of 5
326 S Airport Blvd, South San Francisco, CA
The price is $59 per night from Mar 31 to Apr 1
$59
per night
Mar 31 - Apr 1
Travelodge by Wyndham San Francisco Airport North
Larkspur Landing South San Francisco - An All-Suite Hotel
Larkspur Landing South San Francisco - An All-Suite Hotel
3 out of 5
690 Gateway Blvd, South San Francisco, CA
The price is $100 per night from Mar 31 to Apr 1
$100
per night
Mar 31 - Apr 1
Larkspur Landing South San Francisco - An All-Suite Hotel
Hampton Inn San Francisco Airport
Hampton Inn San Francisco Airport
2.5 out of 5
300 Gateway Blvd, South San Francisco, CA
The price is $101 per night from Apr 13 to Apr 14
$101
per night
Apr 13 - Apr 14
Hampton Inn San Francisco Airport
Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel
3 out of 5
380 S Airport Boulevard, South San Francisco, CA
The price is $95 per night from Mar 31 to Apr 1
$95
per night
Mar 31 - Apr 1
Best Western Plus Grosvenor Airport Hotel
DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd
4 out of 5
275 S Airport Blvd, South San Francisco, CA
The price is $105 per night from Apr 5 to Apr 6
$105
per night
Apr 5 - Apr 6
DoubleTree by Hilton San Francisco South Airport Blvd
Comfort Inn and Suites San Francisco Airport North
Comfort Inn and Suites San Francisco Airport North
2.5 out of 5
121 E Grand Ave, South San Francisco, CA
The price is $99 per night from Mar 31 to Apr 1
$99
per night
Mar 31 - Apr 1
Comfort Inn and Suites San Francisco Airport North
Four Points by Sheraton Hotel & Suites San Francisco Airport
Four Points by Sheraton Hotel & Suites San Francisco Airport
3 out of 5
264 South Airport Blvd., South San Francisco, CA
The price is $101 per night from Apr 5 to Apr 6
$101
per night
Apr 5 - Apr 6
Four Points by Sheraton Hotel & Suites San Francisco Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in South San Francisco

San Francisco is a city that has a lot going on, but you have your sights set on South San Francisco. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that South San Francisco has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of South San Francisco hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Francisco so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the South San Francisco underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the South San Francisco city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of South San Francisco cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in South San Francisco at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $59
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the South San Francisco hotel you want, book it, and never look back. Because your great escape is ahead of you.