Hotels with smoking rooms in
South San Francisco

Photo by Catherine Edejer-McCormick

Check Last Minute South San Francisco Hotel Deals

Tonight May 24 - May 25This weekend May 24 - May 26

Featured South San Francisco Hotels with smoking rooms

Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport North
2 out of 5
326 S Airport Blvd, South San Francisco, CA
The price is $59 per night from May 26 to May 27
$59
per night
May 26 - May 27
Travelodge by Wyndham San Francisco Airport North
Airport Inn
Airport Inn
2 out of 5
751 Airport Boulevard, South San Francisco, CA
The price is $110 per night from May 25 to May 26
$110
per night
May 25 - May 26
Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in South San Francisco

San Francisco is a city that has a lot going on, but you have your sights set on South San Francisco. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that South San Francisco has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of South San Francisco hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Francisco so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the South San Francisco underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the South San Francisco city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of South San Francisco cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in South San Francisco at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $59
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the South San Francisco hotel you want, book it, and never look back. Because your great escape is ahead of you.