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Independent in South San Francisco

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Featured South San Francisco Independent

Handlery Union Square Hotel
Handlery Union Square Hotel
3.5 out of 5
351 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Handlery Union Square Hotel
Oakland Airport Executive Hotel
Oakland Airport Executive Hotel
3 out of 5
150 Hegenberger Rd, Oakland, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Oakland. Enjoy free WiFi, room service, and parking (surcharge). Our guests praise the clean rooms and the overall ...
Oakland Airport Executive Hotel
Bay Landing San Francisco Airport Hotel
Bay Landing San Francisco Airport Hotel
3 out of 5
1550 Bayshore Hwy, Burlingame, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Bay Landing San Francisco Airport Hotel
The Pickwick Hotel
The Pickwick Hotel
3.5 out of 5
85 5th St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff ...
The Pickwick Hotel
Hotel Zephyr San Francisco
Hotel Zephyr San Francisco
4 out of 5
250 Beach Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff ...
Hotel Zephyr San Francisco
Beacon Grand, A Union Square Hotel
Beacon Grand, A Union Square Hotel
4 out of 5
450 Powell Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this historic hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
Beacon Grand, A Union Square Hotel
LUMA Hotel San Francisco
LUMA Hotel San Francisco
4 out of 5
100 Channel Street, San Francisco, CA
Stay at this 4-star hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful staff in our ...
LUMA Hotel San Francisco
Hotel Focus SFO
Hotel Focus SFO
3 out of 5
111 Mitchell Ave, South San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful ...
Hotel Focus SFO
The Marker Union Square San Francisco
The Marker Union Square San Francisco
4 out of 5
501 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
The Marker Union Square San Francisco
Chancellor Hotel on Union Square
Chancellor Hotel on Union Square
3.5 out of 5
433 Powell St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in ...
Chancellor Hotel on Union Square
The LINE San Francisco
The LINE San Francisco
4 out of 5
970 Market Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the bar and the helpful ...
The LINE San Francisco
The Marina Inn on San Francisco Bay
The Marina Inn on San Francisco Bay
2.5 out of 5
68 Monarch Bay Dr, San Leandro, CA
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in San Leandro. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff ...
The Marina Inn on San Francisco Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Independent hotels in South San Francisco

You’ve already taken the guesswork out of your next vacation. You know you want a Independent hotel in South San Francisco. What can you say? You like their style, they’re in a good part of South San Francisco, and they never let you down. New bar in town? You’re the first one to check it out. Spiciest item on the menu? You can take the heat. But even the best gamblers hedge their bets. No matter how crazy good your trip is, you want something familiar waiting for you at the end of the day.

All in a name

We all have favorites. There’s nothing wrong with knowing what you like. You like to stay at Independent near , South San Francisco to do the tourist thing (because sometimes it is fun) and then hit up the places that aren’t on the map. And no matter what fun you get into, you have Independent hotels with their comfy beds and thoughtful amenities waiting to tuck you in.

As you like it

Have a price you want to stick to, so you can paint the town red? Maybe, it’s all about the hotel features. Who couldn’t use a hot tub? Pick your pleasure by:

  • Hotwire Hot Rate: Grab the Independent hotel in South San Francisco at an absolute steal. After you book it, we’ll tell you the hotel name. You might nab that 4-star hotel for a 2-star price.
  • Price: How low can we go? Quite low in fact. Check out our prices per night, starting at $69.
  • Amenities: Grab a cocktail at the lounge and maybe wander upstairs to the rooftop terrace—all the stuff that makes a great vacay.

You’ve already done the hard part—figuring out where you want to stay. Now it’s time to use the money you saved to let the real fun begin. Underground shows? Off-beat attractions? Rooftop escapes? The choice is yours. The only thing wonderfully predictable about this trip is the Independent room you’ll be staying in.