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Uptown Vacation Packages

Uptown Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Baymont Inn and Suites by Wyndham Farmington, MO
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Tiny Houses of French Village
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Microtel Inn & Suites by Wyndham Sainte Genevieve
Comfort Inn Festus - St Louis South
Red Bud Country Inn
Hampton Inn Farmington

3-4 Night Vacations in Uptown

Price found within the past 48 hours. Click for updated prices.
Hilton Pennywell St. Louis at the Arch
The Wildwood Hotel
 The Royal Sonesta Chase Park Plaza St. Louis
Moonrise Hotel

5-7 Night Vacations in Uptown

Price found within the past 48 hours. Click for updated prices.
Microtel Inn & Suites by Wyndham Sainte Genevieve
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Tiny Houses of French Village
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Cheap Hotel Deals in Uptown

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
The Last Hotel

The Last Hotel

4.5 out of 5
1501 Washington Ave, St. Louis, MO
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Last Hotel
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Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Drury Plaza Hotel St. Louis at the Arch
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street, St. Louis, MO
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street, St. Louis, MO
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
St. Louis Union Station Hotel, Curio Collection by Hilton
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines

Find cheap hotels in Uptown

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Uptown hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Uptown.

Choosing the right hotel in Illinois has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Uptown’s 1,524 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $93. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Uptown hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Uptown. No matter your reason for visiting Uptown, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Uptown hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Uptown for as low as $93.

How many hotels are there in Uptown?

With over 1,524 hotels in Uptown, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $93.

How to find cheap car rentals in Uptown?

Finding a cheap car rental deal in Collinsville is as easy as scoring cheap hotels in Uptown. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Uptown now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Uptown right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.