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Uptown Vacation Packages

Uptown Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3 out of 5
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Stay at this hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Chesterfield Arts and Westfield Chesterfield Mall are located nearby.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Stay at this 3.5-star business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Six Flags St. Louis and Skid Row are located nearby.
Missouri Athletic Club

Missouri Athletic Club

3.5 out of 5
Downtown St. Louis
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the comfy rooms in our reviews. Popular attractions Gateway Arch and Busch Stadium are located nearby.
DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport

4 out of 5
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Stay at this 4-star business-friendly hotel in Maryland Heights. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Popular attractions Westport Plaza and Hollywood Casino Amphitheatre are located nearby.
The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Stay at this hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions St. Louis Zoo and St. Louis Union Station are located nearby.
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
The Hill
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Louis Zoo and St. Louis Union Station are located nearby.
Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Stay at this 3.5-star business-friendly hotel in Bridgeton. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular attractions Hollywood Casino Amphitheatre and Westport Plaza are located nearby.
Moonrise Hotel

Moonrise Hotel

4 out of 5
West End
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. Popular attractions St. Louis Zoo and St. Louis Union Station are located nearby.

3-4 Night Vacations in Uptown

Price found within the past 48 hours. Click for updated prices.
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
The Hill
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO

2.5 out of 5
per person
May 15 - May 19
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
The Cheshire

The Cheshire

4 out of 5
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
Moonrise Hotel

Moonrise Hotel

4 out of 5
West End
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)

Cheap Hotel Deals in Uptown

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd, St. Louis, MO
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Moonrise Hotel
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Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Drury Plaza Hotel St. Louis at the Arch
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd, St. Louis, MO
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
River City Casino & Hotel
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave, St. Louis, MO
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Le Méridien St. Louis Clayton
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street, St. Louis, MO
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street, St. Louis, MO
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Jul 15 - Sat, Jul 19
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$130 Roundtrip, just found
$130
Roundtrip
just found
Select Frontier Airlines flight, departing Tue, Jul 15 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Jul 19, priced at $130 just found
Frontier Airlines
Mon, Apr 28 - Wed, Apr 30
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$150 Roundtrip, found 9 hours ago
$150
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Mon, Apr 28 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Apr 30, priced at $150 found 9 hours ago
Delta
Wed, Apr 16 - Tue, Apr 22
LGA
LaGuardia
STL
Lambert-St. Louis Intl.
$178 Roundtrip, found 4 days ago
$178
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Apr 16 from LaGuardia to Lambert-St. Louis Intl., returning Tue, Apr 22, priced at $178 found 4 days ago
Spirit Airlines
Tue, Apr 8 - Tue, Apr 15
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$187 Roundtrip, found 6 days ago
$187
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Tue, Apr 8 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Apr 15, priced at $187 found 6 days ago