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Uptown Vacation Packages

3-4 Night Vacations in Uptown

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
May 23 - May 26
found 2 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
May 23 - May 26
found 2 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
The Cheshire

The Cheshire

4 out of 5
per person
May 23 - May 26
found 2 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)
Moonrise Hotel

Moonrise Hotel

4 out of 5
West End
per person
May 23 - May 26
found 2 hours ago
Roundtrip flight included
Charlotte (CLT) to St. Louis (STL)

Cheap Hotel Deals in Uptown

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd, St. Louis, MO
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Moonrise Hotel
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Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Drury Plaza Hotel St. Louis at the Arch
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd, St. Louis, MO
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
River City Casino & Hotel
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street, St. Louis, MO
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street, St. Louis, MO
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Pear Tree Inn St. Louis Near Union Station
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St, St. Louis, MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Jun 12 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$128 Roundtrip, found 3 days ago
$128
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Jun 14, priced at $128 found 3 days ago
Frontier Airlines
Sat, Apr 26 - Sat, May 3
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$129 Roundtrip, found 5 days ago
$129
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sat, Apr 26 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, May 3, priced at $129 found 5 days ago
Delta
Wed, Apr 16 - Tue, Apr 22
LGA
LaGuardia
STL
Lambert-St. Louis Intl.
$178 Roundtrip, found 1 day ago
$178
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Apr 16 from LaGuardia to Lambert-St. Louis Intl., returning Tue, Apr 22, priced at $178 found 1 day ago
Spirit Airlines
Tue, Apr 8 - Tue, Apr 15
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$187 Roundtrip, found 3 days ago
$187
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Apr 8 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Apr 15, priced at $187 found 3 days ago