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4 Star Hotels in South San Diego

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Featured 4 Star South San Diego Hotels

Manchester Grand Hyatt San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from Las Americas Premium Outlets
The price is $219 per night from Dec 18 to Dec 19
$219
includes taxes & fees
Dec 18 - Dec 19
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Manchester Grand Hyatt San Diego
Hilton San Diego Mission Valley
4 out of 5
Fully refundableReserve now, pay when you stay
  • 37 min drive from Las Americas Premium Outlets
The price is $141 per night from Dec 10 to Dec 11
$141
includes taxes & fees
Dec 10 - Dec 11
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
Hilton San Diego Mission Valley
Wyndham San Diego Bayside
4 out of 5
Fully refundableReserve now, pay when you stay
  • 30 min drive from Las Americas Premium Outlets
The price is $161 per night from Dec 1 to Dec 2
$161
includes taxes & fees
Dec 1 - Dec 2
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
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San Diego Marriott La Jolla
4 out of 5
  • 55 min drive from Las Americas Premium Outlets
The price is $162 per night from Dec 25 to Dec 26
$162
includes taxes & fees
Dec 25 - Dec 26
Stay at this 4-star business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
San Diego Marriott La Jolla
Hyatt Regency Mission Bay Spa and Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 38 min drive from Las Americas Premium Outlets
The price is $216 per night from Dec 15 to Dec 16
$216
includes taxes & fees
Dec 15 - Dec 16
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Hyatt Regency Mission Bay Spa and Marina
San Diego Marriott Gaslamp Quarter
4 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min drive from Las Americas Premium Outlets
The price is $162 per night from Dec 22 to Dec 23
$162
includes taxes & fees
Dec 22 - Dec 23
Book a stay at this business-friendly hotel in San Diego. Enjoy 2 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the bar and the helpful ...
San Diego Marriott Gaslamp Quarter
San Diego Mission Bay Resort
4 out of 5
Fully refundableReserve now, pay when you stay
  • 40 min drive from Las Americas Premium Outlets
The price is $242 per night from Dec 16 to Dec 17
$242
includes taxes & fees
Dec 16 - Dec 17
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
San Diego Mission Bay Resort
Loews Coronado Bay Resort
4 out of 5
Fully refundableReserve now, pay when you stay
  • 16 min drive from Las Americas Premium Outlets
The price is $244 per night from Dec 15 to Dec 16
$244
includes taxes & fees
Dec 15 - Dec 16
Stay at this 4-star beach hotel in Coronado. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Loews Coronado Bay Resort
Marriott Marquis San Diego Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from Las Americas Premium Outlets
The price is $217 per night from Dec 24 to Dec 25
$217
includes taxes & fees
Dec 24 - Dec 25
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in ...
Marriott Marquis San Diego Marina
Sheraton San Diego Hotel and Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 32 min drive from Las Americas Premium Outlets
The price is $156 per night from Dec 22 to Dec 23
$156
includes taxes & fees
Dec 22 - Dec 23
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 6 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
Sheraton San Diego Hotel and Marina
Lafayette Hotel & Club
4 out of 5
Fully refundableReserve now, pay when you stay
  • 36 min drive from Las Americas Premium Outlets
The price is $226 per night from Dec 1 to Dec 2
$226
includes taxes & fees
Dec 1 - Dec 2
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Lafayette Hotel & Club
Omni San Diego Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min drive from Las Americas Premium Outlets
The price is $223 per night from Dec 21 to Dec 22
$223
includes taxes & fees
Dec 21 - Dec 22
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Omni San Diego Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in South San Diego

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in South San Diego for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in South San Diego as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag South San Diego 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in South San Diego starting at $141 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded South San Diego 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.