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Hotels in South San Diego

Choose from 7400 South San Diego Hotel Deals

The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
  • 38 min drive from Las Americas Premium Outlets
The price is $168 per night from Feb 17 to Feb 18
$168
includes taxes & fees
Feb 17 - Feb 18
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 spa tubs. Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (3,136 reviews)
"Right on the water. Great staff."

Reviewed on Feb 8, 2025

The Dana on Mission Bay
Best Western Seven Seas
Best Western Seven Seas
3 out of 5
411 Hotel Circle South, San Diego, CA
  • 37 min drive from Las Americas Premium Outlets
The price is $105 per night from Feb 12 to Feb 13
$105
includes taxes & fees
Feb 12 - Feb 13
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 spa tubs. Our guests praise the pool and the restaurant in our ...
7.6/10 Good! (2,601 reviews)
"Great room, staff, and environment. Hot water didn’t work though"

Reviewed on Feb 7, 2025

Best Western Seven Seas
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and Marina
4 out of 5
1441 Quivira Rd, San Diego, CA
  • 38 min drive from Las Americas Premium Outlets
The price is $234 per night from Feb 13 to Feb 14
$234
includes taxes & fees
Feb 13 - Feb 14
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,462 reviews)
"It seems to be as if its a island getaway while at home."

Reviewed on Feb 7, 2025

Hyatt Regency Mission Bay Spa and Marina
Bay Club Hotel & Marina
Bay Club Hotel & Marina
3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
  • 31 min drive from Las Americas Premium Outlets
The price is $159 per night from Feb 24 to Feb 25
$159
includes taxes & fees
Feb 24 - Feb 25
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (2,438 reviews)
"Property is under construction so there is only 1 elevator working, no restaurant. Would have booked somewhere else if I knew up front. That being said there was no noise from the construction. The room was large & comfortable but needed more renovation"

Reviewed on Feb 6, 2025

Bay Club Hotel & Marina
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
  • 30 min drive from Las Americas Premium Outlets
The price is $178 per night from Feb 19 to Feb 20
$178
includes taxes & fees
Feb 19 - Feb 20
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,604 reviews)
"Handy to seaport, airport"

Reviewed on Feb 8, 2025

Wyndham San Diego Bayside
Omni San Diego Hotel
Omni San Diego Hotel
4 out of 5
675 L St, San Diego, CA
  • 28 min drive from Las Americas Premium Outlets
The price is $241 per night from Mar 6 to Mar 7
$241
includes taxes & fees
Mar 6 - Mar 7
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9/10 Wonderful! (1,829 reviews)
"Great staff me and my wife came here for a few days to have a quick getaway after our wedding and the Omni helped make it beautiful the room was amazing"

Reviewed on Feb 8, 2025

Omni San Diego Hotel
The Bristol Hotel San Diego
The Bristol Hotel San Diego
3.5 out of 5
1055 1st Ave, San Diego, CA
  • 30 min drive from Las Americas Premium Outlets
The price is $170 per night from Feb 17 to Feb 18
$170
includes taxes & fees
Feb 17 - Feb 18
Book a stay at this boutique hotel in San Diego. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,258 reviews)
"Great customer service, rooms, and area."

Reviewed on Feb 7, 2025

The Bristol Hotel San Diego
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
  • 36 min drive from Las Americas Premium Outlets
The price is $111 per night from Feb 13 to Feb 14
$111
includes taxes & fees
Feb 13 - Feb 14
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,551 reviews)
"Everything was excellent. Definitely booking again when in San Diego. Only thing Floor in room was dirty. Our white socks ended brown."

Reviewed on Feb 9, 2025

Comfort Inn Sea World Area
San Diego Marriott Gaslamp Quarter
San Diego Marriott Gaslamp Quarter
4 out of 5
660 K St, San Diego, CA
  • 28 min drive from Las Americas Premium Outlets
The price is $191 per night from Feb 21 to Feb 22
$191
includes taxes & fees
Feb 21 - Feb 22
Book a stay at this business-friendly hotel in San Diego. Enjoy 2 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the bar and the helpful ...
8.4/10 Very Good! (1,316 reviews)
"In San Diego for a convention the hotel was in the perfect location - surrounded by great restaurants, close walking distance to the convention center and close to the trolley."

Reviewed on Feb 10, 2025

San Diego Marriott Gaslamp Quarter
Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
  • 32 min drive from Las Americas Premium Outlets
The price is $231 per night from Mar 14 to Mar 15
$231
includes taxes & fees
Mar 14 - Mar 15
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 6 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,564 reviews)
"Nice"

Reviewed on Feb 10, 2025

Sheraton San Diego Resort
Paradise Point Resort & Spa
Paradise Point Resort & Spa
4 out of 5
1404 Vacation Rd, San Diego, CA
  • 40 min drive from Las Americas Premium Outlets
The price is $220 per night from Feb 23 to Feb 24
$220
includes taxes & fees
Feb 23 - Feb 24
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,063 reviews)
"Friendly staffs!! We had good time 😃"

Reviewed on Feb 3, 2025

Paradise Point Resort & Spa
San Diego Marriott La Jolla
San Diego Marriott La Jolla
4 out of 5
4240 La Jolla Village Dr, La Jolla, CA
  • 55 min drive from Las Americas Premium Outlets
The price is $171 per night from Feb 28 to Mar 1
$171
includes taxes & fees
Feb 28 - Mar 1
Stay at this 4-star business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.2/10 Very Good! (1,593 reviews)
"Very good staff and very good safe hotel"

Reviewed on Feb 10, 2025

San Diego Marriott La Jolla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South San Diego

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Frequently Asked Questions About South San Diego hotels

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How many hotels are there in South San Diego?

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Finding a cheap car rental deal in South San Diego is as easy as scoring cheap hotels in South San Diego. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.