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Hotels in South San Diego

Choose from 7585 South San Diego Hotel Deals

Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center

4 out of 5
1000 H Street, Chula Vista, CA
  • 15 min drive from Las Americas Premium Outlets
Stay at this 4-star spa hotel in Chula Vista. Enjoy 3 outdoor pools, a full-service spa, and 8 restaurants. Popular attractions Hotel del Coronado and San Diego ...
Gaylord Pacific Resort & Convention Center
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
  • 30 min drive from Las Americas Premium Outlets
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
  • 29 min drive from Las Americas Premium Outlets
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Manchester Grand Hyatt San Diego
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4 out of 5
830 Sixth Avenue, San Diego, CA
  • 29 min drive from Las Americas Premium Outlets
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in ...
Palihotel San Diego Gaslamp Quarter
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
  • 31 min drive from Las Americas Premium Outlets
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
The DEXTRO Little Italy, BW Premier Collection
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
  • 37 min drive from Las Americas Premium Outlets
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
Handlery Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
  • 38 min drive from Las Americas Premium Outlets
Stay at this 3.5-star hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular ...
The Dana on Mission Bay
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
  • 28 min drive from Las Americas Premium Outlets
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...
Hard Rock Hotel San Diego
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
  • 31 min drive from Las Americas Premium Outlets
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...
Bay Club Hotel & Marina
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd, San Diego, CA
  • 36 min drive from Las Americas Premium Outlets
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
Wyndham Garden San Diego Near SeaWorld
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 out of 5
800 Bay Marina Dr, National City, CA
  • 20 min drive from Las Americas Premium Outlets
Stay at this 3.5-star eco-certified hotel in National City. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in ...
Best Western Plus Marina Gateway Hotel
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy, San Diego, CA
  • 29 min drive from Las Americas Premium Outlets
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
Embassy Suites by Hilton San Diego Bay Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South San Diego

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your South San Diego hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in South San Diego.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South San Diego’s 7,585 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $108. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South San Diego hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South San Diego. No matter your reason for visiting South San Diego, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South San Diego hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South San Diego for as low as $108.

How many hotels are there in South San Diego?

With over 7,585 hotels in South San Diego, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $108.

How to find cheap car rentals in South San Diego?

Finding a cheap car rental deal in South San Diego is as easy as scoring cheap hotels in South San Diego. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.