Search for Cheap Deals on
Hotels in South San Diego

Check Last Minute South San Diego Hotel Deals

Tonight Jun 21 - Jun 22Next weekend Jun 27 - Jun 29

Choose from 7421 South San Diego Hotel Deals

Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
4 out of 5
333 W Harbor Dr, San Diego, CA
  • 29 min drive from Las Americas Premium Outlets
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,715 reviews)
"Enjoy the pool the pool bar was amazing staff very friendly"

Reviewed on Jun 20, 2025

Marriott Marquis San Diego Marina
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
4 out of 5
1 Market Pl, San Diego, CA
  • 29 min drive from Las Americas Premium Outlets
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,782 reviews)
"Very nice place to stay."

Reviewed on Jun 18, 2025

Manchester Grand Hyatt San Diego
Kings Inn San Diego
Kings Inn San Diego
2.5 out of 5
1333 Hotel Cir S, San Diego, CA
  • 37 min drive from Las Americas Premium Outlets
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.6/10 Excellent! (3,269 reviews)
"Everything was great except for the bedding. It was very stiff and rough, could definitely use some kind of softner. Think I’ll bring my own sheets next time. You can’t beat location, ease of access to everything in SanDiego. The pool is great."

Reviewed on Jun 21, 2025

Kings Inn San Diego
San Diego Marriott La Jolla
San Diego Marriott La Jolla
4 out of 5
4240 La Jolla Village Dr, La Jolla, CA
  • 55 min drive from Las Americas Premium Outlets
Stay at this 4-star business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
8.4/10 Very Good! (1,840 reviews)
"Great location, quiet neighborhood, walking distance to UCSD and Westfield UTC."

Reviewed on Jun 21, 2025

San Diego Marriott La Jolla
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
  • 38 min drive from Las Americas Premium Outlets
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,485 reviews)
"Everything was amazing"

Reviewed on Jun 17, 2025

The Dana on Mission Bay
Handlery Hotel
Handlery Hotel
3.5 out of 5
950 Hotel Cir N, San Diego, CA
  • 37 min drive from Las Americas Premium Outlets
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,805 reviews)
"Very clean hotel the front reception “Pamela” was so helpful and kind. I would definitely recommend my family and friends to stay here anytime"

Reviewed on Jun 20, 2025

Handlery Hotel
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
  • 36 min drive from Las Americas Premium Outlets
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,277 reviews)
"Very clean, inside and out."

Reviewed on Jun 19, 2025

Comfort Inn Sea World Area
DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission Valley
4 out of 5
7450 Hazard Center Dr, San Diego, CA
  • 38 min drive from Las Americas Premium Outlets
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.2/10 Very Good! (1,129 reviews)
"Excellent!"

Reviewed on Jun 18, 2025

DoubleTree by Hilton Hotel San Diego - Mission Valley
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
3 out of 5
3737 Sports Arena Blvd, San Diego, CA
  • 36 min drive from Las Americas Premium Outlets
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
7.2/10 Good! (3,889 reviews)
"Good place to stay lots of things nearby to do"

Reviewed on Jun 20, 2025

Wyndham Garden San Diego Near SeaWorld
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay Downtown
4 out of 5
601 Pacific Hwy, San Diego, CA
  • 29 min drive from Las Americas Premium Outlets
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,202 reviews)
"The property is very clean and staff are attentive."

Reviewed on Jun 15, 2025

Embassy Suites by Hilton San Diego Bay Downtown
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
  • 30 min drive from Las Americas Premium Outlets
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,708 reviews)
"The hotel is in good condition but outdated, the room was clean but again outdated. Great location, beautiful views of the bay and public transportation is just a block away. Parking is $50 day (totally worth it but no electric chargers). Hotel staff is very friendly. Overall 7/10."

Reviewed on Jun 20, 2025

Wyndham San Diego Bayside
Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
  • 32 min drive from Las Americas Premium Outlets
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8/10 Very Good! (2,726 reviews)
"Limited on site dinning"

Reviewed on Jun 18, 2025

Sheraton San Diego Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South San Diego

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your South San Diego hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in South San Diego.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South San Diego’s 7,421 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as . In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South San Diego hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South San Diego. No matter your reason for visiting South San Diego, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South San Diego hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South San Diego for as low as .

How many hotels are there in South San Diego?

With over 7,421 hotels in South San Diego, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as .

How to find cheap car rentals in South San Diego?

Finding a cheap car rental deal in South San Diego is as easy as scoring cheap hotels in South San Diego. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.